Small Interfering RNA
- Name
- Small Interfering RNA
- Accession Number
- DBCAT005484
- Description
Not Available
- Drugs
Drug Drug Description Patisiran A transthyretin-directed small interfering RNA used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. Givosiran A 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria. Lumasiran Lumasiran is an interfering RNA that silences hydroxyacid oxidase 1 for the treatment of primary hypoxaluria type 1. Vutrisiran A transthyretin-directed small interfering RNA used to treat polyneuropathy associated with hereditary transthyretin-mediated amyloidosis. - Drugs & Drug Targets
Drug Target Type Patisiran Transthyretin mRNA target Patisiran Serum albumin carrier Patisiran alpha1-acid glycoprotein carrier Givosiran ALAS1 mRNA target Lumasiran Hydroxyacid oxidase 1 target Lumasiran Serum albumin carrier Lumasiran Cytochrome P450 2C8 enzyme Vutrisiran Transthyretin mRNA target Vutrisiran Serum albumin carrier