Receptors, Peptide

Name
Receptors, Peptide
Accession Number
DBCAT002949
Description

Cell surface receptors that bind peptide messengers with high affinity and regulate intracellular signals which influence the behavior of cells.

Drugs
DrugDrug Description
Thrombomodulin AlfaInvestigated for use/treatment in blood preservative, blood (blood forming organ disorders, unspecified), sepsis and septicemia, and thrombosis.
AfliberceptA vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy.
DalanterceptDalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma).
VEGFR2-169VEGFR2-169 is under investigation in clinical trial NCT00655785 (Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)).
Drugs & Drug Targets
DrugTargetType
Thrombomodulin AlfaCoagulation factor Vtarget
Thrombomodulin AlfaProthrombintarget
AfliberceptVascular endothelial growth factor Atarget
AfliberceptPlacenta growth factortarget
AfliberceptVascular endothelial growth factor Btarget