acute chemotherapy-induced nausea and vomiting (DBCOND0025637)
Identifiers
- Synonyms
- Acute chemotherapy induced nausea and vomiting / Acute caused and vomiting caused by Chemotherapy / Acute Chemotherapy-Induced Nausea and Vomiting / Acute naused and vomiting caused by Chemotherapy
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Netupitant An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy.- Substance-P receptortarget
- Cytochrome P450 3A43enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2D6enzyme
- Cytochrome P450 3A4enzyme
- ATP-dependent translocase ABCB1transporter
Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.- 5-hydroxytryptamine receptor 3Atarget
- Cytochrome P450 2D6enzyme
- Cytochrome P450 3A4enzyme
- Cytochrome P450 1A2enzyme
- Clinical Trials
- Not Available