Lipopolysaccharides

Name
Lipopolysaccharides
Accession Number
DBCAT002924
Description

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Drugs
DrugDrug Description
EritoranInvestigated for use/treatment in sepsis and septicemia.
E5531Investigated for use/treatment in sepsis and septicemia.
Drugs & Drug Targets
DrugTargetType
EritoranToll-like receptor 4target
E5531Toll-like receptor 4target