Crown Compounds

Name
Crown Compounds
Accession Number
DBCAT003049
Description

Macrocyclic compounds analogous to CROWN ETHERS but which lack any OXYGEN atoms.

Drugs
DrugDrug Description
IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
Drugs & Drug Targets
DrugTargetType
IcotinibEpidermal growth factor receptortarget
IcotinibCytochrome P450 3A4enzyme
IcotinibCytochrome P450 1A2enzyme
IcotinibCytochrome P450 3A5enzyme