varicosities of the great saphenous vein (DBCOND0025660)

Identifiers

Synonyms
Vein, Varicose / Veins, Varicose / Varicose Veins / Varicose Vein / Asymptomatic varicose veins of unspecified lower extremity / Vein varicose / Varicose veins NOS / Venous varices / Varicosity / Venous ectasia (morphologic abnormality) / Venous varices (disorder) / Varix (morphologic abnormality)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Escin
An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
No drug targets
Heparin
An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
Polidocanol
A sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
No drug targets
Troxerutin
Troxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03304834
Treatment of Insufficient Superficial and Perforating Veins of the Lower Limb Using HIFUNo drug interventionstreatmentNot Availablecompleted
NCT04908527
Effect of Walking to the Operating Room on Preoperative AnxietyNo drug interventionspreventionNot Availablecompleted
NCT02988063
Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUstreatment4withdrawn
NCT00442364
Safety Study of Varisolve® Procedure for Treatment of Varicose Veins in Patients With Right-to-left Cardiac Shunttreatment2completed
NCT04006184
Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal AblationNo drug interventionsNot AvailableNot Availablecompleted
NCT04280679
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFUNo drug interventionstreatmentNot Availablecompleted
NCT05342779
Radio Frequency Ablation Versus Stripping of Great Saphenous Vein in Management of Primary Varicose Veins , Comparative StudyNo drug interventionstreatmentNot Availableunknown_status
NCT05247333
Implementation of a Minor Ailment Service in Community Pharmacy PracticeNo drug interventionshealth_services_researchNot Availablecompleted
NCT03810677
Treatment of Varicose Veins With the ELVeS® Radial® 2ring Slim Fiber. Are There Limitations?No drug interventionsNot AvailableNot Availablecompleted
NCT02522845
Compression Therapy Following Endothermal AblationNo drug interventionstreatmentNot Availablecompleted
NCT00991497
A Trial to Compare the Outcome of Localised Varicosity Compression for 24 Hours and 5 Days After Foam Sclerotherapy to Truncal VaricesNo drug interventionstreatmentNot Availablecompleted
NCT04524793
Efficacy and Safety of Endovenous Microwave Ablations for Treatment of Varicose Veins in SingaporeNo drug interventionstreatmentNot Availableunknown_status
NCT03653793
LivRelief Varicose Veins Cream in the Treatment of Varicose VeinsNo drug interventionstreatmentNot Availablecompleted
NCT02936271
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient SettingNo drug interventionstreatmentNot Availablewithdrawn
NCT04339088
High Intensity Focused Ultrasound in PAtients With Varicose Veins in SingaporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT02114307
REVITIVE for the Treatment of Patients With Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT04384315
Efficacy and Safety of Endovenous Radio Frequency (EVRF) for Treatment of Varicose Veins in SingaporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT02454452
Comparison of Radiofrequency, Vein Stripping and CHIVA for Venous InsufficencyNo drug interventionstreatmentNot Availablecompleted
NCT03283800
Copper Impact on Venous Insufficiency and LipodermatosclerosisNo drug interventionssupportive_careNot Availablecompleted
NCT05663359
Study on Treatment of Varicose Veins by Endovenous Laser (1940 nm vs 1470 nm)No drug interventionstreatmentNot Availablerecruiting
NCT04339075
Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingAporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT05312970
Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)other4terminated
NCT02584842
Rivaroxaban in Endovenous Laser Ablation With and Without MiniphlebectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT01200199
Validity of Electronic Diary for Monitoring Varicose Veins SymptomsNo drug interventionsNot AvailableNot Availablecompleted
NCT02017106
Concomitant or Sequential Phlebectomy After Endovenous Laser Therapy for Varicose VeinsNo drug interventionstreatmentNot Availablecompleted
NCT04436549
Pathology, Venous Disease, and Clinical CorrelationsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02080013
Endovenous Radiofrequency Versus Laser Ablation for the Treatment of Great Saphenous Vein RefluxNo drug interventionstreatmentNot Availablecompleted
NCT01942941
Peripheral Vascular Disease and Nerve StimulationNo drug interventionstreatmentNot Availablecompleted
NCT00759434
A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic ValueNo drug interventionstreatmentNot Availablecompleted
NCT01508624
Evaluation of Interventions to Improve Pain Relief, Perceived Anxiety and Recovery in Participants Receiving Office Based SurgeryNo drug interventionssupportive_careNot Availablecompleted
NCT05655416
Treatment of Great Saphenous Vein VaricositiesNo drug interventionstreatmentNot Availablecompleted
NCT03850496
DESIVI: Dosing of Electrical Stimulation in Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT05398458
Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case ReportNo drug interventionsNot AvailableNot Availablecompleted
NCT03744858
The Role of Pyroptosis in Chronic Venous DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01426035
Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate Cream In The Superficial Varicose Veins Treatmenttreatment3withdrawn
NCT05735639
THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)prevention4recruiting
NCT02054325
Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veinstreatment4completed
NCT04441957
MechanO-Chemical Ablation Versus CompreSSionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02397226
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open SurgeryNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02462720
COMFORT: A Multicenter, Open-label, Randomized, Crossover Studytreatment4completed
NCT02944331
3-4 Year Outcomes Following Endovenous Steam Ablation for Venous InsufficiencyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03037827
The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser AblationNo drug interventionstreatmentNot Availablecompleted
NCT01428076
Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM)treatment1completed
NCT04933591
Impact of Treatment With VENARUS® on the Level of Monocyte Chemoattractant Protein 1 in Varicose Veins Bloodbasic_scienceNot Availablecompleted
NCT05840991
Effect of Short-term Compression Therapy After Thermal Ablation for Varicose VeinsNo drug interventionstreatmentNot Availablerecruiting
NCT02335580
Effect of Portal Vein Thrombosis on the Prognosis of Liver CirrhosisNot AvailableNot Availablecompleted
NCT05058989
The Evaluation of the Pathophysiology of Varicose Veins in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT02046967
Steam Ablation Versus Endovenous Laser Ablation for the Treatment of Great Saphenous VeinsNo drug interventionstreatmentNot Availablecompleted
NCT04146168
Lake Washington Vascular VenaSeal™ Post-Market EvaluationNo drug interventionsNot AvailableNot Availableunknown_status
NCT05707169
Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose VeintreatmentNot Availableactive_not_recruiting
NCT02304146
Long-term Ultrasound Guided Foam Sclerotherapy Versus Classical Surgical Stripping StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT05372146
Great Saphenous Vein Sparing Segmental Radiofrequency Ablation in Varicose Veins PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02627846
Laser Ablation Versus Mechanochemical Ablation Trialtreatment4completed
NCT05380895
Comparison of Daytime Surgery in Varicose Veins Patients With and Without Superficial Venous ThrombosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03856814
Market Penetration of Laser Therapy in Venous Surgery: Ziekenhuis Oost-Limburg - Ziekenhuis Maas En Kempen Center ExperienceNo drug interventionsNot AvailableNot Availablecompleted
NCT00618514
The BRILLIANT StudyNo drug interventionsNot AvailableNot Availableterminated
NCT03384355
Ecchymosis and Coldness in Patients With Varicose VeinNo drug interventionsNot AvailableNot Availableunknown_status
NCT01195623
The Long-term Value of Preoperative Duplex Before Surgery for Varicose VeinsNo drug interventionsdiagnosticNot Availablecompleted
NCT01332838
A Comparison of Specialized Versus Standard Compression After Saphenous AblationNo drug interventionssupportive_careNot Availableunknown_status
NCT03685838
Compression Stockings Therapy Following Mechano-Chemical Ablation (Clarivein®)No drug interventionstreatmentNot Availableunknown_status
NCT04203043
The Prevstain Trialtreatment2unknown_status
NCT00928421
An Open-label, Single-dose Pilot Study to Evaluate Varisolve® (Polidocanol Endovenous Microfoam (PEM)) 0.125% [0.2%] for Varicose Veinstreatment2completed
NCT02504684
Treatment of Saphenous Vein Reflux With 1920-nm Diode LaserNo drug interventionstreatmentNot Availablecompleted
NCT06332833
Availability of Venous Conduits in Patients With Varicose Veins for Arterial Bypass SurgeryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03392753
Mechanochemical Ablation Compared to Cyanoacrylate AdhesiveNo drug interventionstreatmentNot Availablecompleted
NCT01072877
Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction (SFJ) Incompetencetreatment3completed
NCT06271798
Effect Of Resistive Exercises Versus Aerobic Exercises On Varicose Veins In Postmenopausal WomenNo drug interventionstreatmentNot Availablecompleted
NCT03041805
Caprini Score in Venous Surgery: a Prospective Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01203397
Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate In The Superficial Varicose Veins Treatmenttreatment3withdrawn
NCT00702897
Ambulatory Surgery of Lower Extremity Varicose VeinNo drug interventionsNot AvailableNot Availableunknown_status
NCT00841178
Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCTNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01949207
RCT - Does Treating Incompetent Perforators Reduce Recurrence?No drug interventionstreatmentNot Availableunknown_status
NCT04479956
Microwave Venous Ablation in Comparison to Radiofrequency Ablation, Laser Ablation and Surgical Ligation in Management of Great Saphenous Vein IncompetenceNo drug interventionstreatmentNot Availableunknown_status
NCT02139085
Great Saphenous Vein ElectrocoagulationNo drug interventionstreatment2unknown_status
NCT02657252
Polidocanol Versus Glucose Treatment of Telangiectasia Trialtreatment4completed
NCT04231942
Elastic Compression Stockings and Varicose Veins RecurrenceNo drug interventionstreatmentNot Availablerecruiting
NCT02557542
Pilot RCT Evaluating a One Stop Vein Clinichealth_services_researchNot Availableterminated
NCT02655406
COmpressioN Following Endovenous TreatmenT of Incompetent Varicose VeinsNo drug interventionstreatmentNot Availablecompleted
NCT03416413
Study of Foam Sclerotherapy Versus Ambulatory PhlebectomyNo drug interventionstreatment4recruiting
NCT02345018
Primary Insufficiency of the GSV With a Diameter >/= 12 mm, Antero-lateral Branches, or Below the KneeNo drug interventionsNot AvailableNot Availablecompleted
NCT03326219
Endoveneous Histologic StudyNo drug interventionsdiagnosticNot Availablewithdrawn
NCT01173419
Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous VeinNo drug interventionstreatmentNot Availablewithdrawn
NCT04671641
Endovenous Radiofrequency Ablation Closure System in the Treatment of Varicose VeinsNo drug interventionstreatmentNot Availableunknown_status
NCT04036734
Longitudinal or Transverse Orientation of Ultrasound Probe in Minimally Invasive Venous Surgery.No drug interventionstreatmentNot Availablecompleted
NCT01909024
Pelvic Embolisation to Reduce Recurrent Varicose Veins - RecurrentNo drug interventionstreatmentNot Availableunknown_status
NCT01611324
Painless Local Infiltration Anesthesiatreatment4completed
NCT02890563
Compression Therapy Following Truncal Vein Endothermal Ablation And Distal SclerotherapyNo drug interventionstreatmentNot Availablecompleted
NCT02051439
The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower LimbNo drug interventionsdiagnosticNot Availablecompleted
NCT06456125
Safety and Efficacy Of Amber Peripheral Liquid Embolic SystemNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02558426
Estrogen Receptors and Chronic Venous DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00430326
Juvista (Avotermin) in Scars Following Varicose Vein Removalprevention2completed
NCT04434274
MIcronized Flavonoid Fraction After MechanO-Chemical AblationNo drug interventionsNot AvailableNot Availableunknown_status
NCT00758420
Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetencetreatment2 / 3completed
NCT01901731
Pelvic Embolisation to Reduce Recurrent Varicose Veins - PrimaryNo drug interventionstreatmentNot Availableunknown_status
NCT01231373
Polidocanol Endovenous Microfoam (PEM) Versus Vehicle for the Treatment of Saphenofemoral Junction (SFJ) Incompetencetreatment3completed
NCT06290973
Quality of Life and Health Perception After Surgery of Varicose VeinsNo drug interventionsNot AvailableNot Availablecompleted
NCT05650073
A Study of Soundscapes for Patient WellbeingNo drug interventionssupportive_careNot Availableenrolling_by_invitation
NCT03477227
New Compression Hosiery Versus Standard Class II Compression Stockings After Endothermal AblationNo drug interventionstreatmentNot Availablecompleted
NCT02870127
Clinical Investigation and Molecular Forms of Family Disease of VaricoseNo drug interventionsNot AvailableNot Availablecompleted
NCT03613376
Compression And Functional Ability After Endovenous Varicose Vein TreatmentNo drug interventionstreatmentNot Availablecompleted
NCT00621062
Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein IncompetenceNo drug interventionstreatmentNot Availablecompleted
NCT00954980
Evaluation of Endovenous Sclerotherapy for Treatment of Varicose VeinsNo drug interventionsNot AvailableNot Availablecompleted
NCT04034329
PREservation Versus Thermal AblationNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04054440
Outpatient Office Based Endovascular ProceduresNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03057067
Embolization of Pelvic Varicosities in Patients With Pelvic Congestion SyndromeNo drug interventionstreatmentNot Availableterminated
NCT02867501
Venous Distension in Patients With Aneurysmatic Arterial DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03893201
A Singapore Venaseal Real World Post-Market Evaluation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06192472
Investigation Into the Pathophysiology and Treatment of Varicose Veinsbasic_scienceNot Availablecompleted
NCT03601572
Hypnoanalgesia in Surgical and Endovenous Treatment of VaricosisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00500669
A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgerytreatment3terminated
NCT05261412
Varicose Vein Education and Informed coNsent (VVEIN) StudyNo drug interventionshealth_services_researchNot Availablecompleted
NCT05410912
Varicose Vein in Patients Under the Age of 40No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05508581
Microwaves Ablation of Varicose VeinsNo drug interventionstreatmentNot Availablecompleted
NCT01637181
Clinical Trial of Endovenous 940 and 1470 Laser Ablation for Treating Great Saphenous VeinsNo drug interventionstreatmentNot Availablecompleted
NCT02441881
Trial of Radiofrequency Thermo-ablation Treatments of Great Saphenous Varicose Veins (3-RF Study)No drug interventionstreatmentNot Availablecompleted
NCT05122195
Graduated Elastic compRession for vAricose Veins in PrEgnancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01993914
Prevalence of MTHFR Polymorphisms in Venous DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02010723
Surgery Versus Sclerotherapy for Isolated Accessory Great Saphenous Vein VaricosisNo drug interventionstreatment4completed
NCT02676908
Optimum Duration of Compression Stockings After Endovenous Varicose Vein SurgeryNo drug interventionssupportive_careNot Availableunknown_status
NCT02241707
Does Minimal Post-operative Compression Affect the Outcome for Endovenous Ablation in Treating Varicose Vein Patients?No drug interventionsNot AvailableNot Availablewithdrawn
NCT00712517
Propofol Versus Volatile Anesthesia in Post Operative Pain ManagementpreventionNot Availableterminated
NCT02846051
Effect of Intensive Sports Practice on Lower Limb Varicose VeinsNo drug interventionsscreeningNot Availablecompleted
NCT02346058
Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose VeinsNo drug interventionstreatment4completed
NCT00529672
Surgery or Noninvasive Therapy for Varicose VeinsNo drug interventionstreatment3unknown_status