DBCAT004591Pharmacologic class

A structurally diverse group of endogenous molecules that includes the HMGB1 PROTEIN; S100 PROTEINS; HSP60, Hsp70, Cathelicidin, IL-33, and DEFENSINS. They are constitutively available, released upon tissue damage, and activate the immune system.

Which Alarmins are approved where, and how do their indications and safety profiles compare?

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