Immune Checkpoint Proteins

DBCAT005820Pharmacologic class

Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules. A DrugBank category of 1 drug.

Drugs: Eftilagimod alfa

What you can answer from here — as of April 09, 2023

1DrugEach linked to its full drug card

Listed above

1Drug targetEvery drug–target pair in the class, with bond type

Which targets do Immune Checkpoint Proteins share, and which companies have late-stage candidates in this class?

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