Oral Lichen Planus (DBCOND0030626)

Identifiers

Synonyms
Lichen Planus, Oral / Oral lichen planus / Oral lichen planus (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Tacrolimus
A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04289233
Molecular & Cellular Characterisation of Oral Lichen PlanusNo drug interventionsNot AvailableNot Availablecompleted
NCT06533033
Melatonin Epigenetic Potential in Preventing Malignant Transformation of Oral Lichen PlanuspreventionNot Availableactive_not_recruiting
NCT06550154
Association Between Oral Lichen Planus and Thyroid DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01061853
Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichentreatment3terminated
NCT04523077
Association of Oral Lichen Planus and Thyroid DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04091698
Clinical and Biochemical Assessment of the Effect of Topical Use of Coenzyme Q10 Versus Topical Corticosteroid in Management of Symptomatic Oral Lichen Planus: Randomized Controlled Clinical Trialtreatment1unknown_status
NCT06135805
Impact of Fluocinonide 0,05% in Oral Lichen PlanustreatmentNot Availablerecruiting
NCT05127083
Oral Lichen Planus TreatmentNo drug interventionstreatmentNot Availablecompleted
NCT03257228
The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2)No drug interventionsNot AvailableNot Availablecompleted
NCT02443311
Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planustreatment4completed
NCT02154607
Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive Oral Lichen Planus in PatientsNo drug interventionspreventionNot Availablecompleted
NCT03836885
Apremilast - Oral Lichen Planus Trialtreatment2withdrawn
NCT00297037
Pimecrolimus Cream for Oral Lichen Planustreatment2completed
NCT02329600
Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planustreatment3completed
NCT03592342
Intra-oral Treatment of OLP With Rivelin®-CLO Patchestreatment2completed
NCT04278599
Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patientstreatment4unknown_status
NCT04293718
Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival BiopsyNo drug interventionsNot AvailableNot Availablecompleted
NCT02587117
A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planustreatment4completed
NCT02920658
Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseasestreatment2completed
NCT03975322
Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based ImmunoscoreNo drug interventionsNot AvailableNot Availablerecruiting
NCT06449248
Oral Lichen Planus and Systemical Oncological ComorbiditiesNo drug interventionsNot AvailableNot Availablecompleted
NCT04193748
Evaluation of Topical Pomegranate Extracts in Management of Oral Lichen Planus (A Randomized Clinical Trial)treatment4completed
NCT04153266
Oral Epithelial Dysplasia Informational Needs QuestionnaireNo drug interventionsNot AvailableNot Availablecompleted
NCT04126720
Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symptomatic Oral Lichen Planus Patients: Randomized-controlled Clinical TrialNo drug interventionstreatment1completed
NCT01083420
The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planustreatment3unknown_status
NCT05997173
The Regulatory Role of Immune Response in Oral Lichen PlanusNo drug interventionsNot AvailableNot Availablerecruiting
NCT05942794
Identification of Oral Lesions Through an Autofluorescence SystemNo drug interventionsscreeningNot Availablerecruiting
NCT04079491
Intra and Extra Oral Inspection of Oral MucosaNo drug interventionsNot AvailableNot Availableterminated
NCT06233591
Evaluating LP-10 in Subjects With OLPtreatment2recruiting
NCT06498180
Periodontal Initial Treatment Combined With Glucocorticoid Therapy for Erosive Oral Lichen PlanusNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04765267
Micronutrients in Management of Symptomatic Oral Lichen PlanusNo drug interventionstreatmentNot Availablecompleted
NCT06060301
Topical Sulfasalazine and Oral Lichen Planustreatment3active_not_recruiting
NCT05401201
Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLPNo drug interventionssupportive_careNot Availablerecruiting
NCT00111072
Dexamethasone to Treat Oral Lichen Planustreatment2completed
NCT02106468
The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planustreatment2completed
NCT06042010
Oral Zinc Supplement as Adjunctive Therapy for Erosive Oral Lichen PlanustreatmentNot Availablecompleted
NCT06325514
Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image AnalysisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04364555
Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus.treatment2 / 3recruiting
NCT00484250
Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Othertreatment2completed
NCT03386643
Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planustreatment2completed
NCT02453503
Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planustreatment2completed
NCT04785703
Prolactin Hormone in Oral Lichen PlanusNo drug interventionsNot AvailableNot Availablecompleted
NCT06321003
SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01743690
The Use of Probiotics in Patients With Symptomatic Oral Lichen PlanuspreventionNot Availablecompleted
NCT00525421
A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planustreatment2completed
NCT03052179
The Clinical and Biological Effects Of The Use Of Probiotic VSL#3 In Patients With Oral Lichen PlanusNo drug interventionssupportive_careNot Availablecompleted
NCT03237533
Treatment Modalities of Oral Lichen Planustreatment0unknown_status
NCT04540133
Dexamethasone Solution and Dexamethasone in Mucolox™treatment2completed
NCT00737854
Free Soft Tissue Graft in Treatment of Oral Lichen PlanusNo drug interventionstreatment1unknown_status
NCT06033105
Vitamin D Deficiency as a Risk Factor for the Development and Malignant Transformation of Oral Lichen PlanusNo drug interventionsNot AvailableNot Availablecompleted
NCT02858297
Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planustreatment4completed
NCT05973097
Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT03026361
Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral CavityNo drug interventionsNot AvailableNot Availablecompleted
NCT03026478
Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planustreatment2unknown_status
NCT02744378
Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planustreatment2completed
NCT04336488
Matrix Metalloproteinases Neutralizing Agents in Oral Lichen Planustreatment0unknown_status
NCT06135259
Topical Erythropoietin Hydrogel in Management of Oral Lichen Planustreatment3not_yet_recruiting
NCT03572959
Management of Pain in Oral Lichen Planussupportive_care4completed
NCT03509675
Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.treatment2 / 3completed
NCT02421770
Chamaemelum Nobile 2% Versus Placebo Topic Gel to Treat Oral Lichen PlanusNo drug interventionstreatment3completed
NCT01544842
Tacrolimus Ointment in Oral Lichen PlanustreatmentNot Availableterminated
NCT03031899
Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection EfficacyNo drug interventionsNot AvailableNot Availablecompleted
NCT06158113
Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Studytreatment2recruiting
NCT05818618
Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen PlanustreatmentNot Availablecompleted
NCT04267419
Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT04732741
Diagnostic Accuracy of Salivary Gamma-synuclein in Oral Malignant and Premalignant LesionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03793634
Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planustreatment1unknown_status
NCT05403216
Relationship Between Oral Lichen Planus and Autoimmune Thyroid DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06204796
The Role of Vitamin D in Amelioration of Oral Lichen Planus and Its Effect on Salivary IFN-γ Leveltreatment4completed
NCT02332486
Based on Metabonomics Dryness Pathogen Type of OLP: a Dynamic StudyNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06428630
Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planustreatment0not_yet_recruiting
NCT05400057
the Oncogenic Potential of Salivary miRNA-93 and miRNA-412-3P in Oral Lichen Planus PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06332365
Evaluating Treatment Efficacy in Oral Lichen Planus: The Role of Salivary BiomarkerstreatmentNot Availablecompleted
NCT03415165
Efficacy of Green Tea Buccal Tablets in Oral Lichen Planustreatment0unknown_status
NCT00226174
A Randomized, Placebo-controlled, Double-blind Clinical Trial of Curcuminoids in Oral Lichen PlanusNo drug interventionstreatment2terminated
NCT02834520
Expression of miRNa-138 and Cyclin D1 in Oral Mucosa of Patients With Oral Lichen PlanusNo drug interventionsNot AvailableNot Availablecompleted
NCT03738176
The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker [MDA]treatment0unknown_status
NCT03682562
Diagnostic Accuracy of Salivary DNA Integrity Index in Oral Malignant and Premalignant LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01524744
A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planustreatment2unknown_status
NCT05139667
Evaluation of Mucoadhesive Tacrolimus Patch on Caspase-3 Inducing Apoptosis in Oral Lichen Planustreatment4completed
NCT06260904
Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planustreatment4not_yet_recruiting
NCT06119672
Efficacy of Probiotic Capsules With Topical Clobetasol Propionate in OLP Treatmenttreatment3recruiting
NCT04991012
Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type in the Oral Mucosa and Its Diagnostics With the Use of Autofluorescence, in Various Wavelength Ranges, in Combination With the Use of Texture Analysis and Fractal Dimensiontreatment2completed
NCT03871114
Evaluation of Salivary Level of miR-155 and IL-10 in Oral Lichen Planus Patients Before and After Treatment With Topical CorticosteroidNot AvailableNot Availablecompleted
NCT05730855
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05882864
Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysistreatment4not_yet_recruiting
NCT06078579
Salivary and Serum Leptin Levels in Oral Lichen Planus Patients: A Case-control Study.No drug interventionsNot AvailableNot Availablerecruiting
NCT03877679
The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patientstreatment1unknown_status
NCT00133107
Safety and Effectiveness of Efalizumab to Treat Oral Lichen PlanustreatmentNot Availablecompleted
NCT02276573
Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen PlanusNo drug interventionsbasic_scienceNot Availablecompleted
NCT04976673
Comparison of Clinical Efficiency of Photodynamic Therapy and Topical Corticosteroid in Treatment of Oral Lichen Planustreatment2completed
NCT00746772
Efficacy of Purslane in Treatment of Oral Lichen Planustreatment2completed
NCT05330572
Clinical and Molecular Correlates of Response to First Line Treatment in Lichen PlanusNo drug interventionsNot AvailableNot Availablerecruiting
NCT00130572
Efficacy of Elidel Cream on Erosive Oral Lichen Planustreatment3completed
NCT00656214
Treatmant of Oral Lichen Planus With Lycopenetreatment2completed
NCT06362005
The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planustreatment4not_yet_recruiting
NCT04718311
Study on Treatment for Patients With Symptomatic Oral Lichen PlanustreatmentNot Availablecompleted
NCT03687437
Lichen Planus and Mean Platelet VolumNo drug interventionsNot AvailableNot Availablecompleted
NCT04673916
Treatment Protocols for Patients With Symptomatic Oral Lichen PlanusNo drug interventionstreatmentNot Availablecompleted
NCT00102557
Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planustreatment2completed
NCT03320460
Photobiomodulation in Oral Lichen PlanustreatmentNot Availableunknown_status