Cystinuria (DBCOND0001382)

Identifiers

Synonyms

Cystinuria (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Penicillamine	A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis.	Solute carrier organic anion transporter family member 1B1transporter Coppertarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02780297	Prospective Research Rare Kidney Stones (ProRKS)	No drug interventions	Not Available	Not Available	recruiting
NCT04147871	Study Evaluating Patients With Cystinuria and Efficacy and Safety Exploratory Study in the Youngest Children	No drug interventions	treatment	2 / 3	not_yet_recruiting
NCT02026388	Rare Kidney Stone Consortium Biobank	No drug interventions	Not Available	Not Available	recruiting
NCT06065852	National Registry of Rare Kidney Diseases	No drug interventions	Not Available	Not Available	recruiting
NCT05058859	Long Term Clinical Efficacy of Sodium-glucose Cotransporter-2 (SGLT-2) Inhibitor in Cystinurics	Dapagliflozin	treatment	2	not_yet_recruiting
NCT02538016	TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study	Tolvaptan	treatment	Not Available	completed
NCT05048563	Registry of Thiola EC Therapy	No drug interventions	Not Available	Not Available	completed
NCT02910531	Lipoic Acid Supplement for Cystine Stone	No drug interventions	prevention	2	active_not_recruiting
NCT02125721	Effect of Increasing Doses of Cystine Binding Thiol Drugs on Cystine Capacity in Patients With Cystinuria	Penicillamine Tiopronin	treatment	4	completed
NCT02120105	Cystine Capacity Clinical Study (CysCap)	No drug interventions	Not Available	Not Available	completed
NCT04137978	Study Evaluating Patients With Cystinuria	Potassium bicarbonate Potassium citrate	treatment	2 / 3	withdrawn
NCT00169806	Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis	No drug interventions	prevention	Not Available	recruiting
NCT00381849	Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones	No drug interventions	treatment	1 / 2	completed
NCT04818034	The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study	Dapagliflozin	treatment	2	recruiting
NCT03539926	This Study Evaluates the Superiority of Daily Self-pH Monitorization of Lit-control®pH Meter Compared to the Monitorization of Reactive Strips (Standard of Care).	No drug interventions	other	Not Available	unknown_status
NCT02942420	Bucillamine Phase 2 Trial in Patients With Cystinuria	Bucillamine	treatment	2	unknown_status
NCT00588562	Rare Kidney Stone Consortium Patient Registry	No drug interventions	Not Available	Not Available	recruiting
NCT03836144	Effect of Urine Alkalinazation on Urinary Inflammatory Markers in Patients With Cystinuria	No drug interventions	Not Available	Not Available	completed
NCT02124395	Health-related Quality of Life in Rare Kidney Stone	No drug interventions	Not Available	Not Available	completed
NCT03663855	Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria	Tiopronin	treatment	2	completed