Serotonin-4 Receptor Agonist

Name
Serotonin-4 Receptor Agonist
Accession Number
DBCAT005474
Description

Not Available

Drugs
DrugDrug Description
PrucaloprideA 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
Drugs & Drug Targets
DrugTargetType
Prucalopride5-hydroxytryptamine receptor 4target
PrucaloprideCytochrome P450 3A4enzyme
PrucaloprideAlbumincarrier
PrucaloprideATP-dependent translocase ABCB1transporter
Tegaserod5-hydroxytryptamine receptor 4target
Tegaserod5-hydroxytryptamine receptor 2Btarget
Tegaserod5-hydroxytryptamine receptor 2Ctarget
Tegaserod5-hydroxytryptamine receptor 2Atarget
TegaserodSodium-dependent serotonin transportertransporter
TegaserodCytochrome P450 1A2enzyme
TegaserodCytochrome P450 2C8enzyme
TegaserodCytochrome P450 2D6enzyme
TegaserodCytochrome P450 2E1enzyme
TegaserodBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
TegaserodATP-dependent translocase ABCB1transporter