Thrombopoietin Receptor Agonist

All categories
Name
Thrombopoietin Receptor Agonist
Accession Number
DBCAT003455
Description

Not Available

Drugs
DrugDrug Description
RomiplostimA fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP).
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
AvatrombopagA thrombopoietin receptor agonist used pre-operatively to treat thrombocytopenia in patients with chronic liver disease and in patients with chronic refractory thrombocytopenia.
LusutrombopagA medication used to treat thrombocytopenia in patients with chronic liver disease scheduled to have a procedure.
Drugs & Drug Targets
DrugTargetType
RomiplostimThrombopoietin receptortarget
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
AvatrombopagCytochrome P450 2C8enzyme
AvatrombopagCytochrome P450 2C9enzyme
AvatrombopagThrombopoietin receptortarget
AvatrombopagP-glycoprotein 1transporter
AvatrombopagCytochrome P450 3A4enzyme
AvatrombopagATP-binding cassette sub-family G member 2transporter
AvatrombopagSolute carrier family 22 member 8transporter
LusutrombopagCytochrome P450 4A11enzyme
LusutrombopagP-glycoprotein 1transporter
LusutrombopagATP-binding cassette sub-family G member 2transporter
LusutrombopagThrombopoietin receptortarget