Prostacyclin Analogues

Accession Number

DBCAT002688 (DBCAT003426)

Description

Not Available

Drugs

Drug	Drug Description
Treprostinil	A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
Iloprost	A synthetic prostacyclin analog used to treat pulmonary arterial hypertension (PAH) and frostbites.
Epoprostenol	A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
Beraprost	For the treatment of pulmonary hypertension.

Drugs & Drug Targets

Drug	Target	Type
Treprostinil	P2Y purinoceptor 12	target
Treprostinil	Peroxisome proliferator-activated receptor delta	target
Treprostinil	Prostacyclin receptor	target
Treprostinil	Cytochrome P450 2C9	enzyme
Treprostinil	Prostaglandin E2 receptor EP2 subtype	target
Treprostinil	Prostaglandin D2 receptor	target
Treprostinil	Cytochrome P450 2C8	enzyme
Iloprost	Prostacyclin receptor	target
Iloprost	Tissue-type plasminogen activator	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Iloprost	Solute carrier organic anion transporter family member 2B1	transporter
Iloprost	Solute carrier organic anion transporter family member 2A1	transporter
Iloprost	Solute carrier organic anion transporter family member 3A1	transporter
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Iloprost	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Iloprost	Prostaglandin E2 receptor EP1 subtype	target
Iloprost	Prostaglandin D2 receptor 2	target
Iloprost	Serum albumin	carrier
Epoprostenol	P2Y purinoceptor 12	target
Epoprostenol	Prostacyclin receptor	target
Epoprostenol	Prostacyclin synthase	target
Beraprost	Prostacyclin receptor	target
Beraprost	Cytochrome P450 2C8	enzyme