Arylsulfatases
- Name
- Arylsulfatases
- Accession Number
- DBCAT002905
- Description
Enzymes that catalyze the hydrolysis of a phenol sulfate to yield a phenol and sulfate. Arylsulfatase A, B, and C have been separated. A deficiency of arylsulfatases is one of the causes of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.1.
- Drugs
Drug Drug Description Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. - Drugs & Drug Targets
Drug Target Type Galsulfase Perilipin-3 target Galsulfase Dermatan sulfate target