Transglutaminases

DBCAT003154Pharmacologic class

Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII... A DrugBank category of 1 drug. 1 of them is approved.

Also known as: Gamma-Glutamyltransferases, Glutaminyl-Peptide · gamma-Glutamyltransferases, Protein-Glutamine · Glutaminyl Peptide Gamma Glutamyltransferases · Glutaminyl-Peptide Gamma-Glutamyltransferases · Protein Glutamine gamma Glutamyltransferases
Drugs: Factor XIII (human)

What you can answer from here — as of June 26, 2017

1DrugEach linked to its full drug card

Listed above

2Drug targetsEvery drug–target pair in the class, with bond type

7Marketed productsAcross the regions we cover, with dosage forms and routes

2Routes of administrationHow the drugs in this class are given

Which targets do Transglutaminases share, and which companies have late-stage candidates in this class?

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