Proto-Oncogene Proteins c-sis

DBCAT004971Pharmacologic class

Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis. A DrugBank category of 1 drug. 1 of them is approved.

Drugs: Becaplermin

What you can answer from here — as of July 18, 2019

1DrugEach linked to its full drug card

Listed above

3Drug targetsEvery drug–target pair in the class, with bond type

7Marketed productsAcross the regions we cover, with dosage forms and routes

1Route of administrationHow the drugs in this class are given

Which targets do Proto-Oncogene Proteins c-sis share, and which companies have late-stage candidates in this class?

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