NCT05326997
Treatment of Melasma With Yellow Light Compared to Tranexamic Acid No drug interventions treatment Not Available terminated NCT06644157
Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser No drug interventions treatment Not Available not_yet_recruiting NCT06616311
Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color. No drug interventions treatment Not Available not_yet_recruiting NCT04308421
Efficacy of Red Light in the Treatment of Pigmentary Disorders No drug interventions treatment Not Available unknown_status NCT03585179
Oral and Topical Tranexamic Acid for the Treatment of Melasma treatment 3 unknown_status NCT03686787
Oral Tranexamic Acid and Laser for Treatment of Melasma treatment 4 unknown_status NCT05656833
Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma No drug interventions treatment Not Available recruiting NCT03899233
Tranexamic Acid vs. Combination With Fractional Carbon Dioxide Laser in Melasma treatment 4 unknown_status NCT05790577
Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma treatment 2 completed NCT03826277
Efficacy of Melanostop Peeling for Improvement of Melasma No drug interventions supportive_care Not Available active_not_recruiting NCT06454747
Randomized Study Using SM-030 Gel for Adults With Melasma No drug interventions treatment 2 recruiting NCT03877445
Study of the Influence of Blue Light Emitted by Computer / Television Screens on Melasma MELABLUE Study No drug interventions other Not Available completed NCT06174545
Effectiveness and Safety of Pigment Solution Program (PSP) as Adjuvant Therapy in Melasma No drug interventions other Not Available recruiting NCT05911698
Fractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma. No drug interventions treatment Not Available not_yet_recruiting NCT02892071
Tri-split Face Study of Skin Resurfacing Modalities for the Treatment of Melasma No drug interventions treatment 1 withdrawn NCT06313307
The Efficacy in Treatment of Facial Melasma Combined With Thulium 1927-nm Fractional Laser and Topical H2R Antagonist No drug interventions treatment Not Available completed NCT02977507
Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma treatment Not Available completed NCT03953209
Spironolactone for the Treatment of Melasma treatment 1 withdrawn NCT03415685
Lutronic PicoPlus Exploratory Clinical Trial No drug interventions treatment Not Available terminated NCT00717652
Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma treatment 2 / 3 suspended NCT05362500
Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma treatment 1 completed NCT03308370
Platelet Rich Plasma in Treatment of Melasma treatment 3 unknown_status NCT03982849
Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma treatment 2 completed NCT06516419
Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy other Not Available recruiting NCT03565341
Efficacy and Safety of PiQo4 Device for Treatment of Melasma No drug interventions treatment Not Available completed NCT02110134
A Study of the RevLite Laser System for the Treatment of Refractory Mixed Type Melasma No drug interventions device_feasibility Not Available completed NCT06201624
Oral Isotretinoin in Melasma a Randomized Controlled Trial treatment 1 recruiting NCT06516224
Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma No drug interventions treatment Not Available not_yet_recruiting NCT03472235
Microneedle and Trichloroaceticacid in Treatment of Melasma No drug interventions treatment Not Available unknown_status NCT03751163
Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma treatment 3 completed NCT01850186
Comparative Study of Dual Yellow Laser Versus Stabilized Kilnman Preparation in the Treatment of Melasma No drug interventions treatment Not Available completed NCT02061839
Prevention of Melasma Relapse During Summertime No drug interventions prevention Not Available completed NCT02138539
Evaluation of an Herbal-Based De-Pigmenting System treatment 4 completed NCT04765930
Combined Q-switched Nd:YAG Laser and Platelet Rich Plasma Versus Q- Switched Nd:YAG Laser Alone in Melasma No drug interventions treatment Not Available unknown_status NCT04417348
Opsin Receptors in Melasma basic_science Not Available completed NCT05942248
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis No drug interventions other Not Available recruiting NCT03456674
LaseMD System for the Treatment of Melasma No drug interventions treatment Not Available active_not_recruiting NCT00500162
Comparison of Two Tri-Luma® Maintenance Regimens in the Treatment of Melasma No drug interventions treatment 4 completed NCT03923062
Different Dermatological Approaches the Treatment of Melasma treatment 4 unknown_status NCT01136629
Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion No drug interventions Not Available Not Available unknown_status NCT03040089
Efficacy and Safety of Picosecond, Neodymium-doped Yttrium Aluminum Garnet Laser Therapy Using 1,064 nm and 595 nm No drug interventions treatment Not Available completed NCT05031689
Green Banana Peel Extract for Melasma Treatment treatment 1 completed NCT06013540
Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma. treatment 2 active_not_recruiting NCT04346901
Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma other 1 completed NCT05099601
Silymarin Cream Versus Combined Silymarin Cream and Microneedling in Treatment of Melasma treatment 4 unknown_status NCT05013801
A Clinical Study to Evaluate the Effect of Facial Serum Q69 in Moderating the Appearance of Mild to Moderate Melasma treatment Not Available completed NCT05236569
Effectiveness and Safety of Intradermal Tranexamic Acid Injection as An Adjunctive Treatment for Melasma in Skin Type IV - V treatment Not Available completed NCT06010810
The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma treatment 3 active_not_recruiting NCT01245881
Fractional Photothermolysis for Treating Melasma No drug interventions treatment Not Available completed NCT05626881
Efficacy of Intralesional PRP +/- Topical Silymarin in the Treatment of Melasma treatment Not Available recruiting NCT03008655
1064-nm Q-switched Nd:YAG Laser and Intradermal Tranexamic Acid for Melasma No drug interventions treatment Not Available unknown_status NCT01162850
Oral Polypodium Leucotomos for Melasma No drug interventions treatment Not Available completed NCT03392623
DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. other 0 completed NCT03674203
Efficacy of Platelet-rich Plasma in Treatment of Melasma treatment 2 completed NCT04597203
Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial treatment Not Available unknown_status NCT01092884
Polypodium Leucotomos Extract for the Treatment of Melasma No drug interventions treatment Not Available completed NCT01952379
Inflammation in Melasma: Study of Its Infiltrate and the Expression of Acute and Chronic Mediators No drug interventions Not Available Not Available completed NCT05969587
Cysteamine Compared to Hydroquinone in Melasma treatment 3 completed NCT06221787
Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration No drug interventions treatment Not Available recruiting NCT00467233
Study of Acid Peel and Laser for the Treatment of Melasma No drug interventions treatment Not Available completed NCT03878433
Oral Superoxide Dismutase (GLISODin) to Decrease Melasma Severity. other Not Available completed NCT05884151
Comparison of Intralesional Tranexamic Acid and Platelets Rich Plasma in the Treatment of Melasma treatment 1 completed NCT00509977
Study of Light Treatment and Laser Treatment for Melasma No drug interventions treatment Not Available completed NCT04599205
Evaluation of Laser and Tranexamic Acid in Treatment of Melasma treatment 2 / 3 unknown_status NCT00469183
Assessment of Atrophogenic Potential of Triple Combination Cream for Treatment of Melasma treatment 4 completed NCT00669071
Treatment w/ Tri-Luma® Cream & Intense Pulsed Light (IPL) vs a Mild Inactive Control Cream & Intense Pulsed Light (IPL) in Melasma treatment 4 terminated NCT02095756
Combination Alexandrite Laser and Topical Therapy vs Topical Therapy Alone for Treatment of Melasma No drug interventions treatment Not Available completed NCT01695356
Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma treatment 4 completed NCT01661556
Clinical Trial of Hydroquinone Versus Miconazol in Melasma treatment 4 unknown_status NCT03153852
Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid treatment 4 unknown_status NCT03049059
A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma treatment 2 completed NCT05698342
Tissue-resident Memory T Cells Expression in Melasma No drug interventions Not Available Not Available completed NCT03848013
Treatment of Melasma Using Q-switched Nd: YAG Laser and Fractional CO2 Laser Separately and in Combination No drug interventions treatment Not Available completed NCT05887219
Comparison of Azelaic Acid 20 % Cream Versus Hydroquinone 4% Cream as an Adjuvant to Oral Tranexamic Acid in Melasma treatment 1 completed NCT04359719
Comparison Between Free Thyroxine and Thyroid Stimulating Hormone Levels on Melasma Severity No drug interventions Not Available Not Available completed NCT02730819
Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma No drug interventions treatment 2 completed NCT04602819
Photoaging Reversing After Picosecond Laser With DLA Assessed by Cellular Resolution OCT in Asian Patient With Melasma No drug interventions treatment Not Available completed NCT02812719
Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid Peel treatment 0 withdrawn NCT06153134
Curcuma Xanthorriza Roxb. 10% Cream for Melasma treatment 0 recruiting NCT03475524
USE THE SYSTEMIC METFORMIN IN MELASMA treatment 4 unknown_status NCT01745224
Revlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type Melasma No drug interventions device_feasibility Not Available terminated NCT01001624
Melanil in the Treatment of Melasma No drug interventions treatment 3 completed NCT00848458
Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma No drug interventions treatment 2 / 3 unknown_status NCT06415435
Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma No drug interventions treatment Not Available recruiting NCT04137263
Study Evaluating the Efficacy of DOSE Formulations in Treating Melasma and Cutaneous Signs of Aging No drug interventions treatment Not Available completed NCT00616239
Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women treatment 4 completed NCT06278948
Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma treatment Not Available recruiting NCT00472966
Efficacy and Safety of Therapy With Tri-Luma® Cream in Sequence With Glycolic Acid Peels for Melasma treatment 4 completed NCT03963466
A Clinical Observation of 1064-nm Q-Switched Fractional Laser Combined With Oral Tranexamic Acid on Treating of Melasma. treatment Not Available completed NCT04823520
Trichloroacetic Acid (TCA) Combined With Microdermabrasion in Treatment of Melasma No drug interventions treatment 4 unknown_status NCT02385994
A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin No drug interventions treatment Not Available completed NCT00166192
Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid No drug interventions treatment 4 completed NCT05909072
Tranexamic Acid With Microneedling in Melasma treatment 2 not_yet_recruiting NCT00771355
In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy No drug interventions Not Available Not Available terminated NCT03618277
Identification of Biomarkers and Characterization of Melasma No drug interventions basic_science Not Available withdrawn NCT06418568
Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma No drug interventions treatment Not Available recruiting