Peripheral Opioid Receptor Antagonists

DBCAT002566Pharmacologic classA06AH

Opioid receptor antagonists which act primarily on peripheral receptors due to limited ability to cross the blood brain barrier. Typically used to treat opioid-induced constipation. A DrugBank category of 5 drugs. 5 of them are approved.

ATC classification: A — ALIMENTARY TRACT AND METABOLISM
A06 — DRUGS FOR CONSTIPATION
A06A — DRUGS FOR CONSTIPATION
A06AH — Peripheral opioid receptor antagonists
Drugs: Alvimopan
Methylnaltrexone
Naldemedine
Naloxegol
Naloxone

What you can answer from here — as of June 22, 2018

5DrugsEach linked to its full drug card

Listed above

7Drug targetsEvery drug–target pair in the class, with bond type

1,486Marketed productsAcross the regions we cover, with dosage forms and routes

10Routes of administrationHow the drugs in this class are given

Which targets do Peripheral Opioid Receptor Antagonists share, and which companies have late-stage candidates in this class?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account