Substance Dependence (DBCOND0030232)

Identifiers

Synonyms
Drug Dependence / Substance Dependency / Drug Dependency / Substance Use Dependence / Substance dependence / Unspecified drug dependence / Drug dependence, unspecified / Addiction to drugs / Dependent drug abuse (disorder) / Drug addiction / Dependence drug (NOS) / Drug dependence NOS / Psychoactive substance dependence (disorder) / Substance dependence (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Flupentixol
A thioxanthene neuroleptic used to treat schizophrenia and depression.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02130921
Enhancing the Role of Commune Health Workers in HIV and Drug Control: A Randomized Controlled TrialNo drug interventionspreventionNot Availablecompleted
NCT05440721
Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical VerificationNo drug interventionsbasic_scienceNot Availablewithdrawn
NCT02396979
Intervention of HIV, Drug Use and the Criminal Justice System in MalaysiaNo drug interventionstreatment4completed
NCT00605033
A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)No drug interventionstreatment4completed
NCT01171677
Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial DeficitsNo drug interventionstreatmentNot Availablecompleted
NCT00278447
Addiction Health Evaluation And Disease Management (AHEAD) StudyNo drug interventionstreatment3completed
NCT02656745
Clinical Trial of Smoking Cessation Mobile Phone ProgramNo drug interventionstreatmentNot Availablecompleted
NCT00675532
Testing a Primary Care Model for the Treatment of Opioid Dependence Using Long-acting Injectable Naltrexone (Vivitrol).No drug interventionstreatmentNot Availablewithdrawn
NCT02281175
How to Ease the Withdrawal of Tranquilizers Among Older Consumers?No drug interventionstreatmentNot Availablecompleted
NCT03539575
CB1R in Synthetic Psychoactive CannabinoidsNo drug interventionsotherNot Availableactive_not_recruiting
NCT04581499
Tech-Enabled CM for AUD at ScaleNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00876941
Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug UseNo drug interventionstreatment3completed
NCT01550341
HIV, Buprenorphine, and the Criminal Justice SystemtreatmentNot Availablecompleted
NCT00882648
The Effect of Fetal Gender on Maternal Substance Abuse TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT04003948
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone DetoxificationNo drug interventionstreatment2unknown_status
NCT00005765
Behavioral Economics of Human Drug Self-AdministrationNot AvailableNot Availablecompleted
NCT02124980
Automated Recovery Line for Medication Assisted TreatmentNo drug interventionstreatmentNot Availablecompleted
NCT02543944
Improving Treatment Outcomes for Prescription Opioid DependenceNo drug interventionstreatment2 / 3completed
NCT01246401
Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice PopulationsNo drug interventionstreatment1 / 2completed
NCT00706901
Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed VeteransNo drug interventionstreatmentNot Availablecompleted
NCT00265512
LINK: Aftercare Monitoring ProjectNo drug interventionstreatmentNot Availablecompleted
NCT04141202
Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use DisorderNo drug interventionsNot AvailableNot Availablerecruiting
NCT03678051
CBT4CBT for Women in Residential Treatment for Substance Use DisordersNo drug interventionstreatmentNot Availablecompleted
NCT01068847
Drug Discrimination in Methadone-Maintained Humans Study 3No drug interventionsbasic_science1completed
NCT00604188
A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED)No drug interventionstreatment4completed
NCT01052675
Pharmacological, Clinical and Statistical Assessment of a New Tool Available for Pharmacodependence Report EvaluationNo drug interventionsNot AvailableNot Availablecompleted
NCT01338506
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use DisordersNo drug interventionstreatmentNot Availablecompleted
NCT00183118
Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment)No drug interventionsprevention1 / 2completed
NCT02173041
Impact of Prevention Awareness Group (PAG) on Treatment Attendance and Drug Abstinence Among Substance UserNo drug interventionstreatmentNot Availablecompleted
NCT02564341
Targeting Effective Analgesia in Clinics for HIV - InterventionNo drug interventionshealth_services_researchNot Availablecompleted
NCT04709016
Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUMENo drug interventionsNot AvailableNot Availablecompleted
NCT00975416
Oxytocin and Cognitive Behavioral Therapy in Drug DependenceNo drug interventionstreatment4terminated
NCT01382316
Making Alcoholics Anonymous EasierNo drug interventionstreatment3completed
NCT00593463
Drug Discrimination in Methadone-Maintained Humans Study 1No drug interventionsNot Available1completed
NCT01036126
Automatic Versus Evaluative Components of Cue ReactivityNo drug interventionsNot AvailableNot Availablecompleted
NCT00047866
Brain Function in Response to Motivational StimuliNo drug interventionsNot AvailableNot Availablecompleted
NCT00367874
Treatment of Polydrug-Using Opiate Dependents During WithdrawalNo drug interventionstreatment4completed
NCT02525731
Targeting Effective Analgesia in Clinics for HIV - Patient CohortNo drug interventionsNot AvailableNot Availablecompleted
NCT03694327
Innovative Digital Therapeutic for Smoking CessationNo drug interventionstreatmentNot Availablecompleted
NCT03333460
Transcranial Magnetic Stimulation for Cocaine AddictionNo drug interventionstreatmentNot Availableunknown_status
NCT00579267
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)No drug interventionsNot AvailableNot Availablecompleted
NCT01449981
Development and Testing of Adolescent Twelve-Step FacilitationNo drug interventionstreatmentNot Availablecompleted
NCT00260481
Prometa Pharmacotherapy for Methamphetamine DependenceNo drug interventionstreatment2 / 3completed
NCT01096550
Intensive Outpatient Versus Outpatient Treatment With Buprenorphine Among African AmericansNo drug interventionstreatmentNot Availablecompleted
NCT01843023
Extended Release Naltrexone for Opioid-Dependent YouthNo drug interventionstreatment4completed
NCT02224508
Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy RisksNo drug interventionsNot AvailableNot Availablecompleted
NCT00798538
Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)No drug interventionshealth_services_research4completed
NCT03583138
HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)No drug interventionsNot AvailableNot Availablecompleted
NCT02119949
Working Memory Training for Substance Dependent IndividualsNo drug interventionstreatmentNot Availablecompleted
NCT00208143
Seroquel Therapy for Substance Use Disorders Comorbid With SchizophreniaNo drug interventionstreatment4completed
NCT05679284
A Cross-Sectional Observational Study on Retained Drug Needle Fragments in People Who Use Intravenous DrugsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00513279
To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334No drug interventionstreatment1completed
NCT00057187
Improving Substance Abuse Treatment Aftercare Adherence and OutcomeNo drug interventionstreatmentNot Availablecompleted
NCT01381133
Adolescent Outpatient and Continuing Care StudyNo drug interventionstreatment3completed
NCT03762798
Can The Bridge Transition Opiate Use Disorder Patients in Stable Recovery From Buprenorphine to NaltrexoneNo drug interventionstreatmentNot Availablewithdrawn
NCT00728897
A Healthy Volunteer Study to Investigate the Relative Bioavailability of Two Forms of GSK598809 Capsules.No drug interventionstreatment1completed
NCT01036061
GSK618334 Repeat Dose StudyNo drug interventionsother1completed
NCT01621711
Continuing Care Following Drug Abuse Treatment: Linkage With Primary CareNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT01011907
A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependencebasic_scienceNot Availablecompleted
NCT00437632
Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809No drug interventionstreatment1completed
NCT02461732
Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance DependenceNo drug interventionstreatmentNot Availablecompleted
NCT05833399
Correlation of Genetic Variations With Clinical Response in Substance Use DisorderNot AvailableNot Availablerecruiting
NCT01189799
Motivational Therapy for Substance Users With DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00908206
Effects of GSK598809 on Brain Activation in Abstinent AlcoholicsNo drug interventionstreatment1withdrawn
NCT00605241
A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine RewardNo drug interventionstreatment1completed
NCT05348317
Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use DisordersNo drug interventionstreatmentNot Availablerecruiting
NCT00606996
Group Therapy for Women Prisoners With Comorbid Substance Use and DepressionNo drug interventionstreatment2completed
NCT00295139
Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) PatientsNo drug interventionstreatmentNot Availablecompleted
NCT04430257
Pre-exposure Prophylaxis (PrEP) for HealthNo drug interventionspreventionNot Availablerecruiting
NCT00430482
Stress, Distress Intolerance, and Drug DependenceNo drug interventionstreatmentNot Availablecompleted
NCT01128140
Efficacy Trial of Warrior Check-UpNo drug interventionstreatment2completed
NCT01550887
Evaluation of Impulsivity on Cocaine and Crack AddictsNo drug interventionsdiagnosticNot Availablecompleted
NCT01039454
Effects of the D3 Antagonist GSK598809 on Food Reward and ReinforcementNo drug interventionstreatment1completed
NCT01634347
Memory Reconsolidation Blockade for Treating Drug AddictionNo drug interventionstreatment2completed
NCT00657397
Initialization of Methadone in Primary Care, Randomized Intervention Research for Preventing HCV Transmission PracticesNo drug interventionsprevention3completed
NCT00630097
A Dose Ranging Study of Modafinil for Methamphetamine DependenceNo drug interventionstreatment2unknown_status
NCT05410561
Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT01314378
Effects of Intensive Behavioral Training Program on Impulsivity and Inhibitory Control in SmokersNo drug interventionstreatmentNot Availableunknown_status
NCT03767907
Online Cognitive Behavioural Therapy for Addiction: Efficacy and Cost-Effectiveness in a Pragmatic Clinical TrialNo drug interventionstreatmentNot Availablecompleted
NCT01741415
Distress Tolerance Treatment for Substance UsersNo drug interventionstreatment2unknown_status
NCT03048552
Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3No drug interventionshealth_services_researchNot Availablecompleted
NCT00728052
A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy SmokersNo drug interventionstreatment1completed
NCT05312359
Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance DependentsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03000699
Efficacy of Cognitive Bias Modification in Residential Treatment for AddictionNo drug interventionstreatmentNot Availablecompleted
NCT01515917
Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)No drug interventionstreatmentNot Availablewithdrawn
NCT00288886
Reinforcement of Abstinence and Continuing Care in Substance Abuse TreatmentNo drug interventionstreatment2completed
NCT01320748
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent AdultsNo drug interventionstreatmentNot Availablecompleted
NCT00814957
An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET LigandNo drug interventionstreatment1completed
NCT04768920
Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT01305629
Intervention Targeting Substance Using Older Adults With HIVNo drug interventionstreatmentNot Availablecompleted
NCT00609089
Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk ReductionNo drug interventionstreatment1 / 2unknown_status
NCT00484692
Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking CessationNo drug interventionstreatment4completed
NCT01155544
Improving Outcomes in Psychosis Associated With Substance Use Using AripiprazoleNo drug interventionstreatment4withdrawn
NCT00437840
A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809No drug interventionstreatment1completed
NCT00887367
EtOH Interaction StudyNo drug interventionstreatment1completed
NCT00793468
Relapse Prevention Study in Newly Abstinent SmokersNo drug interventionstreatment2withdrawn
NCT01410110
Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse TreatmentNo drug interventionstreatment2completed
NCT00208195
Depakote ER Therapy for Mania Comorbid With Substance AbuseNo drug interventionstreatment4completed
NCT00227838
Modifying Group Therapy for Bipolar Substance Abusers - 1No drug interventionstreatmentNot Availablecompleted
NCT01769651
Clinician-patient Interaction During Addiction ConsultationNo drug interventionsNot AvailableNot Availableunknown_status