Adrenal Cytotoxic Agents

Name
Adrenal Cytotoxic Agents
Accession Number
DBCAT005713
Description

Not Available

Drugs
DrugDrug Description
MitotaneAn adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing's syndrome.
Drugs & Drug Targets
DrugTargetType
MitotaneCytochrome P450 11B1, mitochondrialtarget
MitotaneAdrenodoxin, mitochondrialtarget
MitotaneSex hormone-binding globulincarrier
MitotaneCorticosteroid-binding globulincarrier
MitotaneCytochrome P450 3A4enzyme
MitotaneEstrogen receptor alphatarget
MitotaneProgesterone receptortarget
MitotaneAndrogen receptortarget
MitotaneThyroxine-binding globulincarrier
MitotaneP-glycoprotein 1transporter
MitotaneCytochrome P450 3A5enzyme
MitotaneCytochrome P450 3A7enzyme