Interleukin-23 Antagonist

Name
Interleukin-23 Antagonist
Accession Number
DBCAT003460  (DBCAT004306)
Description

Not Available

Drugs
DrugDrug Description
UstekinumabA targeted antibody therapy used to manage inflammatory conditions such as plaque psoriasis, psoriatic arthritis, Crohn's Disease, and ulcerative colitis.
GuselkumabA monoclonal antibody used to treat moderate to severe plaque psoriasis.
TildrakizumabAn interleukin-23 antagonist used to treat moderate to severe plaque psoriasis.
RisankizumabAn interleukin-23 antagonist used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease in adults.
MirikizumabAn anti-IL-23 monoclonal antibody used as a second-line therapy for moderate-to-severe active ulcerative colitis.
Drugs & Drug Targets
DrugTargetType
UstekinumabInterleukin-12 subunit betatarget
UstekinumabInterleukin-23target
GuselkumabInterleukin-23 subunit alphatarget
TildrakizumabInterleukin-23target
TildrakizumabCytochrome P450 4A11enzyme
RisankizumabInterleukin-23target
MirikizumabInterleukin-23 subunit alphatarget