Ribosome Inactivating Proteins, Type 2

DBCAT005853Pharmacologic class

Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lectin B subunit, linked by disulfide bridges. The lectin portion binds to cell surfaces and facilitates transport into the ENDOPLASMIC RETICULUM. A DrugBank category of 4 drugs.

Drugs: ONCOLYSIN B
XMMME-001-RTA
XomaZyme-791
Zolimomab aritox

What you can answer from here — as of July 22, 2023

4DrugsEach linked to its full drug card

Listed above

Which Ribosome Inactivating Proteins, Type 2 are approved where, and how do their indications and safety profiles compare?

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