Tetrahydrofolates
- Name
- Tetrahydrofolates
- Accession Number
- DBCAT004542
- Description
Compounds based on 5,6,7,8-tetrahydrofolate.
- Drugs
Drug Drug Description Leucovorin A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Levoleucovorin A folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. - Drugs & Drug Targets
Drug Target Type Leucovorin Solute carrier family 22 member 8 transporter Levoleucovorin Serine hydroxymethyltransferase target