Miscellaneous Antidepressants

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Name: Miscellaneous Antidepressants
Accession Number: DBCAT003624
Description: Not Available
Drugs: Drug Drug Description
Bupropion A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Esketamine A NMDA receptor antagonist used for treatment-resistant depression.
Levomilnacipran A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults.
Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Tryptophan An amino acid commonly found as a component of total parenteral nutrition.
Drugs & Drug Targets: Drug Target Type
Bupropion Sodium-dependent noradrenaline transporter target
Bupropion Sodium-dependent serotonin transporter target
Bupropion 5-hydroxytryptamine receptor 3A target
Bupropion Solute carrier family 22 member 2 transporter
Bupropion Cytochrome P450 2E1 enzyme
Bupropion Cytochrome P450 2C9 enzyme
Bupropion Neuronal acetylcholine receptor subunit alpha-3 target
Bupropion Alpha-1-acid glycoprotein 1 carrier
Bupropion Cytochrome P450 2D6 enzyme
Bupropion Cytochrome P450 2B6 enzyme
Bupropion Sodium-dependent dopamine transporter target
Esketamine BDNF/NT-3 growth factors receptor target
Esketamine Neurotrophic factor BDNF precursor form target
Esketamine Elongation factor 2 target
Esketamine Glutamate receptor ionotropic, NMDA 2B target
Esketamine Cytochrome P450 2C9 enzyme
Esketamine Cytochrome P450 2C19 enzyme
Esketamine Cytochrome P450 3A4 enzyme
Esketamine Cytochrome P450 2B6 enzyme
Esketamine NMDA receptor target
Levomilnacipran ATP-dependent translocase ABCB1 transporter
Levomilnacipran Sodium-dependent noradrenaline transporter target
Levomilnacipran Sodium-dependent serotonin transporter target
Levomilnacipran Cytochrome P450 2J2 enzyme
Levomilnacipran Cytochrome P450 2D6 enzyme
Levomilnacipran Cytochrome P450 3A4 enzyme
Levomilnacipran Cytochrome P450 2C8 enzyme
Levomilnacipran Cytochrome P450 2C19 enzyme
Mirtazapine 5-hydroxytryptamine receptor 2A target
Mirtazapine 5HT3 serotonin receptor target
Mirtazapine Alpha-2A adrenergic receptor target
Mirtazapine 5-hydroxytryptamine receptor 2C target
Mirtazapine Kappa-type opioid receptor target
Mirtazapine Histamine H1 receptor target
Mirtazapine Cytochrome P450 1A2 enzyme
Mirtazapine Cytochrome P450 3A4 enzyme
Mirtazapine Cytochrome P450 2D6 enzyme
Mirtazapine Alpha-1 adrenergic receptors target
Mirtazapine Sodium-dependent serotonin transporter transporter
Mirtazapine Alpha-2 adrenergic receptors target
Tryptophan Tryptophan--tRNA ligase target
Tryptophan Tryptophan--tRNA ligase, mitochondrial target
Tryptophan Tryptophan 2,3-dioxygenase enzyme
Tryptophan Aromatic-L-amino-acid decarboxylase enzyme
Tryptophan Monocarboxylate transporter 8 transporter
Tryptophan Monocarboxylate transporter 10 transporter
Tryptophan Tryptophan--tRNA ligase enzyme
Tryptophan Tryptophan--tRNA ligase, mitochondrial enzyme
Tryptophan Tryptophan 5-hydroxylase 1 enzyme
Tryptophan Tryptophan--tRNA ligase, cytoplasmic enzyme
Tryptophan Tryptophan 5-hydroxylase 2 enzyme
Tryptophan Indoleamine 2,3-dioxygenase 1 target
Tryptophan Indoleamine 2,3-dioxygenase 1 enzyme
Tryptophan Tryptophan--tRNA ligase, cytoplasmic target

Drug	Drug Description
Bupropion	A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Esketamine	A NMDA receptor antagonist used for treatment-resistant depression.
Levomilnacipran	A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults.
Mirtazapine	A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Tryptophan	An amino acid commonly found as a component of total parenteral nutrition.

Miscellaneous Antidepressants

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