RNA Replicase Inhibitors

Name
RNA Replicase Inhibitors
Accession Number
DBCAT004208
Description
Not Available
Drugs
DrugDrug Description
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Drugs & Drug Targets
DrugTargetType
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
SofosbuvirP-glycoprotein 1transporter
SofosbuvirATP-binding cassette sub-family G member 2transporter
SofosbuvirRNA-dependent RNA-polymerasetarget
SofosbuvirLysosomal protective proteinenzyme
SofosbuvirCarboxylesteraseenzyme
SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
SofosbuvirUMP-CMP kinaseenzyme
SofosbuvirNucleoside diphosphate kinase Aenzyme