Irritability (DBCOND0012283)

Identifiers

Synonyms
Irritable behavior / Irritable Mood / Feeling irritable (finding) / Irritable / Feeling irritated / Irritable symptom

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Aripiprazole
An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
Passiflora incarnata flower
A herbal product indicated in the treatment of stress, nervousness, anxiety, irritability, and trouble sleeping.
No drug targets
Risperidone
A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05043805
Dextromethorphan Added on for Children With Chronic Irritabilitytreatment4enrolling_by_invitation
NCT06020261
Parent Management Training to Treat IrritabilityNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03863288
Dose Response Relationship of Oxytocin on Irritability in Youthsbasic_science1 / 2terminated
NCT03697837
Digital Parent Training for Disruptive Behaviors in ChildrenNo drug interventionstreatmentNot Availablecompleted
NCT04715932
Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)treatment2completed
NCT04635618
Psychotherapy Strategies for the Treatment of Professionals and Students From Essential Services With High Levels of Emotional Distress in the Context of COVID-19No drug interventionstreatmentNot Availableunknown_status
NCT05974241
Irritability in Children With ADHD and Emotion Dysregulationtreatment4completed
NCT05930886
Focus Groups in Ethnically and Racially Diverse FamiliesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05528926
RESist Against Irritability Superiority TrialNo drug interventionsotherNot Availablerecruiting
NCT06133231
Optimizing Research With Diverse FamiliesNo drug interventionsotherNot Availablenot_yet_recruiting
NCT01675960
Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Childrentreatment2terminated
NCT03592368
Hostile Interpretation Bias Training to Treat IrritabilityNo drug interventionsbasic_scienceNot Availablecompleted
NCT00627250
Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic IrritabilitytreatmentNot Availablecompleted
NCT02507284
Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Diseasetreatment2completed
NCT05260398
Examining the Impacts on In-School Behaviors of In-Home Videogame PlayNo drug interventionstreatmentNot Availableunknown_status
NCT05388656
Estrogen Variability and Irritability During the Menopause Transitionbasic_science4recruiting
NCT01326663
Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.No drug interventionstreatmentNot Availableunknown_status
NCT06505980
Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent TrainingNo drug interventionstreatment2not_yet_recruiting
NCT04776304
Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress SymptomsNo drug interventionstreatmentNot Availablecompleted
NCT05414708
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress SymptomsNo drug interventionstreatmentNot Availablerecruiting
NCT02552147
Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autismtreatment1completed
NCT00866411
Cranial Electrotherapy Stimulation (CES) for Soldiers With Combat-Related SymptomsNo drug interventionstreatmentNot Availableunknown_status
NCT02531893
Psychological Treatments for Youth With Severe Irritability.No drug interventionsNot AvailableNot Availablerecruiting
NCT06484088
Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy VolunteersNo drug interventionsbasic_science0not_yet_recruiting
NCT03238118
Attention Bias Modification, Attention Control and Psychoeducation for Irritability in Children and AdolescentsNo drug interventionstreatmentNot Availablecompleted
NCT03854019
Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Diseasetreatment3completed
NCT01508741
Use Of The Dietary Supplement 5-ALA And Its Relationship With Sleep And MoodNo drug interventionsNot AvailableNot Availablecompleted
NCT04632082
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19No drug interventionspreventionNot Availableunknown_status
NCT03464773
Pain and Irritability in Non-Verbal ChildrenNo drug interventionshealth_services_researchNot Availablecompleted
NCT01283568
Safety and Efficacy Study of Gamaline+Hipericin in PMSNo drug interventionsNot AvailableNot Availableunknown_status
NCT01502969
Safety and Immunogenicity Assessment of Rotavin-M1 in Vietnamese Childrenprevention2 / 3completed
NCT01965184
Cognitive-Behavioral Therapy for Disruptive Behavior in Children and AdolescentsNo drug interventionstreatmentNot Availablecompleted
NCT01377571
A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy InfantsNot Available2completed
NCT01375907
Safety Study of a Rotavirus Vaccine (Rotavin-M1) Among Healthy AdultsNo drug interventionsNot Available1completed
NCT01942785
Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Therapytreatment3completed
NCT02054949
Treatment Resistant Epilepsy and N-Acetyl CysteinetreatmentNot Availablewithdrawn
NCT04654260
Behavior Therapy for Irritability in AutismNo drug interventionstreatmentNot Availablerecruiting
NCT04619862
Efficacy of Gabapentin in Treating Pain in Children With SNI (Gabapentin Trial)treatment2recruiting