Tics (DBCOND0003654)

Identifiers

Synonyms

Tic / Tic (finding) / Habit tic (disorder) / Tic disorder (disorder) / Tic disorder, unspecified / Tic disorder / Tic Disorders

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Pimozide	An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder.	D(2) dopamine receptortarget Voltage-gated inwardly rectifying potassium channel KCNH2target Cytochrome P450 3A4enzyme Cytochrome P450 1A2enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter D(3) dopamine receptortarget Cytochrome P450 2D6enzyme Calmodulintarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05696769	Tourette Discrimination (TD) Stigma Scale	No drug interventions	Not Available	Not Available	recruiting
NCT03914664	Neural Correlates of Sensory Phenomena in Tourette Syndrome	No drug interventions	Not Available	Not Available	recruiting
NCT02605902	Trial to Demonstrate the Efficacy and Safety of Internet-delivered Behavioral Treatment for Adults With Tic Disorders	No drug interventions	treatment	Not Available	completed
NCT05547854	Evaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training Program	No drug interventions	health_services_research	Not Available	recruiting
NCT05047705	Investigating Distress Tolerance in Adults With Tourette Syndrome	No drug interventions	treatment	Not Available	completed
NCT06385535	Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder	No drug interventions	basic_science	Not Available	recruiting
NCT04578912	Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics	No drug interventions	treatment	Not Available	completed
NCT04498364	Extinction Learning in Adults With Tourette Syndrome	No drug interventions	treatment	Not Available	completed
NCT01043549	Repetitive Transcranial Magnetic Stimulation of the Posterior Parietal Cortex in Patients Suffering From Gilles de la Tourette Syndrome	No drug interventions	treatment	2	terminated
NCT01172288	N-acetylcysteine (NAC) for Children With Tourette Syndrome	Acetylcysteine	treatment	2	completed
NCT00169715	Database and Registry for Renal Diverticulum	No drug interventions	prevention	Not Available	completed
NCT03765463	Extinction Learning in Youth With Tourette Syndrome	No drug interventions	treatment	Not Available	completed