Barrett's Esophagus (DBCOND0030309)

Identifiers

Synonyms
Barretts Esophagus / Barrett's oesophagus / Esophagus, Barrett / Barrett Oesophagus / Barrett Esophagus / Barret's esophagus / Barrett's esophagus / Barrett's esophagus without dysplasia / Barrett's oesophagitis / Barrett's esophagitis / Endobrachyoesophagus / Endobrachyooesophagus / Barrett's esophagus (disorder) / Ulcer of esophagus / Barrett's ulcer of esophagus (disorder) / Barrett's esophagus with esophagitis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Porfimer sodium
A hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00650988
Cryotherapy for Barrett's Esophagus and Early Esophageal CancersNo drug interventionstreatment0completed
NCT01733719
Barrett&Apos;s Intervention for Dysplasia by EndoscopyNo drug interventionshealth_services_researchNot Availablecompleted
NCT00586989
Endoscopic Tri-Modal Imaging in Patients With Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT02200250
Long Term Barrett's Endoscopic Mucosal Resection StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00737802
In Vivo Anatomy, Physiology, Mechanics and Function of the Lower Esophageal SphincterNo drug interventionsNot AvailableNot Availableterminated
NCT04155242
The Use of Biomarkers to Guide Management of Patients Treated With Radiofrequency Ablation for Early Oesophageal NeoplasiaNo drug interventionsdiagnosticNot Availablerecruiting
NCT02852161
The Accuracy and Acceptability of Magnet Assisted Capsule Endoscopy in the Diagnosis of Esophageal Pathology: a Pilot StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT02614703
"Acetic Acid Chromoendoscopy in Barrett's Esophagus Surveillancediagnostic2 / 3terminated
NCT01384864
Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasiascreening0completed
NCT05965921
Real-life Prospective Evaluation of Computer-aided Detection (CAD) of Barrett's NeoplasiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00587184
Confocal Microscopy in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT03418584
Application of hybridAPC in the Treatment of BarrettNo drug interventionstreatmentNot Availableunknown_status
NCT02793479
Radiofrequency Ablation in Patients With Barrett's EsophagusNo drug interventionsNot AvailableNot Availableunknown_status
NCT05645679
Efficacy and Safety of HYbrid Argon Plasma Coagulation Technique in Patients With Barrett's Esophagus-Related DysplasiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01236443
Study of Photodynamic Therapy (PDT) Using HPPH in Barrett's EsophagusNo drug interventionstreatment1completed
NCT01572987
Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's EsophagusNo drug interventionstreatmentNot Availableterminated
NCT01641887
Decision Aid for Gastroesophageal Reflux Disease ManagementNo drug interventionsNot AvailableNot Availableunknown_status
NCT02534233
Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal EpitheliumNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01439633
Optical Frequency Domain Imaging (OFDI) Surveillance and Image Guided Biopsy of the EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT01845454
A Dose-Optimization Study for the Initial Treatment of Dysplastic Barrett's Esophagus With trūFreeze™ Spray CryotherapyNo drug interventionstreatmentNot Availableterminated
NCT01976351
Imaging Enhanced Endoscopy for the Screening of Barrett's EsophagusNo drug interventionsNot AvailableNot Availableterminated
NCT01733147
Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acidstreatment4completed
NCT01630798
A In-Vivo Esophageal Protocol for Detection of Neoplasia in the Digestive Tractdiagnostic1completed
NCT01503411
High Resolution Optical Imaging of Barrett's Esophagus Using Nvision Volumetric Laser Endomicroscopy (VLE)No drug interventionsNot AvailableNot Availablecompleted
NCT01694511
Endoscopic Detection of Dysplasia in Barrett's EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT01633411
Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Barrett's EpitheliumNo drug interventionsNot AvailableNot Availablecompleted
NCT00573911
Acid Reflux and Stromal Fibroblasts in Barrett's EsophagusNo drug interventionsdiagnostic1completed
NCT02395471
Cytosponge Adequacy Study Evaluation IINo drug interventionsdiagnosticNot Availablecompleted
NCT01438385
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT00587600
Biomarkers in Phototherapy of Barrett's EsophagusNo drug interventionstreatment2 / 3completed
NCT00588575
Ramanspectroscopy in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT02249975
Efficacy of CryoBalloon Focal Ablation System on Human Esophageal Barrett's EpitheliumNo drug interventionstreatmentNot Availablecompleted
NCT01401699
Optical Coherence Tomography (OCT) Based Screening of Esophagus and Gastroesophageal JunctionNo drug interventionsotherNot Availablecompleted
NCT01442506
Acetic Acid Guided Biopsies Compared With High Definition Endoscopy in the Detection of Barrett's EsophagusNo drug interventionsNot AvailableNot Availableunknown_status
NCT01281618
Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT00288119
Genetic Determinants of Barrett's Esophagus and Esophageal AdenocarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02498041
The Efficacy and Patient Tolerance of Ultrathin Nasal Endoscopy to Detect Barrett's OesophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT01030263
A Trial Comparing Yield of Confocal Endomicroscopy Guided BiopsiesNo drug interventionsdiagnostic4terminated
NCT00526786
Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia Within Barrett's EsophagusNo drug interventionstreatment4terminated
NCT02210039
Using Spectrally Encoded Confocal Microscopy (SECM) to Visualise the Esophagus Using an SECM ProbeNo drug interventionsscreeningNot Availablecompleted
NCT00590239
Barrett's Esophagus Related Neoplasia (BERN) ProjectNo drug interventionsNot AvailableNot Availablerecruiting
NCT01484925
BETERNet Notch Signaling and Novel Biomarkers for Barretts EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT01373125
Is the Neosquamous Epithelium "Normal" Following Endoscopic Ablation of Dysplastic Barrett's Esophagus?No drug interventionsNot AvailableNot Availablecompleted
NCT02464930
Evaluation of MicroRNA Expression in Blood and Cytology for Detecting Barrett's Esophagus and Associated NeoplasiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01293448
Evaluation of Balloon-based Cryoablation of Human Esophageal EpitheliumNo drug interventionstreatmentNot Availablecompleted
NCT00546065
APE-Study: Ablation of Barrett's Mucosa vs. Surveillance Without Ablation in Patients Cured From Barrett's Cancer Combined With Randomization of Esomeprazole vs. Placebo for Symptomatic Reflux Control After Successful Barrett's AblationpreventionNot Availableterminated
NCT06523374
A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of CancerNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01572974
Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availableterminated
NCT02632682
Confocal Laser Endomicroscopy vs Conventional Histology for the Identification of Intestinal MetaplasiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00513331
Barrett's Esophagus & Gastroesophageal Reflux DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01580631
Narrow Band Imaging Project on Barrett's EsophagusNo drug interventionsNot AvailableNot Availablesuspended
NCT01384227
Evaluation of a Miniaturized Microscope Device for the Detection of Barrett's Neoplasia: A Pilot Studyscreening0completed
NCT02579460
Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-TransitionNo drug interventionsbasic_scienceNot Availablecompleted
NCT01439594
Optical Frequency Domain Imaging (OFDI) Assessment in Radiofrequency AblationNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT00943280
Barrett's Esophagus in Olmsted CountyNo drug interventionsNot AvailableNot Availablecompleted
NCT01188980
Early Increase in Blood Supply in Patients With Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT01084629
The Role of the Fujinon Intelligent Chromo Endoscopy (FICE™) in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT05740189
CBAS180 De-escalation StudyNo drug interventionstreatmentNot Availablerecruiting
NCT01032044
CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal NeoplasiaNo drug interventionsdiagnosticNot Availablecompleted
NCT04880044
Detection of Barrett s Esophagus in Patients Without GERD SymptomsNo drug interventionsscreeningNot Availablerecruiting
NCT01360801
High Definition White Light Endoscopy and Narrow Band Imaging for the Assessment of Barrett's Disease After Endoscopic TherapyNo drug interventionsNot AvailableNot Availableterminated
NCT02482701
The Captivator EMR RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT00586404
The Study of Barrett's Esophagus: What Are the Factors of ProgressionNo drug interventionsNot AvailableNot Availableterminated
NCT05818072
The Prevalence, Risk Factors and Optimal Biopsy Protocol of BENo drug interventionsdiagnosticNot Availablerecruiting
NCT00586872
Endoscopic Mucosal Resection (EMR) in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT00754468
Study of CryoSpray Ablation(TM)to Determine Treatment Effect, Depth of Injury, and Side Effects in the Esophagus.No drug interventionstreatment4completed
NCT02427269
University of North Carolina (UNC) Barrett's Esophagus and Esophageal Cancer BiorepositoryNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01288612
Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts EsophagusNo drug interventionsscreeningNot Availablecompleted
NCT03813381
CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO).No drug interventionstreatmentNot Availablecompleted
NCT02149914
The Changes of Ryodoraku and HRV After PPI Treatment in GERD PatientsscreeningNot Availableunknown_status
NCT00587314
The Effect of Ablation Therapy on Barrett's EsophagusNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00872755
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)No drug interventionstreatment4completed
NCT01093755
Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?treatment4completed
NCT01286155
Epidemiology of Barrett's Esophagus: A Population Based StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00909350
Micro-RNA (miR) Expression in Upper Gastrointestinal Mucosal TissueNo drug interventionsNot AvailableNot Availablecompleted
NCT02864043
Barrett's Dysplasia Detection Pilot Trial Using the NvisionVLE® Imaging SystemNo drug interventionsdiagnosticNot Availableunknown_status
NCT01787864
Prevalence of Dysplasia of the Gastric CardiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02879721
Expression and Function of the Renin-Angiotensin System in the Esophagusbasic_science0completed
NCT01905202
The Safety and Tolerability of Secretrol in Patients With Barrett's EsophagusNo drug interventionstreatment1unknown_status
NCT02513784
Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal MicrobiometreatmentNot Availablecompleted
NCT00628784
Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal CancerNo drug interventionstreatment4unknown_status
NCT00795184
Detection Of Neoplastic Tissue in Barrett's Esophagus With In vivO Probe-based Confocal EndomicroscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT02422433
Surveillance and Image-Guided Biopsy of the Esophagus Using an OFDI CapsuleNo drug interventionsotherNot Availableactive_not_recruiting
NCT02066233
Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard EndoscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT00081354
Early Detection of Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT00844077
Preliminary Longitudinal Validation of Biomarkers Predictive of Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT01477177
Polar Wand Carbon Dioxide Cryotherapy for Barrett's EsophagusNo drug interventionstreatmentNot Availableterminated
NCT02634645
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)No drug interventionsNot AvailableNot Availablerecruiting
NCT02075905
Stratifying Risk in Barrett's Esophagus: A Pilot Study for Biomarker-based Patient ManagementNo drug interventionsNot AvailableNot Availablecompleted
NCT04408105
Survey Study on Barrett's Esophagus ScreeningNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00352261
An Open Label pH Comparison of Esomeprazole and Lansoprazole in Barrett's Esophagus Patientstreatment4completed
NCT00591461
Study of Endoscopic Barrett's Esophagus DiagnosisNo drug interventionsNot AvailableNot Availableterminated
NCT03526328
DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett's Esophagus/Esophageal AdenocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02947971
Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging SystemNo drug interventionsotherNot Availablerecruiting
NCT01961778
Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early AdenocarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT00637988
Barrett's Esophagus - 315 - 3 Way Cross Overtreatment4completed
NCT00216788
The Effect of Nexium on Transmucosal Esophageal Leaktreatment1unknown_status
NCT00637559
Barrett's Esophagus - 315 - 3 Way Cross-Overtreatment4completed
NCT02033070
Patient Registry: Radio Frequency Ablation of Barrett's Esophagus Using HALO SystemNo drug interventionsNot AvailableNot Availableunknown_status
NCT01238042
Study To Determine The Maximum Range of Light Doses At Two HPPH Doses With Acceptable Normal Tissue Toxicity For PDT Treatment Of High Grade Dysplasia,CIS or Early Adenocarcinoma In Barrett's EsophagusNo drug interventionstreatment1completed
NCT01306799
To Learn How Bone Structure and Bone Mass Change After Long-term PPI UseNo drug interventionsNot AvailableNot Availablecompleted
NCT01298999
Trial of a Gastrin Receptor Antagonist in Barrett's Esophagusprevention2completed
NCT02922049
pCLE in the Detection of Esophageal and Gastric Lesions and Intestinal Metaplasia or Dysplasia in Patients After Endoscopic Treatment of BORNNo drug interventionsdiagnosticNot Availablecompleted
NCT00747136
WavSTAT® Optical Biopsy System to Target Esophageal BiopsiesNo drug interventionsNot AvailableNot Availableterminated
NCT03621319
Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation TechniqueNo drug interventionstreatmentNot Availableterminated
NCT02162758
Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency Ablationtreatment2terminated
NCT01203163
Case Analysis on Real Life Incidence of Photodynamic Therapy (PDT) Safety OutcomesNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02852525
Confocal Laser Probe to Treat Barrett's EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT00747448
CryoSpray Ablation (TM) GI Patient RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT01374074
Racial Disparity in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT01566474
Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Studyprevention3completed
NCT00574327
Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02198976
Australian Barrett's Cohort With Dysplasia and Early Cancer StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02018367
Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinomaother2unknown_status
NCT02066701
Gene Methylation in the Diagnosis of Barrett's Esophagus: Identification of Candidate Diagnostic MarkersNo drug interventionsNot AvailableNot Availablecompleted
NCT00885469
PillCam® ESO 2 in Esophageal PathologiesNo drug interventionsNot AvailableNot Availablecompleted
NCT02597712
YF476 in Barrett's Esophagustreatment2completed
NCT02106910
Non-Endoscopic Surveillance for Barrett's Esophagus Following Ablative TherapyNo drug interventionsdiagnosticNot Availablecompleted
NCT02230410
Cryo Balloon for Residual Barrett's EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT01384695
A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1screening0terminated
NCT00487695
Confocal Endomicroscopy for Barrett's EsophagusNo drug interventionsdiagnostic3completed
NCT02445014
Pilot Study to Image the Esophagus Using a SECM Tethered Endoscopic CapsuleNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT02204150
Study to Image the Esophagus Using the OFDI CapsuleNo drug interventionsdiagnosticNot Availablecompleted
NCT01568723
Betrnet Stem Cells and the Origins of Barrett's Esophagus Project 3 RF AblationNo drug interventionsNot AvailableNot Availablecompleted
NCT01913223
Endoscopic Sub-mucosal Dissection With the Nestis® Jet Injector System With a Bi-functional Catheter: First Prospective TrialNo drug interventionstreatmentNot Availablecompleted
NCT00058877
Familial Aggregation of Barrett's EsophagusNo drug interventionsNot AvailableNot Availableunknown_status
NCT02495051
Esophageal Atresia: Metaplasia, BarrettNo drug interventionsNot AvailableNot Availablecompleted
NCT06381583
A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal AdenocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01360541
Radiofrequency Ablation for Barrett Oesophagus With Low Grade DysplasiaNo drug interventionstreatment2completed
NCT05468008
Endoscopic Submucosal Dissection (ESD)No drug interventionsNot AvailableNot Availablerecruiting
NCT05706025
Study to Evaluate EnteroTracker® As a Sampling Method to Screen for Barrett's Esophagus/Esophageal CancerNo drug interventionsdiagnosticNot Availableenrolling_by_invitation
NCT00474903
Esomeprazole Magnesium With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett Esophagusprevention2completed
NCT01802203
trūFreeze® Spray Cryotherapy Patient RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT02199002
Acid Pocket: Position and AspirationNo drug interventionsbasic_scienceNot Availablecompleted
NCT05133102
Longitudinal Oral Microbiome Sampling for BENo drug interventionsNot AvailableNot Availablerecruiting
NCT05216133
Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05778851
Clinical Utility of a Non Endoscopic Device EsoCheck and Biomarker EsoGuard as Alternative to Endoscopy for Screening for Barrett's Esophagus in At Risk PopulationNo drug interventionsscreeningNot Availablerecruiting
NCT00411151
Efficacy and Safety of Sunitinib in Metastatic Gastric Cancertreatment2completed
NCT05056051
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's EsophagusNo drug interventionsdiagnosticNot Availablerecruiting
NCT03388047
Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's OesophagusNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT03961945
Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal AdenocarcinomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT02396745
TECR & ECM Placement for Esophageal High Grade DysplasiaNo drug interventionstreatmentNot Availableterminated
NCT00576498
Novel Imaging Techniques in Barrett's EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT04843397
Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT05229783
High Resolution Virtual Chromoendoscopy Versus Seattle Protocol for the Surveillance of Barrett's EsophagusNo drug interventionsdiagnosticNot Availablerecruiting
NCT02994693
Natural History of Barrett's Esophagus Using Tethered Capsule EndomicroscopyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04457193
Outcomes After Transoral Incisionless Fundoplication (TIF) Following Successful Endoscopic Ablation for Barrett's EsophagusNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04001478
Non-invasive Testing for Early oEesophageal Cancer and DysplasiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03228407
Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)No drug interventionsdiagnosticNot Availableunknown_status
NCT02521285
Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablationprevention2active_not_recruiting
NCT03167970
Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard EndoscopyNo drug interventionsNot AvailableNot Availablecompleted
NCT03417570
Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem StudyNo drug interventionsdiagnosticNot Availableterminated
NCT05965999
Lucid Registry StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05210049
Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in VeteransNo drug interventionsscreeningNot Availablerecruiting
NCT04400136
PPI Therapy Impact on GERD After Sleeve Gastrectomydiagnostic0unknown_status
NCT00955019
Novel Method of Surveillance in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT04214119
EsophaCap for the Detection of Early Esophageal CarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02988934
The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. RegistryNo drug interventionsNot AvailableNot Availableterminated
NCT03434834
OCT Pilot in EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT04151524
Classification of Adenocarcinoma of the Esophagogastric JunctionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02478996
Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for EsophagectomyNo drug interventionstreatmentNot Availableunknown_status
NCT00321958
Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal CancerNo drug interventionsNot AvailableNot Availableterminated
NCT04301986
Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's EsophagusNo drug interventionsotherNot Availablecompleted
NCT03459339
Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule EndomicroscopyNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT06008522
Safety and Feasibility of Immuno-OCTpreventionNot Availablenot_yet_recruiting
NCT02310230
An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI EndoscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT02455648
Autologous Cell Sheets Transplantation After ESD in the EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT03859557
The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps BiopsyNo drug interventionsNot AvailableNot Availablecompleted
NCT03073226
A Prospective Study Comparing the Accuracy of Olympus Lucera Spectrum Technology vs Olympus Lucera Elite Technology in the in Vivo Diagnosis of Barrett's Oesophagus and Colorectal Polyps: The ELITE StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT03097666
Evaluation of Safety and Dose Response Using C2 CryoBalloon™ Swipe Ablation System for Barrett's EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT04621474
Non-magnified NBI in Barrett's Oesophagus Neoplasia Detection and DelineationNo drug interventionsNot AvailableNot Availableunknown_status
NCT02004782
Barretts oEsophageal Resection With Steroid Therapy Trialprevention4withdrawn
NCT01447927
Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagusprevention2completed
NCT03852576
Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the EsophagusNo drug interventionsdiagnostic1terminated
NCT04818476
Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's EsophagusNo drug interventionsNot AvailableNot Availableunknown_status
NCT03375060
Histology Post-Endoscopic Eradication Therapy (EET)No drug interventionsNot AvailableNot Availablecompleted
NCT00386594
Pilot Study of Oral 852A for Elimination of High-Grade Dysplasia in Barrett's EsophagusNo drug interventionstreatmentNot Availableterminated
NCT04561791
Evaluation of Tethered Capsule Endomicroscopy as a Screening Tool for Barrett's Esophagus in the Primary Care SettingNo drug interventionsscreeningNot Availableenrolling_by_invitation
NCT03015389
Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and AdenocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04656392
Early Detection of Barrett's Esophagus in Participants With Reflux Symptoms in Primary CareNo drug interventionsdiagnosticNot Availablecompleted
NCT00576992
Demographics and Findings of Upper Endoscopy PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT05524844
The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE)No drug interventionsNot AvailableNot Availablerecruiting
NCT04392167
a/LCI-OCT Pilot in EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT03830801
Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's EsophagusNo drug interventionsdevice_feasibilityNot Availablerecruiting
NCT01097304
Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasiaprevention2completed
NCT00282672
Ablation of Intestinal Metaplasia Containing DysplasiaNo drug interventionstreatmentNot Availablecompleted
NCT01776346
Barrett's Esophagus Patient RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT05247346
Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo MeasurementsNo drug interventionsdiagnosticNot Availablerecruiting
NCT03366012
Rapid Assessment of Esophageal Adenocarcinoma Risk TestNo drug interventionsscreeningNot Availablesuspended
NCT04587310
Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01391208
Esophageal Protocol for Detection of Neoplasia in the Digestive Tractdiagnostic1completed
NCT05530343
Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing SurveillanceNo drug interventionsscreeningNot Availablerecruiting
NCT01618643
Aceto-whitening in the Assessment of Gastrointestinal NeoplasiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04867590
A Study Comparing the Effectiveness of EndoRotor Versus Radiofrequency in Treating Barrett's EsophagusNo drug interventionstreatmentNot Availablerecruiting
NCT04642690
Nitrates and IL-8 in Barrett's EsophagusNo drug interventionsNot AvailableNot Availableterminated
NCT02284802
Early Detection of Tumors of the Digestive Tract by Confocal EndomicroscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT02890979
Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux DiseaseNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT02583087
ESD for the Treatment of Early Barrett's NeoplasiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00217087
Endoscopic Therapy of Early Cancer in Barretts EsophagusNo drug interventionstreatment2completed
NCT04312633
Clinical Utility of WATS3D: A 5-Year Prospective StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06346054
Molecular Assessment for Gastro-Esophageal CancerNo drug interventionsdiagnosticNot Availablerecruiting
NCT04939051
Obeticholic Acid for Prevention in Barrett's Esophagusprevention2recruiting
NCT03311451
C2 CryoBalloon™ 180 Ablation System Dose De-escalation Study.No drug interventionstreatmentNot Availableenrolling_by_invitation
NCT02549053
Prevalence of Human Papillomavirus in Barrett Esophagus Compared With ControlsNo drug interventionsNot AvailableNot Availablecompleted
NCT05578677
Endoscopic Biopsy Techniques in Barrett's Esophagus PatientsNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT06071845
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal SamplesNo drug interventionsscreeningNot Availablerecruiting
NCT04295811
Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EACNo drug interventionsdiagnosticNot Availablerecruiting
NCT05846971
Clinical Utility of Methylation-based Prognostic Assay for Barrett's EsophagusNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT01129778
Assessment of Zegerid on Esophageal pH in Patients With Barrett's EsophagustreatmentNot Availableterminated
NCT03554356
Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)No drug interventionstreatmentNot Availablerecruiting
NCT00431756
Novel Biomarkers in the Neoplastic Progression of Barrett's EsophagusNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00848237
HALO Patient Registry: Ablation of Barrett's EsophagusNo drug interventionstreatmentNot Availablecompleted
NCT03471052
Radiofrequency Ablation vs Sham Procedure for Symptomatic Cervical Inlet PatchNo drug interventionstreatmentNot Availableunknown_status
NCT00587652
Methylene Blue Chromoendoscopy in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT04329000
On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.treatmentNot Availablecompleted
NCT05051475
Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's EsophagusNo drug interventionstreatmentNot Availableunknown_status
NCT03060642
The Microenvironment in Barrett's EsophagusNo drug interventionsNot AvailableNot Availablecompleted
NCT01209013
Safety of Photodynamic Therapy (PDT) in the Ablation of High-grade Dysplasia (HGD) in Barrett's Esophagus (BE)No drug interventionstreatment3withdrawn
NCT05107219
GCC Agonist Signal in the Small Intestineprevention1recruiting
NCT05628441
Real-time Computer Aided Detection of Barrett's NeoplasiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03670134
Predict Recurrence of Barrett's Esophagus After Complete Eradication of Intestinal MetaplasiaNo drug interventionspreventionNot Availablewithdrawn
NCT06532734
Barrett's Esophagitis in Anorexia Nervosa Binge/Purge SubtypeNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03468634
Raman Probe for In-vivo Diagnostics (During Oesophageal) EndoscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT03329534
Gluten Related Disorders in Barrett's EsophagusNo drug interventionsbasic_scienceNot Availableunknown_status
NCT02451124
Non-endoscopic Brushing of the Esophagus Using a Non-endoscopic Inflatable Balloon of the Esophagus in Screening for Barrett EsophagusNo drug interventionsscreeningNot Availablecompleted
NCT05463796
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05690958
Public's Intended Uptake and Views on Organization of Esophageal Cancer ScreeningNo drug interventionsNot AvailableNot Availablerecruiting
NCT04293458
Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BENo drug interventionsscreeningNot Availablecompleted
NCT03222635
Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal AdenocarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT00233935
Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagusprevention1completed
NCT03216135
Microbiome Involvement With Barrett's Esophagus and Progression to Esophageal AdenocarcinomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03835663
The Bacterial Composition of the Stomach in Reflux DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02514525
Multi-center Clinical Study to Evaluate the C2 CryoBalloon Focal Ablation SystemNo drug interventionstreatmentNot Availableunknown_status
NCT05200325
Clinical Utility Evidence for TissueCypher®No drug interventionsdiagnosticNot Availablecompleted
NCT03990025
Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer PrecursorsNo drug interventionsdiagnosticNot Availablecompleted
NCT05753748
Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade DysplasiaNo drug interventionstreatmentNot Availablerecruiting
NCT02729948
Tethered Capsule Endoscope in Screening Patients With Barrett EsophagusNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT03387982
Balloon Cryotherapy vs. Radiofrequency Ablation Pain StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03546660
Imaging of the Esophagus Using a SECM CapsuleNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT06030180
CLUE: CLinical Utility Study of EsoGuardNo drug interventionsdiagnosticNot Availablerecruiting
NCT03008980
WATS3D for the Detection of Esophageal DysplasiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04478929
Early Detection of Barrett's Esophagus Through Deep Image RetrievalNo drug interventionsNot AvailableNot Availableunknown_status
NCT02606292
Photoacoustic Endoscopy of Barrett's EsophagusNo drug interventionsdiagnostic0completed
NCT02407392
"Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study)diagnosticNot Availablecompleted
NCT05579444
Systems Biology of Gastrointestinal and Related DiseasesNo drug interventionsNot AvailableNot Availableterminated
NCT03205501
Molecular Fluorescence Endoscopy of (Pre)Malignant Esophageal Lesionsdiagnostic1completed
NCT03877601
Detection of Early Esophageal Cancer by NIR-FME.diagnostic2unknown_status
NCT03191604
Impact of NBI on Patients Undergoing Endoscopic Eradication TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT03853772
The Johns Hopkins Heartburn Center RegistryNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00489268
Micro-Layer Ablation of Barrett's Metaplasia- A Two-Phase, Multi-Center Trial - Extension of Follow-up to 5 YearsNo drug interventionstreatmentNot Availablecompleted
NCT03427346
Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc ResectionNo drug interventionstreatmentNot Availablerecruiting
NCT00449995
Confocal Laserscanning Microscopy for Detection of Barretts EsophagusNo drug interventionsdiagnosticNot Availablecompleted
NCT02688114
Healing of the Esophageal Mucosa After RFA of Barrett's EsophagusNo drug interventionsbasic_scienceNot Availablecompleted
NCT02560623
A Minimally-Invasive Sponge on a String Device for Screening for Barrett's EsophagusNo drug interventionsscreeningNot Availablecompleted
NCT05642338
A Multicenter Prospective Cohort Study Comparing Random Biopsies Versus Wide-Area Transepithelial Brush-Sampling (WATS) for Surveillance of Barrett's Esophagus, the WATS-EURO2 StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03589443
Study of Multiplexed Heptapeptides for Detection of Neoplasia in the EsophagusNo drug interventionsdiagnostic1completed