Calicheamicins

DBCAT005567Pharmacologic class

Enediyne aminoglycosides derived from the bacterium MICROMONOSPORA ECHINOSPORA that are used as antineoplastic antibiotics. They bind to DNA in both healthy and tumor cells, resulting in strand scission and cell death. A DrugBank category of 2 drugs. 2 of them are approved.

Drugs: Gemtuzumab ozogamicin
Inotuzumab ozogamicin

What you can answer from here — as of January 13, 2022

2DrugsEach linked to its full drug card

Listed above

5Drug targetsEvery drug–target pair in the class, with bond type

12Marketed productsAcross the regions we cover, with dosage forms and routes

2Routes of administrationHow the drugs in this class are given

Which targets do Calicheamicins share, and which companies have late-stage candidates in this class?

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