Depression, Bipolar (DBCOND0030402)

Identifiers

Synonyms
Bipolar, Depression / Depression Bipolar / Bipolar Depression / Bipolar I Depression / Bipolar affective disorder, depressed / Bipolar affective disorder, current episode depression (disorder) / Bipolar disorder, unspecified / Bipolar disorder / Manic depressive reaction / Bipolar affective disorder, unspecified / Manic depressive / Reaction manic-depressive / Psychosis manic-depressive / Manic depressive illness / Manic depression / Manic depressive psychosis / Bipolar affective disorder / Bipolar disorders / Bipolar disorder (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Bupropion
A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Lithium cation
A drug used for the management of bipolar disorder and other psychiatric conditions.
Lumateperone
A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia.
Lurasidone
An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02549547
Jump Step - A Participatory Approach to Physical Activity & Mental WellnessNo drug interventionstreatmentNot Availableunknown_status
NCT00245973
Study Evaluating Bifeprunox in Bipolar Depressiontreatment3completed
NCT02567110
Magnetic Resonance Spectroscopy (MRS) in Midlife DepressionNo drug interventionsNot AvailableNot Availablecompleted
NCT06462196
Natural History of Depression, Bipolar Disorder and Suicide RiskNo drug interventionsNot AvailableNot Availablerecruiting
NCT01396447
Safety, Tolerability, and Efficacy of Cariprazine in Participants With Bipolar Depressiontreatment2completed
NCT00835107
An Investigation of Sleep Architecture in Ziprasidone-Treated Bipolar Depressiontreatment4completed
NCT02778256
Study of the Effectiveness of Vestibular Stimulation Treatment in the Depressive Phase of Bipolar DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT03287037
The Effects of tDCS on Depressive Symptoms,Neurocognitive Function and HRV in Unipolar Depression and Bipolar DepressionNo drug interventionstreatmentNot Availablecompleted
NCT04399070
The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT)treatmentNot Availableunknown_status
NCT03360942
Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant DepressionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00621842
Lamotrigine for Symptoms of Geriatric Bipolar Depressiontreatment3completed
NCT00191399
Bipolar Depression Study: Bipolar Depression Assessment Study on Treatment Responsetreatment4completed
NCT04640636
IM Ketamine vs Midazolam for Suicidal ER Patientstreatment4active_not_recruiting
NCT00608296
Functional and Neurochemical Brain Changes Bipolar DepressionNo drug interventionsNot AvailableNot Availablecompleted
NCT00186186
Depakote ER in Bipolar Depressiontreatment4completed
NCT04469322
Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00483548
Adjunctive Ziprasidone in the Treatment of Bipolar I Depressiontreatment3completed
NCT05211466
Digital Care Chains in Health Care - a Study of Care Consumption, Care Quality, Work Environment and Well-beingNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04701866
Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00590265
Light-Therapy in the Treatment of the Acute Phase of the Bipolar Type II DepressionNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01303601
Efficacy of Olanzapine Monotherapy for Treatment Bipolar Ⅰ Depressiontreatment4completed
NCT00510146
Olanzapine Treatment of Patients With Bipolar I Disordertreatment3completed
NCT04846010
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2No drug interventionstreatment1 / 2unknown_status
NCT04643210
Management of my Bipolarity Intervention in Bipolar Disorder PatientsNo drug interventionssupportive_careNot Availableunknown_status
NCT00422214
Phase III/Seroquel SR Bipolar Depression Monotherapy - UStreatment3completed
NCT05568823
Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar DisorderNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02625779
Combined Cytidine and Creatine-containing Drug in the Treatment of the Bipolar Depressiontreatment2withdrawn
NCT05913947
Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)treatment4recruiting
NCT02827045
Study of a Vestibular Biomarker of Phase in Bipolar DisorderNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02152878
Transcranial Direct Current Stimulation for the Treatment of Bipolar DepressionNo drug interventionstreatment2 / 3completed
NCT04057378
Optimal Electrical Stimulus During Electroconvulsive TherapyNo drug interventionstreatment4recruiting
NCT03538275
Chronobiology and Depression: Circadian Analytics as a Biomarker for Depressive SubtypesNo drug interventionsNot AvailableNot Availablecompleted
NCT05436613
Transcranial Direct Current Stimulation Therapy for Bipolar DepressionNo drug interventionstreatmentNot Availablecompleted
NCT05767073
LIVES: Personalized Lifestyle Intervention for Patients With DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT04121091
Pramipexole to Target "Anhedonic Depression"treatment2completed
NCT06105762
Ketogenic Diet for DepressionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02919280
Dallas 2K: A Natural History Study of DepressionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03423680
A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depressiontreatment3recruiting
NCT01898429
Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD)No drug interventionstreatmentNot Availablecompleted
NCT00060489
Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients With Bipolar Depressiontreatment3completed
NCT05958940
BioClock: Bright Light Therapy for Depressive DisordersNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06599099
Deep Brain Stimulation of Treatment-Resistant Bipolar DepressionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00322764
Phase II Study to Assess RG2417 in the Treatment of Bipolar I Depressiontreatment2completed
NCT06372964
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patientstreatment3recruiting
NCT00857584
Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapytreatment3completed
NCT03918954
Comparison of Physical and Virtual Sensory Room in an Inpatient SettingNo drug interventionshealth_services_researchNot Availablecompleted
NCT04471454
Verification of the Reliability and Validity of THINC-it Tool in Bipolar DepressionNo drug interventionsNot AvailableNot Availablecompleted
NCT00908154
Safety, Tolerability and Pharmacokinetics of Repeat Doses of GSK1014802.treatment1completed
NCT06126198
rTMS Feasibility Study on Adolescent Depression StimulationNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT02839798
NeoSync TMS Treatment for Bipolar I DepressionNo drug interventionstreatment2terminated
NCT06524505
Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT06369805
EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSIONNo drug interventionsNot AvailableNot Availablecompleted
NCT00562861
Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopramtreatment2 / 3completed
NCT02800161
Trehalose as add-on Therapy in Bipolar Depressiontreatment3completed
NCT00203528
Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disordertreatment4completed
NCT00805493
Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar Disordertreatment2terminated
NCT01586793
Repetitive Transcranial Magnetic Stimulation for Treating Resistant Bipolar DepressionNo drug interventionstreatment2 / 3completed
NCT03674671
Ketamine Versus Electroconvulsive Therapy in Depressiontreatment3suspended
NCT00305578
Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depressiontreatment4completed
NCT06370988
Theta-Burst Stimulation for Bipolar DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT05249309
Naturalistic Study of Ketamine in the Treatment of DepressionNot AvailableNot Availableactive_not_recruiting
NCT05939115
Intensive Accelerated Theta Burst Stimulation in Treatment of Patients With Bipolar Depression and SuicidalityNo drug interventionstreatmentNot Availablerecruiting
NCT04285515
Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disordertreatment3completed
NCT04427137
Accelerated LFR for Bipolar Patients During the COVID-19 PandemicNo drug interventionstreatmentNot Availablecompleted
NCT00119652
Seroquel in Bipolar Depression Versus SSRItreatment3completed
NCT04059952
Mechanism of Action of Electroconvulsive TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03641300
Efficacy of Convulsive Therapies for Bipolar DepressionNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00868959
Lurasidone - A 24-week Extension Study of Patients With Bipolar I Depressiontreatment3completed
NCT05054699
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority StudyNo drug interventionstreatment2 / 3recruiting
NCT02749006
Efficacy of rTMS in Bipolar DepressionNo drug interventionstreatmentNot Availableterminated
NCT03573349
Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:treatment0active_not_recruiting
NCT00988949
Proof Of Mechanism Study To Determine Efficacy Of PF-04455242 In Blocking Spiradoline (PF-00345768) Stimulated Prolactin Releasebasic_science1completed
NCT00789113
Determination of Absorption and Elimination of Lamotrigine-XRdiagnostic1 / 2completed
NCT06022913
Behavioural Activation for Bipolar DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT03711019
Efficacy of Convulsive Therapies During ContinuationNo drug interventionstreatmentNot Availablerecruiting
NCT00893841
Bipolar Study of Seroquel XR With Pramipexole Dihydrochloridetreatment2completed
NCT00217217
Low Field Magnetic Stimulation Treatment for Bipolar DepressionNo drug interventionstreatment3terminated
NCT03279224
Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar DisorderNo drug interventionstreatment2 / 3unknown_status
NCT03658824
Behavioural Activation for Bipolar Depression: A Case SeriesNo drug interventionstreatmentNot Availablecompleted
NCT00657735
Double Blind Randomized Controlled, H1 Coil In Subjects With Bipolar DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT05973786
The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.treatment3recruiting
NCT01543139
Cytidine- and Creatine-Containing Drug in Treating Bipolar Depressiontreatment2withdrawn
NCT05393648
Bipolar Efficacy Biomarkers for rTMSNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00844857
A Study for Assessing Treatment of Patients Ages 10-17 With Bipolar Depressiontreatment4completed
NCT01880957
PET and MRI Brain Imaging of Bipolar Disorderbasic_scienceNot Availablecompleted
NCT04664257
Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive SymptomsNo drug interventionstreatmentNot Availablerecruiting
NCT01639482
Neuroimaging Studies of the Treatment of Bipolar Depression With CitalopramNo drug interventionsNot AvailableNot Availablecompleted
NCT05683431
Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)No drug interventionstreatmentNot Availablecompleted
NCT04998773
Efficacy and Biomarkers of Response of TBS in Treatment Resistant DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT06488573
The Effect of a Nutritional Intervention Focused on Dietary Pattern in the Cardiovascular Risks of Individuals With Bipolar DisorderNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00720473
Lamotrigine Therapy in Geriatric Bipolar Depressionbasic_scienceNot Availablecompleted
NCT02989727
Melancholic Symptoms in Bipolar Depression and Responsiveness to Lamotriginetreatment4completed
NCT02600494
Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depressiontreatment3completed
NCT03484494
Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar DepressionNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT02239094
Biosignatures of Latuda for Bipolar DepressiontreatmentNot Availablecompleted
NCT01403662
Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depressiontreatment3completed
NCT03679962
Triple Chronotherapy in AdolescentsNo drug interventionstreatmentNot Availablecompleted
NCT02088580
Feasibility and Tolerability of Adjunct Chronotherapy in Depressed InpatientsNo drug interventionstreatmentNot Availablecompleted
NCT00914680
Berlin Magnetic Seizure Therapy Depression Trial 01No drug interventionstreatment3completed
NCT01390389
Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depressionbasic_scienceNot Availablecompleted
NCT06369792
PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSIONNo drug interventionsNot AvailableNot Availablerecruiting
NCT01919892
Longitudinal Study on the Neuroprotective and Neurotrophic Effects of Lithiumtreatment4completed
NCT03396744
Bright Light Therapy in the Treatment of Non-seasonal Bipolar DepressionNo drug interventionstreatment1 / 2unknown_status
NCT01768767
Trial of Ketamine and Lithium Therapy in Bipolar Depressiontreatment2withdrawn
NCT01986101
A Phase III Study of SM-13496 in Patients With Bipolar I Depression.treatment3completed
NCT04210804
A Prophylactic Trial of Omega-3 Polyunsaturated Fatty Acids in Bipolar DisorderNo drug interventionstreatment2completed
NCT05603104
Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failuretreatment3recruiting
NCT02155972
The Safety and Effectiveness of Probiotic Supplementation on Bipolar DepressionNo drug interventionstreatment2terminated
NCT00762268
A Trial of SAMe for Treatment-Resistant Bipolar DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00720369
CoQ10 in Geriatric Bipolar Depressionbasic_scienceNot Availablecompleted
NCT06063369
PEA vs. Placebo for Major Depressiondiagnostic2recruiting
NCT03748446
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disordertreatment0recruiting
NCT02362412
Study to Evaluate the Effects of Switching Different Strength Forms of FK949E in Bipolar Disorder Patients With Major Depressive Episodestreatment3completed
NCT02974010
Sequential Therapy for the Treatment of Severe Bipolar Depression.treatment2completed
NCT01309581
Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in DepressiontreatmentNot Availableterminated
NCT01929681
Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00566150
Levetiracetam in the Management of Bipolar DepressiontreatmentNot Availablecompleted
NCT01962350
Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety EvaluationNo drug interventionstreatmentNot Availablecompleted
NCT02640950
An Open Label Trial of TMS Therapy for Bipolar DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00817323
What is the Antidepressant Mechanism of Action of Quetiapine in Bipolar Depression?No drug interventionsdiagnostic3withdrawn
NCT00444938
Evaluation of the H-Coil Transcranial Magnetic Stimulation (TMS) Device in the Treatment of Bipolar DepressionNo drug interventionstreatment1completed
NCT02593643
Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression.treatment0completed
NCT05228964
Focused Ultrasound Amygdala NeuromodulationNo drug interventionstreatment2active_not_recruiting
NCT01213121
Neurophysiologic Changes in Patients With Bipolar Depressionbasic_science4unknown_status
NCT00852202
Safety and Efficacy of RGH-188 (Cariprazine) in Bipolar Depressiontreatment2completed
NCT01562184
Investigating tDCS as a Treatment for Unipolar and Bipolar DepressionNo drug interventionstreatment2 / 3completed
NCT04133233
Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disordertreatment2completed
NCT00457054
Functional Connectivity in Mood Regulating Circuit In Bipolar Depression and Maniaprevention4completed
NCT01256177
Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depressiontreatment3completed
NCT06229977
A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depressiontreatment2recruiting
NCT00198198
Aripiprazole Treatment of Bipolar Depressiontreatment4completed
NCT05384405
aiTBS for Relieving NSSI in Depressive PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT00578383
Low Field Magnetic Stimulation in Mood Disorders Using the LFMS DeviceNo drug interventionstreatmentNot Availablecompleted
NCT03603561
Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT03349528
Probiotics to Prevent Relapse After Hospitalization for Bipolar Depressiontreatment2enrolling_by_invitation
NCT00757328
Treatment Clinical Practice in Bipolar Depression in SpainNo drug interventionsNot AvailableNot Availablecompleted
NCT00566111
Ceftriaxone in the Management of Bipolar DepressiontreatmentNot Availableterminated
NCT04420793
Voice Changes During ECTNo drug interventionsNot AvailableNot Availablecompleted
NCT01914393
Pediatric Open-Label Extension Studytreatment3completed
NCT03310593
Cannabidiol as an Adjunctive Treatment for Bipolar Depressiontreatment2 / 3terminated
NCT00926393
Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar DepressionNot Available4completed
NCT03965871
Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depressiontreatment2completed
NCT02600507
Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depressiontreatment3completed
NCT05296356
OSU6162 in Bipolar Depression (OBID)treatment2recruiting
NCT00369915
The Antidepressant Efficacy of the Anticholinergic Scopolaminetreatment2terminated
NCT05465915
Pulse Width 0.15ms vs 0.30ms in Electroconvulsive TherapyNo drug interventionstreatment0unknown_status
NCT00363337
A Preliminary Study of the Effectiveness and Tolerability of Aripiprazole in Bipolar Depressiontreatment4completed
NCT06417437
Non-invasive BCI and Application Verification for Depressed PeopleNo drug interventionstreatment4recruiting
NCT00384332
Medication, Weight Gain and GI Hormonestreatment4completed
NCT06088732
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depressionbasic_science1 / 2recruiting
NCT00868452
Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Add-on)treatment3completed
NCT03402152
NRX101 Glx Biomarker Validation Studytreatment2 / 3completed
NCT00055575
Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studiestreatment2terminated
NCT00490542
Safety Study of Ziprasidone (Geodon) for the Depressive Mixed Statetreatment2completed
NCT00868699
Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Monotherapy)treatment3completed
NCT00719706
The Use of a Mitochondrial Enhancement Treatment in Bipolar Disordertreatment2completed
NCT05060549
Dopamine D3 Receptor Occupancy in Bipolar Depressionbasic_science4not_yet_recruiting
NCT04939649
Ketamine as an Adjunctive Therapy for Major Depression (2)treatment3active_not_recruiting
NCT04417049
Treatment of Bipolar Depression With Pentoxifyllinetreatment0completed
NCT03902613
18F-DOPA PET to Elucidate the Antidepressant Mechanism of Lurasidone in Bipolar Disorderbasic_science4completed
NCT05357313
Adjunctive Bright Light Therapy in Patients With Bipolar Depression and EveningnessNo drug interventionstreatmentNot Availablerecruiting
NCT04480918
University of Iowa Interventional Psychiatry Service Patient RegistryNot AvailableNot Availablerecruiting
NCT03336918
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar DisorderNot AvailableNot Availablerecruiting
NCT06506019
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depressiontreatment1not_yet_recruiting
NCT01807741
Asenapine for Bipolar Depressiontreatment2terminated
NCT00206141
Seroquel in Bipolar Depression Versus Lithiumtreatment3completed
NCT01284517
Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depressiontreatment3completed
NCT02176824
Chronotherapy Randomized Controlled TrialNo drug interventionstreatmentNot Availableterminated
NCT05004896
Ketamine for Treatment-Resistant Bipolar Disordertreatment2recruiting
NCT01042496
Bipolar Depression Before and After Lamotrigine Treatmenttreatment3completed
NCT03339596
Effects of Erythropoietin for Cognitive Side-effects of ECTtreatment2completed
NCT00566735
The Use of Galantamine HBr (Reminyl) in Electroconvulsive Therapy: Impact on Mood and Cognitive Functioningtreatment3completed
NCT01093963
Efficacy Study of Lisdexamfetamine to Treat Bipolar Depressiontreatment3terminated
NCT04226963
A Naturalistic Study of Ketamine for Treatment Resistant Mood DisordersNot AvailableNot Availablecompleted
NCT01881763
Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depressiontreatment4completed
NCT02703363
Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depressiontreatment3completed
NCT05705063
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar IllnessNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04235686
8 Week Multi-site Study of MYDAYIS® for Bipolar Depressiontreatment2recruiting
NCT05340686
Braining- Aerobic Physical Activity as Add on Treatment in Bipolar DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT03468686
The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive DisorderNo drug interventionstreatmentNot Availablecompleted
NCT00470639
Transcranial Magnetic Stimulation for Bipolar DepressionNo drug interventionstreatment1 / 2withdrawn
NCT01514422
Minocycline for Bipolar Depressiontreatment4completed
NCT00272025
Treatment Resistant Bipolar Depressiontreatment1terminated
NCT00359125
RU-486 in the Treatment of Bipolar Depressiontreatment2withdrawn
NCT04569448
Brexpiprazole Treatment for Bipolar I Depressiontreatment3recruiting
NCT06560957
SYNCED - SYNChronized Eating in Bipolar Depression StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05481957
Vortioxetine Adjunctive Treatment in Bipolar Depressiontreatment4completed
NCT05228457
Intensive TMS for Bipolar DepressionNo drug interventionsotherNot Availablecompleted
NCT01587066
Efficacy of Quetiapine XR Versus Divalproex on Clinical Outcome Quality of Sleep and Quality of Life in Bipolar Depressiontreatment4withdrawn
NCT00217165
Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Studytreatment2completed
NCT05339074
Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depressiontreatment2recruiting
NCT00835120
Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin Resistancetreatment4completed
NCT01255982
Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-upNo drug interventionsNot AvailableNot Availablecompleted
NCT00811473
Pediatric Bipolar Depressiontreatment3completed
NCT03249376
Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted Globallytreatment3completed
NCT06516991
Task-State-Based Temporal Interference Stimulation (TI) to Improve Depression in Patients With Bipolar DisorderNo drug interventionstreatmentNot Availablerecruiting
NCT01566591
Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT00535262
A Pilot Study Assessing EmSam in Bipolar Depressiontreatment4terminated
NCT03256162
Ketamine as an Adjunctive Therapy for Major Depressionother1completed
NCT01479829
Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depressiontreatment4completed
NCT02719392
A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depressiontreatment4suspended
NCT01557192
Low Field Magnetic Stimulation (LFMS) in Mood Disorders: 6 TreatmentsNo drug interventionstreatment1suspended
NCT03395392
NRX-101 for Bipolar Depression With Subacute Suicidal Ideationtreatment2 / 3completed
NCT03427892
Brexpiprazole for Bipolar Depressiontreatment4completed
NCT00544544
Riluzole in the Treatment of Bipolar DepressiontreatmentNot Availablecompleted
NCT01884844
Vitamin D Supplementation for Bipolar DepressiontreatmentNot Availablecompleted
NCT02740244
Effect of Intermittent ThetaBurst Stimulation in Treatment-resistant Bipolar DepressionNo drug interventionsotherNot Availableterminated
NCT01805440
Uridine Adolescent Bipolar Depression Randomized Controlled TrialotherNot Availablecompleted
NCT01051440
Magnetic Resonance Imaging Study of Lisdexamfetamine for Bipolar Depressiontreatment4terminated
NCT05779267
NRX-101 Expanded AccessNo drug interventionsNot AvailableNot Availableavailable
NCT00203567
Carbamazepine Extended-Release for the Treatment of Bipolar Depressiontreatment4completed
NCT00938301
A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult VolunteersNo drug interventionstreatment1completed
NCT03396601
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depressiontreatment3active_not_recruiting
NCT00523601
Quetiapine Efficacy in Bipolar Depression StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03396068
NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideationtreatment3active_not_recruiting
NCT00224510
A Study To Investigate The Antidepressant Effect Of Lamotrigine In Patients With Bipolar Disorder Using Lithiumtreatment3completed
NCT03567681
Comparison of Two Forms of Oxcarbazepine for the Treatment of Bipolar Depressiontreatment4unknown_status
NCT02048995
Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative BiomarkerNo drug interventionsNot AvailableNot Availablecompleted
NCT05375214
iTBS in Bipolar I DepressionNo drug interventionstreatmentNot Availablecompleted
NCT02363738
12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depressiontreatment2completed
NCT00812058
A Study to Assess the Safety, Tolerability and Efficacy of RG2417 in Bipolar I Depressiontreatment2completed
NCT04383691
A Study of Lurasidone Compared With Placebo for the Treatment of Bipolar I Depressiontreatment3terminated
NCT02046369
Lurasidone Pediatric Bipolar Studytreatment3completed
NCT00481195
Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disordertreatment2completed