Fabry's Disease (DBCOND0028300)

Identifiers

Synonyms
Fabry / Fabry´s Disease / Fabry Disease / Fabry's disease / Fabry (-Anderson) disease / Angiokeratoma corporis diffusum universale / Deficiency of alpha-galactosidase (disorder) / Alpha galactosidase A deficiency / Fabry's disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Agalsidase alfa
A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
Agalsidase beta
A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
Migalastat
An alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
Pegunigalsidase alfa
A recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03362645
Diagnostic Value of the Electrocardiogram in Fabry DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT04724083
Inflammatory Pathways and Cardiac Growth Factors Associated With Fabry Disease CardiomyopathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00437944
Relation Between Polymorphism in Genes Related to Kidney Disease and Renal Manifistations in Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01268241
The Efficacy and Safety of Switch Between Agalsidase Beta to Agalsidase Alfa for Enzyme Replacement in Patients With Anderson-Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05206773
A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Diseasetreatment3recruiting
NCT05280548
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Diseasetreatment3recruiting
NCT05368038
ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening ProgramNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02994303
Podocyturia - Predictor of Renal Dysfunction in Fabry NephropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00097890
Replagal Enzyme Replacement Therapy for Adults With Fabry Diseasetreatment4completed
NCT03362164
Evaluation of HEArt invoLvement in Patients With FABRY DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00140621
A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Diseasetreatment4completed
NCT05046379
Studying Lipids as Potential Biomarkers in Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01650779
A Study Evaluating Glycosphingolipid Clearance in Patients Treated With Agalsidase Alfa Who Switch to Agalsidase Betatreatment4completed
NCT03145779
Evaluation of Phenotypic Variability in Fabry DiseaseNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05054387
China Post-marketing Surveillance (PMS) Study of Fabrazyme®treatment4completed
NCT00864851
Safety and Efficacy Study of Several Replagal Dosing Regimens on Cardiac Function in Adults With Fabry Diseasetreatment3completed
NCT00071877
An Open-Label Clinical Trial of Replagal Enzyme Therapy in Children Ages 7-17 Years With Fabry Diseasetreatment2completed
NCT01304277
This Study is Designed to Evaluate PD/PK and Safety of Replagal Manufactured by Two Different Processes.other2completed
NCT03596398
Epidemiological Study of Fabry Disease in Taiwan Young Stroke PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06065605
Assess Urine Biomarkers to Predict Nephropathy in Fabry DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT01165697
Establishment of Biomarkers for Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03135197
German Observational Multicenter Study of Patients With Fabry Disease Under Chaperone Therapy With Migalastat-HCl.No drug interventionsNot AvailableNot Availablecompleted
NCT00081497
A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Diseasetreatment4completed
NCT01695161
Non-invasive Assessment of Intraocular Pressure in MPS by Use of the Ocular Response Analyzer.No drug interventionsNot AvailableNot Availableunknown_status
NCT01632111
Pulmonary Involvement in Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03454893
Open Label, Study Of Efficacy and Safety Of AVR-RD-01 for Treatment-Naive Subjects With Classic Fabry Diseasetreatment1 / 2terminated
NCT02995993
Pharmacokinetics, Pharmacodynamics, and Safety of Moss-aGalactosidase A in Patients With Fabry Diseasebasic_science1completed
NCT01196871
Drug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabry Diseasetreatment2completed
NCT06325488
Fibrosis, Inflammation, Oxygenation of Renal Tissue In FabrY DiseaseNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00701415
A Study of Two Fabrazyme (Agalsidase Beta) Dosing Regimens in Treatment-naïve, Male Pediatric Patients Without Severe Symptomstreatment3completed
NCT03838237
Effect of Migalastat on Cardiac Involvement in Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04050137
Therapeutic Exercise to Treat Neuropathic PainNo drug interventionstreatmentNot Availablecompleted
NCT06065852
National Registry of Rare Kidney DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06207552
Evaluation of the Safety, Tolerability and Efficacy of a Gene Therapy Drug for the Treatment of Pediatric Fabry DiseaseNo drug interventionstreatment0recruiting
NCT06052800
Agalsidase Beta Long-Term Treatment Outcome for Fabry Disease Patients With IVS4 Mutation in TaiwanNo drug interventionsNot AvailableNot Availablerecruiting
NCT02969200
Fabry: Renal Function During Long-term ERT by 51Cr-EDTA ClearanceNot AvailableNot Availablecompleted
NCT04856059
Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparametric MRINo drug interventionsdiagnosticNot Availablerecruiting
NCT04999059
Long-Term Follow-up Study of Subjects With Fabry Disease Who Received Lentiviral Gene Therapy in Study AVRO-RD-01-201No drug interventionsNot AvailableNot Availableterminated
NCT01304875
Pulmonary Disease and Exercise Tolerance in Boys With Fabry DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02800070
Autologous Stem Cell Transplantation of Cells Engineered to Express Alpha-Galactosidase A in Patients With Fabry Diseasetreatment1completed
NCT00233870
A Long Term Safety and Efficacy Study of Fabrazyme Replacement Therapy in Japanese Patients With Fabry Disease.Not AvailableNot Availablecompleted
NCT00048906
Alpha-Galactosidase A Replacement Therapy for Fabry Diseasetreatment2completed
NCT04974749
A Study of REPLAGAL® in Treatment-naive Chinese Participants With Fabry Diseasetreatment3completed
NCT05056636
Epidemiological Study of Fabry Disease Screening in Chronic Kidney Disease PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06095713
German Observational Multicenter Study of Patients With Fabry Disease Under Enzyme Replacement Therapy With Pegunigalsidase-alfaNot AvailableNot Availablerecruiting
NCT01458119
Open-Label Phase 3 Long-Term Safety Study of Migalastattreatment3terminated
NCT03566017
Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry Diseasetreatment3active_not_recruiting
NCT05761834
FASHION Fabry Disease Hypertrophic Cardiomyopathy and InfammationNo drug interventionsNot AvailableNot Availablerecruiting
NCT01947634
Sleepiness and Sleep-disordered Breathing in Fabry Disease. A Prospective Cohort Study.No drug interventionsdiagnosticNot Availablecompleted
NCT00030134
Data Collection in Women With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04046224
Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)treatment1 / 2active_not_recruiting
NCT01581424
Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05843916
Switch Over Study of Biosimilar AGA for Fabry Diseasetreatment3recruiting
NCT01210196
Sophisticated Assessment of Disease Burden in Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06169358
Screening Patients With Fabry Disease in Patients With Hypertrophic Cardiomyopathy or Left Ventricular HypertrophyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02859363
Fabry Disease in Cerebrovascular DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01476163
Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry DiseaseNot AvailableNot Availableapproved_for_marketing
NCT00357786
An Open-Label Maintenance Study of the Enzyme Replacement Therapy Replagal in Patients With Fabry Diseasetreatment1completed
NCT02023086
Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry PatientsNot AvailableNot Availablecompleted
NCT04184986
Screening of Fabry Disease in Patients With GI SymptomsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00487630
Evaluation of Efficacy and Safety of Agalsidase Beta in Heterozygous Females for Fabry Diseasetreatment4unknown_status
NCT01839526
A Study of Renal Function in Treatment-naïve, Young Male Patients With Fabry Diseasebasic_science1terminated
NCT06303466
Real World Evidence Study of Danish Fabry PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03683966
MigALastat Therapy Adherence Among FABRY Patients: A Prospective Multicentral Observational StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04252066
A Global Prospective Observational Study of Women With Fabry Disease and Their Infants During Pregnancy and BreastfeedingNot AvailableNot Availablerecruiting
NCT00001774
Vasodilation in Patients With Fabry's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03949920
A Study of Migalastat in Fabry DiseaseNot AvailableNot Availableactive_not_recruiting
NCT05413876
Fabry Exercise Intolerance StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02795676
Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Functiontreatment3completed
NCT02228460
Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry DiseaseNo drug interventionstreatment2completed
NCT03500094
Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to <18 Years)treatment3completed
NCT04943991
Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical ScoreNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT00446862
The Fabrazyme® and Arbs and ACE Inhibitor Treatment (FAACET) StudyNot AvailableNot Availablecompleted
NCT06114329
Study of the Safety and Biologic Activity of AL01211 in Treatment Naive Males With Classic Fabry Diseasetreatment2recruiting
NCT01997489
Ophthalmic Findings During 10-year Enzyme Substitution of Danish Fabry Patients.treatment4completed
NCT04893889
Substudy (NCT04456582): Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Two-dimensional Shear Wave Elastography) in Patients With Amyloidosis and Fabry Disease.No drug interventionsdiagnosticNot Availableunknown_status
NCT01363492
Safety Study of Replagal® Therapy in Children With Fabry Diseasetreatment2completed
NCT02489344
Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Naïve Adult Male Patients With Fabry DiseaseNo drug interventionstreatment2completed
NCT00075244
Alternative Dosing and Regimen of Replagal to Treat Fabry Diseasetreatment2completed
NCT03180840
Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weekstreatment3completed
NCT03228940
Safety and Effect of Oral RVX000222 in Subjects With Fabry Diseasetreatment1 / 2withdrawn
NCT00312767
A Study in Patients With Fabry Disease Who Are on Chronic Hemodialysis Therapy for Treatment of End-stage Renal Insufficiency.treatment4withdrawn
NCT05710367
Effects Of Sodium Glucose Cotranspoter 2 Inhibitors On Heart And Kidneys In Fabry Disease Patientstreatment2not_yet_recruiting
NCT04025801
Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased IndividualsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04189601
Complement Activation in the Lysosomal Storage DisordersNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06007768
Autoimmune and Inflammatory Response Biomarkers in Fabry DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT05409846
Screening of Fabry Disease in Portuguese Patients With Idiopathic CardiomyopathiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02985710
Assessment of Small Fiber Neuropathy in Rare Diseases Using SudoscanNo drug interventionsdiagnosticNot Availablecompleted
NCT03886714
Screening for Fabry Disease in Renal TransplantationNo drug interventionsNot AvailableNot Availablerecruiting
NCT03737214
A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Diseasetreatment3active_not_recruiting
NCT01588314
Safety and Efficacy of Gabapentin for Neuropathic Pain in Fabry Diseasetreatment2withdrawn
NCT04020055
A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Diseasetreatment3recruiting
NCT03305250
Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry DiseaseNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT03123523
Study of the Relation Between Lipid Myocardial Overload Evaluated by Cardiac Magnetic Resonance Imaging (MRI), Alteration of Longitudinal Myocardial Deformations by Echocardiography, and Clinical Achievements (Functional, Biological and Electrical) in Fabry Disease, and Its Outcomes.No drug interventionsNot AvailableNot Availableunknown_status
NCT02090608
Paricalcitol in Fabry DiseasetreatmentNot Availablecompleted
NCT01295008
Androgenetic Alopecia in Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05106764
Early Detection of Fabry DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04602364
French Prospective, Observational Cohort Study of Patients With Fabry Disease Treated With MigalastatNo drug interventionsNot AvailableNot Availablecompleted
NCT00084084
Replagal Enzyme Replacement Therapy for Children With Fabry Diseasetreatment2completed
NCT00074984
A Study of the Safety and Efficacy of Fabrazyme (Agalsidase Beta) as Compared to Placebo in Patients With Advanced Fabry Diseasetreatment4completed
NCT00283933
A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Diseasetreatment2completed
NCT04440254
Long Duration Holter ECG in Fabry DiseaseNo drug interventionsscreeningNot Availablenot_yet_recruiting
NCT00343577
Antiproteinuric Agents and Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04916977
Global Burden and Treatment Trajectiories in Italian Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01678898
Dose-ranging Study of PRX-102 in Adult Fabry Disease Patientstreatment1 / 2completed
NCT01374997
Detection of Fabry Disease in Chronic Renal Failure Patients in Area Provence - Alpes - Côte d'AzurNo drug interventionsdiagnosticNot Availablecompleted
NCT00871611
Viennese Prevalence Study of Anderson-Fabry DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT00005111
PET Scans in Normal Volunteers and Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00526071
Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Studytreatment2terminated
NCT00074971
A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Diseasetreatment3completed
NCT06484478
A Real-world Wearables Study in Fabry Disease.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04073888
Study of the Spermatic Characteristics of Patients With Fabry DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT05923788
T1 Mapping in Fabry DiseaseNo drug interventionsdiagnosticNot Availablerecruiting
NCT00068107
Dosing Study of Replagal in Patients With Fabry Diseasetreatment2completed
NCT00230607
Study of the Effects of Fabrazyme Treatment on Lactation and Infantstreatment4terminated
NCT01745185
Immune Response in Subjects With Fabry Disease Who Are Switching From Agalsidase Alfa to Agalsidase BetaNo drug interventionsNot AvailableNot Availablecompleted
NCT02194985
Open-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry Diseasetreatment3completed
NCT05343715
PK/PD Study of 2 Agalsidase Formulations in Single Dose of 1 mg/kg Administered to Healthy Volunteers as IV Infusiontreatment1completed
NCT05473637
Taiwan Associated Genetic and Nongenetic Small Vessel DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT04281537
A Study to Describe the Experience of Both Patients and Their Clinicians in the Treatment of Fabry Disease With Enzyme Replacement Therapy.Not AvailableNot Availablecompleted
NCT01853852
A Phase I, Randomized, Single-Blind, Four-Period Cross-Over, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Single Oral Doses of GR181413A/AT1001 in Healthy Japanese SubjectsNo drug interventionsNot Available1completed
NCT00214500
A Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Diseasetreatment2completed
NCT00283959
A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Diseasetreatment2completed
NCT01218659
Study to Compare the Efficacy and Safety of Oral AT1001 and Enzyme Replacement Therapy in Patients With Fabry Diseasetreatment3completed
NCT05629559
4D-310 in Adults With Fabry Disease and Cardiac Involvementtreatment1 / 2active_not_recruiting
NCT04577170
Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05671770
Study Based on Electronic Health RecOrds to Identify Patients at High-risk of Fabry DiseasE (HOPE Fabry)No drug interventionsNot AvailableNot Availablecompleted
NCT00196742
Fabry Disease Registry & Pregnancy Sub-registryNo drug interventionsNot AvailableNot Availablerecruiting
NCT04639999
Impact of MIgalastat TheRApy on CaRdiac Function in patiEnts With Fabry's Cardiomyopathy (MIRACRE-Fabry Trial)No drug interventionsNot AvailableNot Availablerecruiting
NCT04519749
An Open-label, Phase 1/2 Trial of Gene Therapy 4D-310 in Adults With Fabry Diseasetreatment1 / 2active_not_recruiting
NCT04040049
A Fabry Disease Gene Therapy StudyNo drug interventionstreatment1 / 2terminated
NCT03230149
Prevalence and Characteristics of Fabry Disease (FD) in Patients With Stroke or Small Fiber NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00149318
Enzyme Replacement Therapy in Fabry DiseaseNo drug interventionsNot AvailableNot Availableterminated
NCT01298141
A Multicenter Open-Label Treatment Protocol to Observe the Safety of Replagal (Agalsidase Alfa) Enzyme Replacement Therapy in Canadian Patients With Fabry Diseasetreatment3completed
NCT02843334
Study of the Prevalence of Fabry Disease in French Dialysis PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03614234
Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patientstreatment3active_not_recruiting
NCT03678324
Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry DiseaseNo drug interventionsbasic_scienceNot Availablecompleted
NCT02908724
Cardiac Involvement in Adult Patients With Fabry Disease; Relation to Enzyme Replacement TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT06539624
Evaluate the Safety and Preliminary Efficacy of EXG110 in Subjects With Fabry DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00837824
Severe Renal Disease Study in Fabry Patients Treated With Fabrazymetreatment2terminated
NCT05186324
Fabry Patient's Experience Of PegunigaLsidasE Alfa Monthly InfusionNo drug interventionsNot AvailableNot Availablecompleted
NCT06270316
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry DiseaseNo drug interventionstreatment1 / 2recruiting
NCT00196716
A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Diseasetreatment2completed
NCT00055016
Registry of Fabry Disease - A Multicenter Observational StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00074958
A Study of Fabrazyme in Pediatric Patients With Fabry Diseasetreatment2completed
NCT04143958
To Assess the Glycosphingolipid Clearance and Clinical Effects of Switching to Agalsidase Beta (Fabrazyme) Versus Continuing on Agalsidase Alfa (Replagal) in Male Patients With Classic Fabry Diseasetreatment4withdrawn
NCT02120235
Investigating Lysosomal Storage Diseases in Minority GroupsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03425539
Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Diseasetreatment3completed
NCT04455230
A Long Term Follow-Up Study of Fabry Disease Subjects Treated With FLT190No drug interventionsother1 / 2completed
NCT03018730
Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)treatment3completed
NCT04758130
Getting Global Rare Disease Insights Through Technology StudyNo drug interventionsotherNot Availableunknown_status
NCT04804566
Understanding Fabry Disease Therapy Choices Through the Eyes of the PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05039866
Long-Term Follow-up of Subjects Who Were Treated With ST-920Not AvailableNot Availableenrolling_by_invitation
NCT05699265
Cardiovasculorenal Phenotyping in Fabry Disease Through Noninvasive TestingNo drug interventionsNot AvailableNot Availablerecruiting
NCT03289065
Fabry Outcome Survey (FOS)No drug interventionsNot AvailableNot Availablecompleted
NCT00168974
Neuropathic Pain and Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01981720
Extension Study of PRX-102 for up to 60 Monthstreatment1 / 2completed
NCT02921620
Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry Diseasetreatment3withdrawn
NCT01730482
A Study to Assess the Absorption, Metabolism and Excretion of Migalastat Hydrochloride (AT1001-014)No drug interventionstreatment1completed
NCT01031173
Treatment Protocol of Replagal for Patients With Fabry DiseaseNot AvailableNot Availableno_longer_available
NCT04043273
Treatment-related Benefit and Satisfaction in Fabry Patients. Insight in Patients Expectations and PreferencesNo drug interventionsNot AvailableNot Availablecompleted
NCT02082327
A Phase 1 Study To Evaluate the Safety of Migalastat Hydrochloride Given Intravenously to Healthy Volunteerstreatment1completed
NCT05679076
A Qualitative Study on the Pain and Quality of Life of Patients With Fabry DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02649660
Lipidomics and Functional Analyses of Platelets in Fabry DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT04049760
Safety, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged >12 Years) With Fabry Diseasetreatment3active_not_recruiting
NCT04552691
Open-Label Expanded Access Treatment With Pegunigalsidase Alfa for Fabry Disease PatientsNot AvailableNot Availableapproved_for_marketing
NCT03230591
Impact of Agalsidase Alfa Therapy on Cardiac funcTION in Patients With Fabry's CardiomyopathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06081062
Evaluate the Safety and Efficacy of Fabagal® (Agalsidase Beta) in Patients With Fabry Diseasetreatment3recruiting
NCT01019629
Fabry Screening StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02152189
Screening for Fabry Disease in a Pediatric Population at RiskNo drug interventionsNot AvailableNot Availablecompleted
NCT05710692
Study to Evaluate the Safety, PK, PD, and Efficacy of PRX-102 in Japanese Patients With Fabry Diseasetreatment2 / 3recruiting
NCT01653444
Evaluate the Safety and Exploratory Efficacy of GC1119No drug interventionstreatment1completed
NCT04840667
A Study of Replagal in Treatment-naïve Adults With Fabry Diseasetreatment3terminated
NCT04965467
Fabry Aim Children Early (ACE) ProjectNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03199001
Native T1 Mapping by Cardiovascular Magnetic Resonance Imaging in Rare DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT06257901
A Co-designed Physical Activity Intervention in Fabry DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04708301
Characterisation of Heart Involvement in Fabry Disease With T1 MappingNo drug interventionsNot AvailableNot Availablecompleted
NCT05698901
Biomarkers and Cardiac Imaging Diagnostic Assay for Monitoring Patients With Fabry DiseaseNot AvailableNot Availablerecruiting
NCT00925301
Study of the Effects of Oral AT1001 (Migalastat Hydrochloride) in Patients With Fabry Diseasetreatment3completed
NCT03321604
Kidney Information Network for Disease Research and EducationNo drug interventionsNot AvailableNot Availableterminated
NCT00455104
Canadian Fabry Disease Initiative (CFDI) National RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05067868
A Study of Replagal in Children and Adults With Fabry Disease in Indiatreatment4active_not_recruiting
NCT01730469
Safety and Pharmacokinetics of AT1001 (Migalastat HCl) in Healthy Subjects and Subjects With Impaired Renal Functiontreatment1completed
NCT01355146
Home Therapy With Replagal in Fabry DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00304512
A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Female Participants With Fabry Diseasetreatment2completed
NCT00106912
Study to Collect Data on Fabry Disease Patients With Enhanceable Alpha-Galactosidase A ActivityNo drug interventionsNot AvailableNot Availablecompleted
NCT00413595
Stroke in Young Fabry Patients (sifap2): Characterization of the Stroke RehabilitationNo drug interventionsNot AvailableNot Availablecompleted
NCT01489995
Migalastat Food Effect Studytreatment1completed
NCT02930655
A Study to Assess the Safety and Tolerability of Lucerastat in Subjects With Fabry Diseasetreatment1completed
NCT06328608
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Diseasetreatment2 / 3not_yet_recruiting
NCT01124643
Extension Study of TKT028 Evaluating Safety and Clinical Outcomes of Replagal® in Adult Patients With Fabry Diseasetreatment3completed
NCT01769001
An Extension of a Phase 1/2, Open Label, Dose Ranging Study of PRX-102 in Adult Fabry Patientstreatment1 / 2completed
NCT01178164
Prevalence of Fabry's Disease in a Population of Patients With Chronic PainsNo drug interventionsdiagnosticNot Availablecompleted
NCT04847713
Early Detection and Follow-Up of Patients With Fabry's DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02469181
Impact of Enzyme Replacement Therapy on Cardiac Function in Patients With Fabry's Cardiomyopathy (RECAFTURE Trial)No drug interventionsNot AvailableNot Availablerecruiting
NCT06019728
A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazymetreatment4recruiting
NCT02798458
Evaluation of the Gastrointestinal Manifestation of Fabry's DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT02582294
Fabry's Disease and Pregnancy (PREFAB)No drug interventionsNot AvailableNot Availableterminated
NCT00001491
Analysis of the Nervous System in Patients With Fabry's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02450604
Prevalence of Fabry's Disease in a Population of Patients With Chronic PainNo drug interventionsdiagnosticNot Availablecompleted