NCT06332755
Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors No drug interventions treatment 1 recruiting NCT06084481
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 No drug interventions treatment 1 recruiting NCT06607406
Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery No drug interventions treatment Not Available not_yet_recruiting NCT04799054
A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors treatment 1 / 2 recruiting NCT05068102
A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab treatment 1 recruiting NCT02025062
Comprehensive Geriatric Assessment and Head and Neck Elderly Cancer Patients No drug interventions treatment Not Available completed NCT05552807
SCT200 in Combination With SCT-I10A/Paclitaxel/Docetaxel in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma treatment 1 unknown_status NCT04361409
Rituximab Plus Chemotherapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma treatment 1 completed NCT05039606
Clinical Study of Radiotherapy Combined With Nedaplatin Contrast and Cisplatin for the Treatment of Locally Advanced Head and Neck Squamous Carcinoma treatment 2 not_yet_recruiting NCT06306846
Neoadjuvant SBRT in Localized Advanced HNSCC treatment 2 recruiting NCT00634595
Trial of E10A in Head and Neck Cancer treatment 2 unknown_status NCT04428151
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009) treatment 2 active_not_recruiting NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients with EGFR-driven Advanced Solid Tumors treatment 1 recruiting NCT04913337
Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies treatment 1 / 2 active_not_recruiting NCT05674526
A Phase 1b Study of WU-NK-101 in Combination With Cetuximab treatment 1 recruiting NCT04665843
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck treatment 2 active_not_recruiting NCT04895709
A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors treatment 1 / 2 recruiting NCT06606028
Tumor-Informed ctDNA Testing of Head & Neck Intent Treatment of Squamous Cell Carcinoma No drug interventions Not Available Not Available not_yet_recruiting NCT05271604
A Phase 2 Open Label Study of BA3021 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 2 recruiting NCT05620134
Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer treatment 1 / 2 recruiting NCT06137378
European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] treatment 2 recruiting NCT06492460
2 Courses of Concurrent Cisplatin Chemoradiotherapy After Surgery for High-risk Head and Neck Squamous Cell Carcinoma treatment 3 not_yet_recruiting NCT06549816
A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors treatment 1 recruiting NCT06557889
Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas treatment 2 not_yet_recruiting NCT05802290
NIVolumab in Subjects With Recurrent or Metastatic Platinum-refrACTORy SCCHN treatment 3 completed NCT04601402
GEN-001 (Live Biotherapeutic Product) and Avelumab Combination Study for Patients With Solid Tumors Who Have Progressed on Anti-PD-(L)1 Therapy treatment 1 completed NCT04260802
A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers treatment 1 / 2 recruiting NCT01598077
A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer treatment 1 completed NCT05673577
Camrelizumab in Combination With Cetuximab and Chemotherapy for Relapsed/Metastatic HNSCC Patients treatment 2 recruiting NCT04428047
Evaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma treatment 2 terminated NCT05792228
A Standardized Intervention to Improve the Management of Chemotherapy-induced Nausea and Vomiting No drug interventions supportive_care Not Available completed NCT02479178
A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical Cancer and Squamous Cell Carcinoma of the Head and Neck treatment 2 terminated NCT04633278
CMP-001 in Combination With Pembrolizumab in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT04502888
Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or Skin No drug interventions treatment 1 terminated NCT04262388
A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation treatment 2 withdrawn NCT05845307
Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck treatment 0 not_yet_recruiting NCT05323656
A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN) treatment 2 active_not_recruiting NCT04580485
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors treatment 1 completed NCT05459415
Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC No drug interventions treatment Not Available active_not_recruiting NCT03440437
A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies treatment 1 / 2 terminated NCT06242470
A Study of MGC026 in Participants With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT05743270
Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN treatment 2 withdrawn NCT05007106
MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) treatment 2 active_not_recruiting NCT05234606
A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors treatment 1 / 2 withdrawn NCT04879849
A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers treatment 1 completed NCT04086849
Analysis of Patterns of Recurrence in Head and Neck Cancer Using Clinicopathomic Markers No drug interventions Not Available Not Available completed NCT04795713
Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1 No drug interventions treatment 1 recruiting NCT01333696
Pemetrexed as Salvage Treatment in Squamous Cell Carcinoma of Head and Neck treatment 2 unknown_status NCT03589339
NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy treatment 1 recruiting NCT01353625
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies. treatment 1 completed NCT06046625
Needs and Preferences of Patients With Head-neck Cutaneous SCC No drug interventions Not Available Not Available active_not_recruiting NCT05121948
A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) No drug interventions treatment 1 terminated NCT05182866
ASP-1929 Photoimmunotherapy (PIT) Study in Patients With Recurrent Head/Neck Cancer treatment 2 active_not_recruiting NCT04941365
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy No drug interventions diagnostic Not Available withdrawn NCT04188665
Using MASL to Combat Oral Cancer No drug interventions treatment 0 recruiting NCT04129320
Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck treatment 2 / 3 withdrawn NCT04403620
HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer No drug interventions treatment 1 / 2 recruiting NCT06046482
Phase II Trial of Magrolimab and Cetuximab with Pembrolizumab or Docetaxel for Recurrent/metastatic Head Neck Squamous Cell Carcinoma treatment 2 terminated NCT05653882
A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors treatment 1 recruiting NCT02061631
Study to Evaluate the Response Rate to Therapy With Docetaxel and Cisplatin in Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck treatment 2 completed NCT06034860
Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types treatment 1 recruiting NCT05086692
A Beta-only IL-2 ImmunoTherapY Study treatment 1 / 2 recruiting NCT00756444
A Randomized Phase 2 Pharmacokinetic Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT04091867
sEphB4-HSA With RT+Chemo or Cetux in Patients With Intermediate to High Risk LAHNSCC treatment 1 completed NCT03829501
Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer treatment 1 / 2 active_not_recruiting NCT05027204
A Study of Docetaxel for Injection (Albumin-bound) in Combination With Nivolumab in Patients With Head and Neck (SCCHN) treatment 1 / 2 unknown_status NCT00139269
Study of Docetaxel in Combination With Cisplatin and 5-Fluorouracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck treatment 1 / 2 completed NCT05935995
Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination No drug interventions other Not Available recruiting NCT06110195
Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer treatment 1 active_not_recruiting NCT05280314
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors treatment 2 recruiting NCT04780750
Concurent Chemoradiotherapy in Head and Neck Cancers treatment 3 unknown_status NCT02537223
Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck Cancer treatment 1 completed NCT00824343
A Phase II Clinical Trial to Study the Efficacy and Safety of a New Drug P276-00 in Treatment of Recurrent and/or Locally Advanced Head and Neck Cancer No drug interventions treatment 2 completed NCT00459043
Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and Neck treatment 2 completed NCT06487403
A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers No drug interventions treatment Not Available not_yet_recruiting NCT06515990
A Study of DM005 in Patients With Advanced Solid Tumors No drug interventions treatment 1 not_yet_recruiting NCT04465487
Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies treatment 1 recruiting NCT04650633
SHR-1701 in Patients With Recurrent/Metastatic Scchn treatment 2 unknown_status NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy treatment 1 terminated NCT00899054
Safety and Efficacy Study of P276-00 in Combination With Radiation in Subjects With Advanced Head and Neck Cancer No drug interventions treatment 1 / 2 completed NCT04747054
Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers treatment 3 recruiting NCT00492947
Dendritic Cell Vaccine for Head and Neck Cancer No drug interventions treatment 1 withdrawn NCT04688528
Dose De-escalation and Sentinel LN Mapping Driven Radiotherapy of Contralateral Neck in Ipsilateral Node Positive HNSCC No drug interventions treatment Not Available recruiting NCT04489888
A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10) treatment 4 completed NCT05816785
Pilot Study of Imatinib Cetuximab Combo for H & N Cancer treatment 0 recruiting NCT05621837
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy No drug interventions Not Available Not Available unknown_status NCT05053737
Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC treatment 1 suspended NCT04389632
A Study of SGN-B6A in Advanced Solid Tumors treatment 1 recruiting NCT05317000
5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC treatment 0 recruiting NCT04892875
A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers treatment 1 withdrawn NCT04266470
Monitoring Blood Flow and Metabolic Activity in Malignant Tissue of Head and Neck Region No drug interventions device_feasibility Not Available withdrawn NCT04474470
A Study to Evaluate NT219 Alone and in Combination With ERBITUX® (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer treatment 1 / 2 active_not_recruiting NCT05099549
Safety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing Cancers No drug interventions treatment 1 / 2 terminated NCT03829436
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers treatment 1 completed NCT05683418
A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With Select Solid Tumors No drug interventions treatment 1 recruiting NCT05311618
Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors treatment 1 active_not_recruiting NCT03576417
A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck treatment 3 active_not_recruiting NCT05952934
Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence treatment 2 recruiting NCT06380816
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer No drug interventions treatment 1 / 2 recruiting NCT04348916
Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors treatment 1 terminated NCT03729596
MGC018 With or Without MGA012 in Advanced Solid Tumors treatment 1 / 2 terminated NCT02715596
Changes in Body Composition After EPA Supplementation in Head and Neck Patients No drug interventions supportive_care 3 completed NCT05668858
Clinical Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma No drug interventions treatment 1 / 2 recruiting NCT04098458
Navigation for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC No drug interventions health_services_research Not Available completed NCT04117139
The Diagnostic Value of PET/MRI in Head and Neck Cancer No drug interventions diagnostic Not Available unknown_status NCT05605522
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours No drug interventions treatment 1 recruiting NCT06236425
TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC treatment 1 recruiting NCT04266730
Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab treatment 1 not_yet_recruiting NCT04030130
Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC No drug interventions health_services_research Not Available active_not_recruiting NCT06367257
App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy No drug interventions supportive_care Not Available recruiting NCT06022757
Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19) treatment 1 / 2 recruiting NCT05366166
Pembrolizumab Plus Olaparib in LA-HNSCC treatment 2 recruiting NCT04305366
MicroRNA Markers in Head and Neck Cancers No drug interventions Not Available Not Available active_not_recruiting NCT00371566
A Study Of Lapatinib Versus Placebo Followed By Chemoradiation In Patients With Locally Advanced Head And Neck Cancer treatment 2 completed NCT04183166
A Clinical Trial Evaluating TG4050 in Head and Neck Cancer No drug interventions treatment 1 / 2 recruiting NCT05215574
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT04528420
Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer No drug interventions supportive_care Not Available not_yet_recruiting NCT05578820
Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid treatment 1 completed NCT05061420
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With HNSCC (Master Protocol) (Pegathor Head and Neck 204) treatment 2 active_not_recruiting NCT06081582
Toripalimab in Combined With Cetuximab，Chemotherapy for Conversion Therapy of Locally Nonresectable OCSCC treatment 2 recruiting NCT05462873
A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT04825873
A Study to Assess Safety of Nivolumab in Routine Oncology Practice in China No drug interventions Not Available Not Available completed NCT04766827
Albumin-bound Paclitaxel Combined With Cisplatin Versus Docetaxel Combined With Cisplatin Induced Chemotherapy in Advanced Head and Neck Squamous Tummor treatment 4 unknown_status NCT06534762
Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study treatment 2 recruiting NCT04939480
Window of Opportunity Study of Preoperative Immunotherapy With Atezolizumab in Local SCCHN treatment 2 completed NCT05482880
Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region No drug interventions Not Available Not Available recruiting NCT05544929
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers treatment 1 recruiting NCT04801472
Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM) No drug interventions other Not Available unknown_status NCT03997968
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors treatment 1 / 2 active_not_recruiting NCT03219268
A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms treatment 1 completed NCT04922112
Sleep Apnea in Head and Neck Cancer Patients at the University of Colorado No drug interventions diagnostic Not Available withdrawn NCT06085781
HN-BIO: A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers No drug interventions treatment Not Available recruiting NCT04344795
Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors treatment 1 active_not_recruiting NCT04832555
Non Elective Vulnerable Elderly Radiotherapy No drug interventions treatment Not Available recruiting NCT06125223
PABLIXIMAB as Neoadjuvant Therapy for Head and Neck Squamous-cell Carcinoma No drug interventions Not Available Not Available not_yet_recruiting NCT04083599
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors treatment 1 / 2 recruiting NCT05249426
A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer treatment 1 active_not_recruiting NCT02684253
Screening Trial of Nivolumab With Image Guided, Stereotactic Body Radiotherapy (SBRT) Versus Nivolumab Alone in Patients With Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 2 completed NCT06102447
Efficacy and Safety of Netupitant and Palonosetron Hydrochloride Capsules in Preventing Nausea and Vomiting Induced by Radiochemotherapy in Head and Neck Squamous Cell Carcinoma treatment Not Available not_yet_recruiting NCT03268993
Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer No drug interventions basic_science Not Available completed NCT04215978
Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors treatment 1 active_not_recruiting NCT04603248
A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma other Not Available unknown_status NCT04220866
Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002) treatment 2 completed NCT06295731
INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC treatment 2 / 3 recruiting NCT02211027
Biological Vaccine: Semi-allogeneic Human Fibroblasts (MRC-5) Transfected With DNA No drug interventions treatment 1 withdrawn NCT04080804
Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer treatment 2 recruiting NCT06530914
A Phase II Study of MRG003 Injection Combined With Pucotenlimab Injection ± Cisplatin Injection in the Neoadjuvant Treatment Locally Advanced EGFR-positive Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT04849377
RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC treatment 2 withdrawn NCT03735628
An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors treatment 1 completed NCT02764593
Safety Testing of Adding Nivolumab to Chemotherapy in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Cancer treatment 1 completed NCT05891171
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers treatment 1 recruiting NCT06482307
Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET No drug interventions diagnostic 1 / 2 not_yet_recruiting NCT05473156
A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies No drug interventions treatment 1 / 2 not_yet_recruiting NCT03811652
A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors No drug interventions treatment 1 completed NCT03276819
A Clinical and Biological Umbrella Protocol for Smoker or Non-smoker Patients With OPML or HNSCC No drug interventions prevention Not Available terminated NCT00911326
Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma diagnostic 3 terminated NCT03546582
SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma treatment 2 recruiting NCT03746431
A Phase 1/2 Study of [225Ac]-FPI-1434 Injection No drug interventions treatment 1 / 2 recruiting NCT03114280
Pembrolizumab and Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma (PICH Study) No drug interventions treatment 1 / 2 withdrawn NCT04284540
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma No drug interventions treatment Not Available recruiting NCT02277197
Ficlatuzumab and Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) other 1 completed NCT02649530
A Phase II Trial Evaluating WNT974 in Patients With Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 withdrawn NCT02993991
Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral Cavity treatment 1 withdrawn NCT02296684
Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT03575598
Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study treatment 0 completed NCT00903461
Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell Carcinoma No drug interventions treatment 1 terminated NCT02369458
Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard Therapies treatment 2 active_not_recruiting NCT02205398
Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy treatment 1 terminated NCT04424641
A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors No drug interventions treatment 1 / 2 terminated NCT04107103
Nivolumab Plus Pemetrexed for Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT04925284
Study of XB002 in Subjects With Solid Tumors (JEWEL-101) treatment 1 active_not_recruiting NCT02573259
A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors No drug interventions treatment 1 completed NCT01393184
Safety and Efficacy Study of Target Therapy Combined With Radiotherapy to Treat Senile Locally Advanced SCCHN treatment 2 unknown_status NCT03771820
Combination Therapy With NC-6004 and Pembrolizumab in Head and Neck Cancer Subjects Who Have Failed Platinum Regimen treatment 2 unknown_status NCT04595981
Chemo-embolization for Head and Neck Cancer treatment 2 not_yet_recruiting NCT02878655
Evaluation of the Overall Quality of Life After the Neck Dissection Retro-spinal Sector (IIb), in Squamous Cell Carcinomas Clinical and Radiological N0 VADS No drug interventions Not Available Not Available unknown_status NCT02624999
Study Comparing AlloVax™ to Chemotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head & Neck treatment 2 withdrawn NCT02834247
A Study of TAK-659 in Combination With Nivolumab in Participants With Advanced Solid Tumors other 1 terminated NCT03621982
Study of ADCT-301 in Patients With Selected Advanced Solid Tumors treatment 1 terminated NCT04989387
Study of INCA 0186 in Subjects With Advanced Solid Tumors treatment 1 active_not_recruiting NCT03538028
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies treatment 1 completed NCT02335918
A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors treatment 1 / 2 completed NCT01285635
A Study of AT-101 in Combination With Docetaxel in Squamous Cell Carcinoma Of The Head and Neck treatment 2 terminated NCT02499120
Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer treatment 2 completed NCT05057247
Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC treatment 2 active_not_recruiting NCT03405142
Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer diagnostic 2 completed NCT01204099
Study of PX-866 and Docetaxel in Solid Tumors treatment 1 / 2 completed NCT00392665
Bevacizumab/Tarceva and Tarceva/Sulindac in Squamous Cell Carcinoma of the Head and Neck treatment 2 terminated NCT04052204
Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors treatment 1 / 2 terminated NCT02001623
Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors treatment 1 / 2 completed NCT03396718
De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas No drug interventions treatment Not Available recruiting NCT01941992
Role of SAMITAL® in the Relief of Chemo-radiation (CT-RT) Induced Oral Mucositis in Head and Neck Cancer Patients No drug interventions treatment 2 completed NCT01927354
Study on the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family. No drug interventions Not Available Not Available unknown_status NCT05423197
Study Evaluating Zr-Panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous Cell Carcinoma diagnostic 2 not_yet_recruiting NCT04459715
A Study of Xevinapant (Debio 1143) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiotherapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy (TrilynX) treatment 3 terminated NCT04609566
Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors treatment 2 recruiting NCT06223568
Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer treatment 2 recruiting NCT06546553
A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines. treatment 1 recruiting NCT05208762
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors treatment 1 recruiting NCT05783622
Study of JANX008 in Subjects with Advanced or Metastatic Solid Tumor Malignancies No drug interventions treatment 1 recruiting NCT05930938
Study Comparing RT With Cetuximab + Xevinapant to RT With Cetuximab-placebo in Patients With Head and Neck Cancer treatment 3 suspended NCT05983133
A Study of SGN-EGFRd2 in Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT02765503
Resource Sparing Curative Radiotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck: The HYPNO Trial No drug interventions treatment Not Available unknown_status NCT03635164
Radiotherapy With Durvalumab Prior to Surgical Resection for HPV Negative Squamous Cell Carcinoma treatment 1 active_not_recruiting NCT06041464
Study of HLA-DR in Cell Cultures Isolated From Primary Squamous Cell Carcinoma No drug interventions Not Available Not Available unknown_status NCT06236464
Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas No drug interventions Not Available Not Available recruiting NCT03855384
Study of TQB2450 in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck（R/M SCCHN） treatment 3 unknown_status NCT03652077
A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies treatment 1 completed NCT00377247
Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor No drug interventions treatment 1 terminated NCT05931445
Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid Cancer No drug interventions treatment Not Available active_not_recruiting NCT02022098
Debio 1143-201 Dose-finding and Efficacy Phase I/II Trial treatment Not Available completed NCT03381183
IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma treatment 1 active_not_recruiting NCT00513383
Panitumumab Chemoradiotherapy Chemotherapy for Squamous Cancer of the Head and Neck treatment 1 completed NCT03129061
Study to Evaluate Immunological Response to PD-1 Inhibition in Squamous Cell Carcinoma of the Head and Neck (SCCHN) No drug interventions diagnostic 1 completed NCT03646461
Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC treatment 2 active_not_recruiting NCT02624128
Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and Neck treatment 2 active_not_recruiting NCT03843671
Hyperbaric Radiation Sensitization of Head and Neck Cancers No drug interventions treatment 2 not_yet_recruiting NCT02572778
Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer No drug interventions Not Available Not Available recruiting NCT02707588
Tolerance and Efficacy of Pembrolizumab or Cetuximab Combined With RT in Patients With Locally Advanced HNSCC treatment 2 completed NCT02124707
Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN treatment 2 completed NCT05068609
A Study of Nivolumab in Participants With Squamous Cell Carcinoma of the Head & Neck (SCCHN) - Patient Reported Outcomes (PRO) Not Available Not Available completed NCT01177956
A Trial to Determine the Safety and Anti-tumor Activity Profile of the Combination of Cetuximab and Concomitant Cisplatin Plus 5-Fluorouracil (5-FU) in Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma in Head and Neck treatment 3 completed NCT03629756
A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies treatment 1 completed NCT01344356
Stereotactic Body Radiotherapy for Head and Neck Tumors No drug interventions treatment 4 completed NCT03179956
Impact of Ribociclib on Head and Neck Squamous Cell Cancer basic_science 0 terminated NCT03246685
Phase 2 Study of Imprime PGG & Pembrolizumab in Subjects With Adv SCCHN Who Failed Pembro Monotherapy or Experiencing SD treatment 2 terminated NCT00901537
Azacitidine and Cisplatin in Patients With Advanced Lung or Head and Neck Cancer treatment 1 terminated NCT05329532
Modi-1 in Breast, Head and Neck, Ovarian, or Renal Cancer treatment 1 / 2 recruiting NCT02819752
PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck other 1 terminated NCT00999700
Induction Chemotherapy Followed by Cetuximab Plus Definitive Radiotherapy Versus Radiation Plus Cisplatin treatment 3 unknown_status NCT03071900
CTC Detection Rate in SCCHN With a in Vivo Device No drug interventions diagnostic Not Available unknown_status NCT02510859
Nutrition and Life QUality Patients With Head and Neck Cancers No drug interventions supportive_care Not Available completed NCT03513042
Early Response Evaluation of Proton Therapy by PET-imaging in Squamous Cell Carcinoma Located in the Head and Neck No drug interventions Not Available Not Available terminated NCT02054442
A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck treatment 1 / 2 unknown_status NCT02376699
Safety Study of SEA-CD40 in Cancer Patients treatment 1 terminated NCT02636036
Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors treatment 1 completed NCT02762513
Expansion Trial for Axitinib In Head And Neck Cancer treatment 2 completed NCT04152018
Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. No drug interventions treatment 1 active_not_recruiting NCT02452424
A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors treatment 1 / 2 terminated NCT01716416
Pazopanib Plus Cetuximab for Incurable Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 1 completed NCT02437916
Safety Study of AMG 228 to Treat Solid Tumors No drug interventions treatment 1 terminated NCT01012258
Cetuximab With Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck in Chinese Subjects treatment 3 completed NCT01528163
Study Comparing Two Treatments in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT03690986
VX15/2503 in Combination With Ipilimumab or Nivolumab in Patients With Head and Neck Cancer treatment 1 recruiting NCT01379339
Cabazitaxel - PF Induction Chemotherapy treatment 1 completed NCT01218048
ERBITUX® Followed by Adjuvant Treatment With Chemoradiation and ERBITUX® for Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT03712566
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy No drug interventions Not Available Not Available active_not_recruiting NCT03325465
Neoadjuvant Pembrolizumab + Epacadostat Prior to Curative Surgical Care for Squamous Cell Carcinoma of the Head and Neck treatment 2 withdrawn NCT03148665
Saliva-based Detection of CD44 No drug interventions Not Available Not Available completed NCT02769520
Efficacy Study of Pembrolizumab in Relapsed, Locally Recurrent Squamous Cell Cancer of the Head and Neck treatment 2 active_not_recruiting NCT02139020
Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients No drug interventions Not Available Not Available recruiting NCT02002182
ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer treatment 2 completed NCT02473731
A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients No drug interventions treatment 1 completed NCT01758731
Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History treatment 1 completed NCT03624231
Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC treatment 2 completed NCT02538627
Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib treatment 1 terminated NCT01967927
Understanding GRID Radiation Therapy Effects on Human Tumor Oxygenation and Interstitial Pressure to Increase Translation of Solid Tumor Therapy diagnostic 0 withdrawn NCT02543476
SUPREME-HN A Retrospective Cohort Study of PD-L1 in Recurrent and Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN) No drug interventions Not Available Not Available completed NCT04191460
Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer No drug interventions diagnostic 2 recruiting NCT01051791
Phase II Study of RAD001 Head and Neck Cancer treatment 2 terminated NCT01133262
Effectiveness in Head and Neck Cancer Detection Using Positron Emission Tomography (PET) Insert Device No drug interventions Not Available Not Available withdrawn NCT05459129
A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer) treatment 1 / 2 completed NCT04830592
A Study of NG-641 and Pembrolizumab in Squamous Cell Carcinoma of the Head and Neck treatment 1 active_not_recruiting NCT03525392
Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. treatment 1 terminated NCT01458392
Study of Dalantercept in Patients With Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT00736944
Trial of 2 Cycles of Induction Chemo With Abraxane, Cetuximab, Cisplatin, & 5-FU for Advanced Head and Neck Cancer treatment 2 completed NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation No drug interventions Not Available Not Available recruiting NCT01732640
A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC. treatment 1 / 2 terminated NCT03723967
FRAIL-IMMUNE (GORTEC 2018-03) - Combination of Durvalumab With Carboplatin/Paclitaxel treatment 2 completed NCT05835804
Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers No drug interventions treatment 2 not_yet_recruiting NCT02575404
GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients treatment 1 completed NCT03076372
A Study Evaluating MM-310 in Patients With Solid Tumors No drug interventions treatment 1 unknown_status NCT01305772
Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN treatment 2 terminated NCT04672772
Cetuximab Plus Paclitaxel as First Line for Recurrent and/or Metastatic SCCHN: Real World Data. Not Available Not Available completed NCT04659369
Study of Pharmacokinetic, Safety, Immunogenicity and Efficacy of CMAB819 and Nivolumab in R/M HNSCC treatment 1 terminated NCT03938012
Evaluating Mutations in MET and TP53 Among Patients Diagnosed With Squamous Cell Carcinoma No drug interventions Not Available Not Available unknown_status NCT01820312
A Phase II Study to Evaluate Low-Dose Fractionated Radiotherapy (LDFRT) No drug interventions treatment 2 withdrawn NCT02350712
Patritumab With Cetuximab and a Platinum Containing Therapy for Patients With Head and Neck Cancer treatment 1 completed NCT05751512
A Study to Evaluate MRG003 vs Cetuximab/Methotrexate in in the Treatment of Patients With RM-SCCHN treatment 3 not_yet_recruiting NCT03917381
GEN1046 Safety Trial in Patients With Malignant Solid Tumors treatment 1 / 2 active_not_recruiting NCT03758781
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors treatment 1 completed NCT03160495
Functional ImaGing of Heterogeneity in Head and Neck Tumors - Validation From Surgical Specimens No drug interventions Not Available Not Available completed NCT00442455
Erlotinib,Radiation and Cisplatin in Patients With Complete Resected Squamous Cell Carcinoma of the Head and Neck treatment 3 completed NCT02124850
A Phase Ib Study of Neoadjuvant of Cetuximab Plus Motolimod and Cetuximab Plus Motolimod Plus Nivolumab treatment 1 terminated NCT02031250
Randomized Phase II Study of DCE-MRI-based Dose Escalation for Poor-prognosis and Neck Cancer treatment 2 active_not_recruiting NCT01737008
Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and Neck treatment 1 completed NCT01015664
Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 1 / 2 terminated NCT02435602
The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers No drug interventions screening Not Available completed NCT02454179
Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT01783587
Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer treatment 1 completed NCT01612351
Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery treatment 2 active_not_recruiting NCT03454451
CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers treatment 1 completed NCT01221753
Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study treatment 2 terminated NCT04881045
Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors. No drug interventions treatment 1 completed NCT03752398
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) treatment 1 completed NCT06285097
A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors treatment 1 recruiting NCT03645928
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors treatment 2 recruiting NCT02573493
Nab-Paclitaxel and Cisplatin or Nab-paclitaxel as Induction Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (HNSCC) treatment 2 active_not_recruiting NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors treatment 1 completed NCT00625456
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors treatment 1 completed NCT01830556
Randomised Phase II, Cetuximab in Combination With 5FU and Cisplatin or Carboplatin Versus Cetuximab in Combination With Paclitaxel and Carboplatin for Treatment of Patients With Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 2 unknown_status NCT03830385
Paclitaxel (Albumin Bound),Bleomycin And Cisplatin Or Carboplatin for Recurrent Or Metastatic Squamous Cell Carcinoma Of The Head And Neck treatment 2 recruiting NCT03944915
De-Escalation Therapy for Human Papillomavirus Negative Disease treatment 2 recruiting NCT01386632
Study of DCA (Dichloroacetate) in Combination With Cisplatin and Definitive Radiation in Head and Neck Carcinoma treatment 2 completed NCT00971932
Study of Cetuximab in Combination With Chemotherapy in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) treatment 2 completed NCT00206752
Study of Unilateral Neck Irradiation in Patients With SCC of the Head and Neck No drug interventions treatment Not Available completed NCT02551159
Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer treatment 3 completed NCT00210470
A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer treatment 2 completed NCT04787042
Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067 treatment 1 / 2 active_not_recruiting NCT01998542
Safety and Tolerability Study of AlloVax(TM) in Patients With Metastatic or Recurrent Cancer of the Head and Neck No drug interventions treatment 2 completed NCT03330249
Comparison of Two Concomitant Administration of RT With Cisplatin in Standard Infusion or Fractional Infusion treatment 2 completed NCT02105636
Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Head and Neck Carcinoma (CheckMate 141) treatment 3 completed NCT03245736
Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors. treatment 2 completed NCT03341936
Neodjuvant Nivolumab and Lirilumab, Followed by Surgery, Followed by Adjuvant Nivolumab and Lirilumab, in SCCHN treatment 2 active_not_recruiting NCT00652613
Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) No drug interventions treatment 2 unknown_status NCT03057613
The Addition of Pembrolizumab to Postoperative Radiotherapy in Cutaneous Squamous Cell Cancer of the Head and Neck treatment 2 completed NCT03894618
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas No drug interventions treatment 1 completed NCT01488318
Cetuximab and Dasatinib in Recurrent Squamous Cell Carcinoma treatment 2 terminated NCT00206219
Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX) treatment 3 completed NCT02262741
A Phase I Study to Evaluate the Safety, Tolerability and Efficacy of MEDI4736 (Durvalumab) With Tremelimumab in Head and Neck Cancer treatment 1 completed NCT02158234
Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck treatment 1 completed NCT02812524
Ipilimumab for Head and Neck Cancer Patients treatment 1 active_not_recruiting NCT02972216
Post-marketing Surveillance Study of Docetaxel-Based Chemotherapy Not Available Not Available completed NCT03880396
Definitive Concurrent Hypofractionated Rth With Weekly Cisplatin in Locally Advanced SCCHN No drug interventions Not Available Not Available completed NCT02565758
ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors No drug interventions treatment 1 completed NCT03946358
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL) treatment 2 active_not_recruiting NCT03139058
Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck No drug interventions other Not Available unknown_status NCT02628535
Safety Study of MGD009 in B7-H3-expressing Tumors No drug interventions treatment 1 terminated NCT04590963
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer treatment 3 active_not_recruiting NCT01415986
Interstitial Photodynamic Therapy (PDT) With Temoporfin for Advanced Head and Neck Cancers treatment 2 terminated NCT02952586
Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100) treatment 3 terminated NCT01104922
Re-irradiation With Fractionated Stereotactic Radiosurgery Plus Cetuximab in Patients With Recurrent Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT04034225
Addition of SNS-301 to Checkpoint Inhibitor Treatment in Metastatic/Recurrent SCCHN treatment 1 / 2 terminated NCT02841748
A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study treatment 2 active_not_recruiting NCT04326257
Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy treatment 2 active_not_recruiting NCT03862066
Memory Phenotype and PD-1 Inhibition Response in Oral Cancer No drug interventions Not Available Not Available terminated NCT03552965
Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC No drug interventions supportive_care Not Available active_not_recruiting NCT00570674
Abraxane in Combination With Carboplatin, Erbitux and IMRT for Locally Advanced Squamous Cancer of the Head and Neck treatment 1 / 2 terminated NCT03194373
Phase II Trial Evaluating the Efficacy of Palbociclib in Combination With Carboplatin for the Treatment of Unresectable Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT03202173
The Diagnosis of NPC Using the Probe-based Confocal Laser Endomicroscopy No drug interventions diagnostic Not Available unknown_status NCT03083873
Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & Neck treatment 2 completed NCT01360827
EMD 1201081 + 5-FU + Cisplatin + Cetuximab in Subjects With Recurrent / Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 1 terminated NCT03098160
Immunotherapy Study of Evofosfamide in Combination With Ipilimumab treatment 1 unknown_status NCT01774760
Reproducibility of Intratumor Distribution of 18F-EF5 in Head and Neck Cancer No drug interventions diagnostic 2 completed NCT04628780
Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors No drug interventions treatment 1 terminated NCT02429089
Study of LEE011plus Cetuximab in Patients With a Cancer of the Head and Neck treatment 1 terminated NCT02352792
Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer No drug interventions treatment Not Available unknown_status NCT01984892
Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC) treatment 2 terminated NCT03689192
Arginase-1 Peptide Vaccine in Patients With Metastatic Solid Tumors No drug interventions treatment 1 completed NCT03313804
Priming Immunotherapy in Advanced Disease With Radiation No drug interventions treatment 2 active_not_recruiting NCT02510872
Performance of PET 18 F-FDG Coupled to CT With Contrast Injection Iodized in the Diagnosis of Early Recurrences of Head and Neck Carcinoma Treated With Concurrent Chemoradiation. Comparison With 18F-FDG PET Coupled With CT Not Injected With Filling CT Standard Injection No drug interventions diagnostic Not Available completed NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors treatment 1 completed NCT04453046
Hemopurifier Plus Pembrolizumab in Head and Neck Cancer treatment Not Available terminated NCT04290546
CIML NK Cell in Head & Neck Cancer treatment 1 recruiting NCT03349710
Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck Cancer treatment 3 completed NCT03633110
Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccine treatment 1 / 2 completed NCT03733210
Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer diagnostic 1 completed NCT00272181
Study of Proxinium for Treating Patients With Squamous Cell Head and Neck Cancer treatment 2 terminated NCT05123950
A Study of Treatment Patterns and Clinical Outcomes in First Line Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (1L R/M SCCHN) Participants in Europe No drug interventions Not Available Not Available completed NCT02686008
Pharmacodynamic Study to Assess the Anti-proliferative Activity of the PARP Inhibitor Olaparib in Patients With HPV Positive and HPV Negative HNSCC treatment 1 withdrawn NCT02882308
Preoperative Administration of Olaparib With Cisplatin or With Durvalumab or Alone or no Tratment in Patients Who Are Candidates for Surgery of Carcinoma of the Head and Neck. treatment 2 completed NCT00257738
0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck No drug interventions treatment 1 completed NCT04545827
Study to Evaluate the Safety of IMM-01 in Patients With Advanced Solid Tumours basic_science 1 not_yet_recruiting NCT02383927
Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations treatment 2 completed NCT06597565
A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC treatment 2 recruiting NCT03498378
Avelumab, Cetuximab, and Palbociclib in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 1 active_not_recruiting NCT04139057
EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC No drug interventions treatment 1 / 2 suspended NCT04291105
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients treatment 2 recruiting NCT04369937
HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05172258
Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck treatment 2 recruiting NCT05879484
Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS treatment 1 / 2 not_yet_recruiting NCT06305247
A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours No drug interventions treatment 1 / 2 recruiting NCT06496178
A Phase 3 Study to Evaluate Petosemtamab Compared with Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients treatment 3 recruiting NCT04721223
JAB-3068 Activity in Adult Patients With Advanced Solid Tumors treatment 1 / 2 completed NCT04722523
A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer treatment 1 recruiting NCT04977453
GI-101 As a Single Agent or in Combination with Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors treatment 1 / 2 recruiting NCT05239143
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT05420948
A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer treatment 2 recruiting NCT05544136
A Study of Decreasing Radiation Therapy and Chemotherapy in People with Head and Neck Cancer treatment 2 recruiting NCT05551117
A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors treatment 2 active_not_recruiting NCT05635643
Study of CHS-114 in Participants With Advanced Solid Tumors treatment 1 recruiting NCT05714553
NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours treatment 1 / 2 recruiting NCT05877599
A Study of NT-175 in Adult Subjects with Unresectable, Advanced, And/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation No drug interventions treatment 1 recruiting NCT05902988
A Phase I/II Study of VLS-1488 in Subjects with Advanced Cancer No drug interventions treatment 1 / 2 recruiting NCT05996432
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy No drug interventions diagnostic 0 recruiting NCT06022029
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. treatment 1 recruiting NCT06054477
Study of ALE.C04 in Patients With Head and Neck Cancer treatment 1 / 2 recruiting NCT06147037
A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients with Advanced Solid Tumours No drug interventions treatment 1 recruiting NCT06159621
CD40 Agonist and PD-1 Inhibitor in HNSCC No drug interventions treatment 1 recruiting NCT06238479
A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT06248996
a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients No drug interventions treatment 3 recruiting NCT06308913
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma treatment 0 recruiting NCT06444815
A Study of VET3-TGI in Patients With Solid Tumors treatment 1 recruiting NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors No drug interventions treatment 1 recruiting NCT06535607
Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors treatment 2 recruiting NCT06601335
A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) treatment 3 not_yet_recruiting NCT06477003
Multispectral Optoacoustic Tomography in Head and Neck Squamous Cell Cancer No drug interventions diagnostic Not Available not_yet_recruiting NCT05005403
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of ABBV-514 Alone or in Combination With Budigalimab treatment 1 recruiting NCT05867303
A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT03650764
Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma treatment 1 / 2 active_not_recruiting NCT03267121
A Study of Apatinib and Tegafur Gimeracil Oteracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT01045421
Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignancies treatment 1 / 2 completed NCT06062602
PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC basic_science 0 completed NCT05213884
The Efficacy of Induction and Adjuvant Camrelizumab Combined With Chemoradiation for LA-HNSCC treatment 2 recruiting NCT06532279
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer supportive_care 2 not_yet_recruiting NCT03878979
Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN treatment 2 completed NCT04675333
Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04) treatment 2 active_not_recruiting NCT02507154
Reactivating NK Cells in Treating Refractory Head and Neck Cancer treatment 1 / 2 unknown_status NCT03618654
Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma treatment 0 completed NCT03258554
Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin treatment 2 / 3 active_not_recruiting NCT05821751
The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors treatment Not Available recruiting NCT03993353
Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer treatment 2 recruiting NCT05267353
Develop and Test the 'Multi-Faced Continuous Exercise Program' in Operable Head and Neck Cancer Patients No drug interventions supportive_care Not Available unknown_status NCT00957853
Preoperative Treatment With Cetuximab and/or IMC-A12 treatment 2 completed NCT04868877
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination treatment 1 / 2 recruiting NCT03865277
Individualized Radiation Dose Prescription in HNSCC Based on F-MISO-PET Hypoxia-Imaging No drug interventions treatment 2 not_yet_recruiting NCT00634777
Assessment of Regional Response With PET-FDG in Advanced Head and Neck Squamous Cell Carcinoma No drug interventions diagnostic Not Available unknown_status NCT06162377
Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study. treatment 4 recruiting NCT03389477
Los Tres Paso: Neoadjuvant Palbociclib Monotherapy, Concurrent Chemoradiation Therapy, Adjuvant Palbociclib Monotherapy in Patients With p16INK4a Negative, HPV-Unrelated Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05952947
HRYZ-T101 Injection for HPV18 Positive Solid Tumor treatment 1 recruiting NCT03406247
Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT05901545
Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer treatment 1 recruiting NCT06366945
Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC treatment 2 not_yet_recruiting NCT01377298
Pazopanib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 unknown_status NCT04843098
Study of TL117 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 1 / 2 unknown_status NCT03283605
Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas treatment 1 / 2 active_not_recruiting NCT05338905
Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial No drug interventions basic_science Not Available recruiting NCT06100497
Efficacy and Safety of PD-1 Plus Chemotherapy in Poorly Differentiated Locally Advanced (LA) HNSCC treatment 2 recruiting NCT02255097
Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055) treatment 2 completed NCT06451497
Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors No drug interventions other 1 recruiting NCT03789097
Vaccination With Flt3L, Radiation, and Poly-ICLC treatment 1 / 2 recruiting NCT05238883
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors treatment 1 recruiting NCT04523883
Concurrent Immunotherapy With Postoperative Radiotherapy in Intermediate/High Risk HNSCC Patients Unfit for Cisplatin: The IMPORT Study (IMPORT) treatment 2 unknown_status NCT03602911
A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients diagnostic 2 recruiting NCT05364411
HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC No drug interventions treatment Not Available recruiting NCT06307093
Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms treatment 1 active_not_recruiting NCT06199271
Neoadjuvant Adebrelimab Plus Dalpiciclib in Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT02318771
Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer treatment 1 completed NCT05219578
RTX-224 Monotherapy in Patients With Solid Tumors No drug interventions treatment 1 / 2 terminated NCT03817307
Validation of USPIO-enhanced MRI for Detection of Lymph Node Metastases in Head and Neck Carcinoma No drug interventions diagnostic Not Available unknown_status NCT06383507
A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors No drug interventions treatment 1 not_yet_recruiting NCT04254107
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer treatment 1 terminated NCT05977907
Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN). treatment 2 recruiting NCT05122507
Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva No drug interventions Not Available Not Available recruiting NCT05145907
Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors treatment 2 active_not_recruiting NCT04938609
Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC) treatment 2 recruiting NCT04567056
Specific Methylation Profiles in HNSCC No drug interventions Not Available Not Available recruiting NCT06194656
Clinical Trial of SIBP-03 in Patients With Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT03665285
A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 / 2 completed NCT04399785
Phase II Study for Combination of Camrelizumab and SBRT in the First-line Treatment for R/M HNSCC No drug interventions treatment 2 unknown_status NCT04555837
Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer treatment 1 / 2 active_not_recruiting NCT00174837
TRACE: Tirapazamine-Radiation And Cisplatin Evaluation treatment 3 completed NCT05098132
Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumors treatment 1 recruiting NCT04452032
Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer No drug interventions prevention 2 active_not_recruiting NCT02752932
TumorGraft- Guided Therapy for Improved Outcomes in Head and Neck Squamous Cell Cancer- A Feasibility Study No drug interventions supportive_care Not Available completed NCT04244552
A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies treatment 1 terminated NCT05294900
Trial of Neoadjuvant Therapy With Paclitaxel and Carboplatin in Operable Locally Advanced Head and Neck Cancer Patients treatment 2 unknown_status NCT04999800
Study of Pembrolizumab Combined With Anlotinib in the First Line Therapy for R/M HNSCC With CPS≥1 treatment 2 unknown_status NCT03182959
Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer No drug interventions prevention 0 completed NCT05945875
Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer diagnostic 1 recruiting NCT04060342
GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma treatment 1 terminated NCT05520099
Observational Basket Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform No drug interventions Not Available Not Available recruiting NCT04152499
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies treatment 1 / 2 recruiting NCT03578406
HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer No drug interventions treatment 1 unknown_status NCT02531906
Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation supportive_care 1 completed NCT05472506
Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer treatment 1 withdrawn NCT06508606
AK117 (Anti-CD47) + Anti-EGFR for R/M HNSCC treatment 2 not_yet_recruiting NCT03336606
Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma treatment 1 active_not_recruiting NCT06289049
Heavy Strength Training in Head and Neck Cancer Survivors No drug interventions other 2 not_yet_recruiting NCT04110249
Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer No drug interventions diagnostic Not Available terminated NCT05668949
Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 1 / 2 not_yet_recruiting NCT05858736
Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT02990936
Prognostic Impact of Tumor Growth Velocity in Head and Neck Squamous Cell Carcinoma Treated by Radio(Chemo)Therapy No drug interventions Not Available Not Available not_yet_recruiting NCT02608736
Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid prevention 0 completed NCT06142318
Pirfenidone as a Radiosensitizer in the Treatment of Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT02881918
Anti-tumor Specific Immune Response in Head and Neck Cancers No drug interventions Not Available Not Available unknown_status NCT03049618
Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 treatment 2 active_not_recruiting NCT05024019
Nimotuzumab Combined With Radiotherapy in High-risk Patients With HNSCC Not Suitable for Cisplatin After Surgery treatment 2 not_yet_recruiting NCT01711541
Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer treatment 1 / 2 completed NCT04440917
Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma treatment 2 unknown_status NCT04119024
Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors treatment 1 recruiting NCT04848116
Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca treatment 2 recruiting NCT05008796
PD-L1 Expression on CTCs in HNSCC Patients Underwent Curative CCRT No drug interventions Not Available Not Available unknown_status NCT03340896
Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT treatment 3 active_not_recruiting NCT05136196
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study treatment 2 suspended NCT04724096
Evaluation of OE-MRI in Patients With H&N Cancer No drug interventions Not Available Not Available completed NCT05674396
3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial No drug interventions treatment 2 recruiting NCT02495896
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors treatment 1 terminated NCT05993858
Neoadjuvant PD-1 Inhibitor Combined With Cetuximab in Operable Locally Advanced HNSCC treatment 2 not_yet_recruiting NCT05393635
ITIL-168 in Advanced Solid Tumors No drug interventions treatment 1 withdrawn NCT03526835
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors treatment 1 / 2 recruiting NCT02432963
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy treatment 1 active_not_recruiting NCT05291663
Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and Neck No drug interventions Not Available Not Available unknown_status NCT01644786
The Head and Neck Tumor Biobank No drug interventions Not Available Not Available active_not_recruiting NCT00620139
Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma Not Available Not Available completed NCT02207439
Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck diagnostic 2 completed NCT06437522
A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors No drug interventions treatment 2 recruiting NCT02567422
Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer treatment 1 active_not_recruiting NCT04003025
Body Composition and Prognosis in Head and Neck Squamous Cell Carcinoma (HNSCC) No drug interventions Not Available Not Available withdrawn NCT03775525
Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancer treatment 1 active_not_recruiting NCT05183048
Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma diagnostic 0 recruiting NCT03519048
Multicentric Comparative Study Between a Conventional and an Intensive Follow up Strategy After Treatment of a Head and Neck Squamous Cell Carcinoma No drug interventions other 3 active_not_recruiting NCT03386357
Radiotherapy With Pembrolizumab in Metastatic HNSCC treatment 2 active_not_recruiting NCT01086826
Treatment of Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck treatment 3 completed NCT05499065
Real-time Margin Assessment in Head and Neck Cancer treatment 2 recruiting NCT05476965
Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT04260074
Epigenetic Changes in Head and Neck Cancer No drug interventions Not Available Not Available completed NCT05107674
A Study of NX-1607 in Adults With Advanced Malignancies treatment 1 recruiting NCT01154920
Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT06239220
PD-L1 t-haNK, N-803 IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC treatment 2 recruiting NCT02003482
Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer No drug interventions Not Available Not Available completed NCT03153982
Ruxolitinib in Operable Head and Neck Cancer treatment 2 completed NCT04803331
SPIO-enhanced MRI in Oral Cancer for Sentinel Lymph Node Identification No drug interventions diagnostic Not Available unknown_status NCT04357873
Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations treatment 2 active_not_recruiting NCT06081673
Penpulimab Combined With Chemotherapy for Neoadjuvant and Adjuvant Therapy in Patients With Resectable HNSCC treatment 2 recruiting NCT03433027
A Study of BB-401 in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 completed NCT03317327
REirradiation and Programmed Cell Death Protein 1 (PD-1) Blockade On Recurrent Squamous Cell Head and Neck Tumors treatment 1 / 2 recruiting NCT03370276
Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma treatment 1 / 2 active_not_recruiting NCT01727076
Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer treatment 1 completed NCT05451576
Sodium Selenite Supplementation in Patients With Head and Neck Cancer No drug interventions supportive_care Not Available recruiting NCT02778191
Comparison of Concomitant Cisplatin Versus Carboplatin and 5-fluorouracil With Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma Not Available Not Available completed NCT00765791
2B or Not 2B? Shoulder Function After Level 2B Neck Dissection: A Randomized Controlled Study No drug interventions treatment Not Available completed NCT05889091
A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment No drug interventions treatment Not Available recruiting NCT03424291
A Retrospective Clinical Study of Apatinib in Combination With Radiotherapy / Chemotherapy Second-line and Above in the Treatment of Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 unknown_status NCT02706691
BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer treatment 2 terminated NCT01846091
Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancer treatment 1 completed NCT02365662
A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor No drug interventions treatment 1 terminated NCT06576180
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma Not Available Not Available recruiting NCT02544880
PDE5 Inhibition Via Tadalafil to Enhance Anti-Tumor Mucin 1 (MUC1) Vaccine Efficacy in Patients With HNSCC treatment 1 completed NCT04000529
Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies treatment 1 terminated NCT06007729
ARTEMIS-006: HS-20093 in Patients With Head and Neck Squamous Cell Carcinoma and Other Solid Tumors No drug interventions treatment 2 recruiting NCT02488629
Study of SCB01A in Patient With Head and Neck Cancer treatment 2 terminated NCT02593929
Pharmacodynamic Effects and Predictive Biomarkers With Ruxolitinib in Operable Head and Neck Cancer treatment 0 withdrawn NCT04278092
Paclitaxel Plus Cetuximab After First-line Checkpoint Inhibitor Failure treatment 2 recruiting NCT01852292
Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy treatment 2 terminated NCT04807140
Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002) treatment 2 recruiting NCT04414540
Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients treatment 2 active_not_recruiting NCT04464967
Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers treatment 1 / 2 withdrawn NCT03228667
QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors treatment 2 active_not_recruiting NCT03450967
Durvalumab Plus Tremelimumab Combined With Proton Therapy for HNSCC treatment 2 unknown_status NCT02047201
Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC treatment 2 completed NCT02892201
Pembrolizumab in HNSCC With Residual Disease After Radiation treatment 2 terminated NCT03838601
Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 No drug interventions treatment Not Available active_not_recruiting NCT05909904
Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT04199104
A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010) treatment 3 active_not_recruiting NCT05094804
A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents treatment 1 / 2 recruiting NCT02178072
Window Trial 5-aza in HNSCC, T-tare treatment 1 completed NCT03926468
Liquid Biopsy in Head and Neck Cancer No drug interventions Not Available Not Available unknown_status NCT05143268
Acupuncture for Dysphagia in Head and Neck Squamous Cell Carcinoma No drug interventions Not Available Not Available recruiting NCT04681469
Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCC treatment 2 recruiting NCT03094169
AVID100 in Advanced Epithelial Carcinomas No drug interventions treatment 1 / 2 terminated NCT06323369
Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma prevention 2 recruiting NCT05743569
3D Specimen Maps for RT Planning No drug interventions Not Available Not Available recruiting NCT03134846
Image Guided Surgery for Margin Assessment of Head and Neck Cancer Using Cetuximab-IRDye800CW cONjugate diagnostic 1 / 2 unknown_status NCT02508246
WEE1 Inhibitor MK-1775, Docetaxel, and Cisplatin Before Surgery in Treating Patients With Borderline Resectable Stage III-IVB Squamous Cell Carcinoma of the Head and Neck treatment 1 completed NCT04694846
Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use prevention Not Available active_not_recruiting NCT02999646
Personalized and Cell-based Antitumor Immunization MVX-ONCO-1 in Advanced HNSCC No drug interventions treatment Not Available completed NCT05065346
Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC No drug interventions treatment Not Available not_yet_recruiting NCT03896412
Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma No drug interventions other Not Available unknown_status NCT03795610
Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT06170710
Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC treatment 2 recruiting NCT01794481
Benefits of Exercise Training in Head and Neck Cancer Patients Undergoing Organ-Preserving Definitive Therapy No drug interventions treatment Not Available completed NCT06088381
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) No drug interventions treatment 2 recruiting NCT04146181
Safety and Efficacy of SCT-I10A in Head and Neck Squamous Cell Carcinoma treatment 2 unknown_status NCT05964595
Temporal Diffusion Spectroscopy MRI in Predicting the CPS of PD-L1 Expression and the Efficacy of Neoadjuvant Therapy No drug interventions Not Available Not Available recruiting NCT06494995
AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy treatment 2 not_yet_recruiting NCT02270814
Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT04413214
Carrimycin in Patients With Locally Advanced, Recurrent, or Metastatic HNSCC (Non NPC): A Phase I Trial treatment 1 completed NCT05827614
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications treatment 1 recruiting NCT05229614
Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease treatment 2 recruiting NCT01696955
Cetuximab With or Without Tivantinib in Treating Patients With Head and Neck Cancer That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery treatment 2 completed NCT06251050
A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy prevention 1 / 2 not_yet_recruiting NCT05523323
A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (LEAP-010) (MK-7902-010)-China Extension Study treatment 3 active_not_recruiting NCT05854823
The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR No drug interventions treatment Not Available recruiting NCT02582008
Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy prevention 0 terminated NCT03744208
SCT200 Injection in Patients With Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT04164238
Neoadjuvant Anti-PD-1 Antibody (Toripalimab) or Combined With Chemotherapy in HNSCC Patients treatment 2 unknown_status NCT05117138
Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors No drug interventions treatment 1 / 2 unknown_status NCT05941338
Tirelizumab in Combination With Carboplatin and Albumin-binding Paclitaxel for Neoadjuvant Therapy in HNSCC treatment 2 recruiting NCT04001543
Efficacy of an Oral Immunomodulatory Nutrient on Survival During Postoperative Concomitant Chemoradiotherapy in Head and Neck Cancer No drug interventions treatment Not Available active_not_recruiting NCT03196843
Radiotherapy Combine With Raltitrexed Versus Radiotherapy Alone in Older Patients With HNSCC. treatment 4 unknown_status NCT02643303
A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers treatment 1 / 2 completed NCT06422403
A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers No drug interventions treatment 2 not_yet_recruiting NCT05299203
BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma) prevention 1 unknown_status NCT05919290
HN-QUEST: A Study of Head and Neck Imaging Biomarkers No drug interventions other Not Available recruiting NCT05582590
Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers treatment 1 not_yet_recruiting NCT04490564
Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma No drug interventions Not Available Not Available active_not_recruiting NCT03169764
QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy treatment 1 / 2 withdrawn NCT04857164
Study of Pembrolizumab Combined With Chemotherapy in the First Line Therapy for R/M HNSCC in China treatment 2 completed NCT06150664
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies No drug interventions treatment 1 recruiting NCT05936502
Ascertaining the Radiologic Prognostic Importance of Extranodal Extension on Imaging (iENE) in Head and Neck Cancer No drug interventions Not Available Not Available completed NCT04146402
SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma treatment 3 unknown_status NCT04752384
Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients supportive_care 2 active_not_recruiting NCT03096184
A Study of Apatinib Plus Tegafur Gimeracil Oteracil in Recurrent/Metastatic Head and Neck Cancers treatment 2 unknown_status NCT02678884
Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study diagnostic Not Available recruiting NCT05189184
Study of Camrelizumab in Combination With Apatinib Mesylate Plus Albumin-bound Paclitaxel and Cisplatin as the First Line Treatment of Recurrent or Metastatic, UnresectableHead and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT04375384
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer treatment 2 recruiting NCT04826679
Neoadjuvant Camrelizumab in Combination With Cisplatin and Nab-paclitaxel in Resectable HNSCC treatment 2 recruiting NCT06047379
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis treatment 1 / 2 recruiting NCT05965154
Calizumab Combined With Bevacizumab and Capecitabine in the Treatment of Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT03983954
Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumors treatment 1 active_not_recruiting NCT05793151
Multi-Site Trial of Navigation vs Treatment as Usual for Delays in Starting Adjuvant Therapy No drug interventions health_services_research Not Available recruiting NCT06366451
PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC basic_science 0 recruiting NCT06528353
Blood Biomarkers Based Screening for HPV-driven OPC No drug interventions screening Not Available not_yet_recruiting NCT06378177
A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 2 recruiting NCT04099277
A Study of LY3435151 in Participants With Solid Tumors treatment 1 terminated NCT05576077
A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors treatment 1 recruiting NCT05156177
Correlation of Fecal Microbiome and Its Metabolites With Outcome of Radiotherapy in Head and Neck Carcinoma No drug interventions Not Available Not Available active_not_recruiting NCT01484847
A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma diagnostic Not Available completed NCT06084845
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer treatment 2 withdrawn NCT05363605
A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours treatment 1 / 2 terminated NCT06509997
A Phase II Study of Anti-EGFR Antibody-drug Conjugate (ADC) Combine With CDK4/6 Inhibitors Posterior Line in the Treatment of Recurrent/Metastatic CDKN2A Gene Variant Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT03474497
UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade treatment 1 / 2 recruiting NCT06170697
Advanced First-line Treatment of Short-term Postoperative Progression of Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT05044897
A Clinical Study to Evaluate the Efficacy and Safety of SI-B001 in the Treatment of Recurrent and Metastatic HNSCC No drug interventions treatment 2 recruiting NCT05645783
Liquid Biopsy for Early DiagNosis of Squamous Cell Carcinoma of the HeAd and NeCk rEgion No drug interventions Not Available Not Available recruiting NCT05176483
Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors treatment 1 recruiting NCT02901483
A Study of PEP503 With Radiotherapy in Combination With Concurrent Chemotherapy for Patients With Head and Neck Cancer treatment 1 / 2 terminated NCT03053661
Immune Response Evaluation to Curative Conventional Therapy No drug interventions Not Available Not Available unknown_status NCT03463161
Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy treatment 2 terminated NCT05432193
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER) treatment 1 active_not_recruiting NCT04193293
A Study of Duvelisib in Combination With Pembrolizumab in Head and Neck Cancer treatment 1 / 2 terminated NCT06011993
Real-world Analysis on the Efficacy and Safety of Neoadjuvant Therapy for Head and Neck Squamous Cell Carcinoma （neoHNSCC） No drug interventions Not Available Not Available recruiting NCT06578871
Surgery and Reducing Ionizing Radiation of the Unknown Primary No drug interventions treatment 2 not_yet_recruiting NCT03518671
Building a Renewed ImaGe After Head & Neck Cancer Treatment No drug interventions supportive_care Not Available completed NCT05457478
The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy No drug interventions supportive_care Not Available recruiting NCT01427478
Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and Neck treatment 3 completed NCT02862678
Predictive Value of Diffusion-weighted MRI Performed in Early Post-treatment in the Occurrence of Tumor Recurrence or Progression in Head and Neck Squamous Cell Carcinoma Treated With Chemoradiotherapy: a Pilot Study No drug interventions diagnostic Not Available completed NCT05707078
PET/CT Follow up for Head and Neck Squamous Cell Carcinoma No drug interventions treatment Not Available recruiting NCT01975688
A Pharmacokinetic Study of Single Doses of Sativex in Treatment-induced Mucositis treatment 1 terminated NCT05913388
GB1211 and Pembrolizumab Versus Pembrolizumab and Placebo in Patients With Metastatic Melanoma and Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT06109207
Neoadjuvant Camrelizumab With Dalpiciclib for Resectable Head and Neck Squamous Cell Carcinomas treatment 1 recruiting NCT03022409
A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC). treatment 1 completed NCT04599309
Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma No drug interventions Not Available Not Available active_not_recruiting NCT05077709
IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC treatment 2 active_not_recruiting NCT06444009
A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT03740256
Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors No drug interventions treatment 1 recruiting NCT02777385
Pembrolizumab in Combination With Cisplatin and Intensity Modulated Radiotherapy (IMRT) in Head and Neck Cancer treatment 2 completed NCT04196985
18F-FDG PET/CT Versus 18F-FDG PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC No drug interventions diagnostic Not Available recruiting NCT05522985
Neoadjuvant Chemotherapytreatment of Locally Advanced Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 recruiting NCT04969315
TT-10 as a Single Agent in Subjects With Advanced Selected Solid Tumors treatment 1 / 2 active_not_recruiting NCT04093115
Study of CX1106 in Patients With Advanced Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 withdrawn NCT02734537
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery treatment 2 recruiting NCT01515137
Study of TARCEVA (Erlotinib) as Adjuvant Treatment for Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 1 completed NCT02915432
The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC treatment 1 / 2 unknown_status NCT05222932
Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1 treatment 1 recruiting NCT02661152
DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC. other 3 unknown_status NCT06273852
A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors No drug interventions basic_science 0 recruiting NCT05099952
Sleep and Circadian Rhythm Study in Head and Neck Cancer Patients No drug interventions supportive_care Not Available withdrawn NCT01697800
A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract treatment 2 completed NCT02949700
Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma treatment 1 / 2 completed NCT03319459
FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors treatment 1 completed NCT02279459
Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas No drug interventions Not Available Not Available completed NCT02794675
Intraoperative Placement of Cesium-131 Permanent Interstitial Brachytherapy in Head and Neck Cancer treatment 0 completed NCT05202275
The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs treatment 2 unknown_status NCT06023875
Neoadjuvant Cadonilimab in Combination With Cisplatin and Nab-paclitaxel in Resectable Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT02524275
Docetaxel and Capecitabine With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 2 terminated NCT05412875
Pilot Trial of E Cigarettes in Pts Diagnosed With Cancer of the Head, Neck, and Lung supportive_care Not Available withdrawn NCT05726370
Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC treatment 2 recruiting NCT01581970
Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer treatment 2 completed NCT03195699
Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers treatment 1 active_not_recruiting NCT04854499
Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05540899
Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer No drug interventions treatment 1 recruiting NCT03281499
Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer No drug interventions treatment Not Available completed NCT01425736
Nimotuzumab in Combination With TPF(Cisplatin ,Fluorouracil and Docetaxel) for Head and Neck Squamous Cell Carcinoma treatment 2 completed NCT05289336
DAHANCA 27 Transoral Laser Microsurgery for T1a Glottic Cancer No drug interventions treatment 2 unknown_status NCT04624113
Tazemetostat and Pembrolizumab in Patients With Pembrolizumab- or Nivolumab-Resistant, Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma treatment 1 terminated NCT00894413
A Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract treatment 2 completed NCT06016413
Adelbelimab Combination Chemotherapy in Neoadjuvant Therapy for Squamous Cell Carcinoma of the Head and Neck treatment 2 not_yet_recruiting NCT04234113
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors treatment 1 active_not_recruiting NCT01280318
Profile of Plasma Growth Factors Before and After Head and Neck Oncological or Non-oncological Surgery No drug interventions treatment 1 / 2 completed NCT03552718
QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers. No drug interventions treatment 1 active_not_recruiting NCT03874741
SCT200 Plus Platinum-based Chemotherapy in Head and Neck Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT05044117
Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN) treatment 3 recruiting NCT05565417
Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas treatment 1 / 2 recruiting NCT05585034
Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors treatment 1 recruiting NCT06163534
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC) No drug interventions Not Available Not Available recruiting NCT04651634
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients No drug interventions supportive_care 2 recruiting NCT03082534
Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05918224
Streptococcus Salivarius K12 for Prevention and Treatment of Oral Mucositis in Patients Undergoing Radiotherapy prevention 2 completed NCT03809624
Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer treatment 1 active_not_recruiting NCT05526924
Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer treatment 1 recruiting NCT05433116
Pembrolizumab and Lenvatinib After Definitive Chemoradiation of Locally Advanced HNSCC treatment 2 recruiting NCT03957096
A Safety Study of SGN-CD47M in Patients With Solid Tumors No drug interventions treatment 1 terminated NCT04616196
Study of NKTR 255 in Combination With Cetuximab in Solid Tumors treatment 1 / 2 completed NCT02567396
Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction treatment 1 withdrawn NCT03998696
An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer. treatment 4 completed NCT04740996
Study of Pembrolizumab in the First Line Therapy for R/M HNSCC in China Not Available Not Available unknown_status NCT04987996
GR-MD-02 + Pembrolizumab Versus Pembrolizumab Monotherapy in Melanoma and Squamous Cell Head and Neck Cancer Patients treatment 2 withdrawn NCT04045496
A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors No drug interventions treatment 1 unknown_status NCT05272696
Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC treatment 2 recruiting NCT02639858
Study to Evaluate the Efficacy and Safety of Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC treatment 2 unknown_status NCT03720158
Enteral Omega 3 During Radiotherapy to Improve the Quality of Life and Functionality of Head and Neck Cancer Patients No drug interventions supportive_care Not Available terminated NCT03412058
Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists No drug interventions other Not Available active_not_recruiting NCT06357858
ASTX727 and Nivolumab in Squamous Cell Carcinoma of the Head and Neck treatment 1 withdrawn NCT05322135
A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma diagnostic 0 active_not_recruiting NCT05296135
Predicting Immunotherapy Efficacy in Head and Neck Squamous Cell Cancer No drug interventions Not Available Not Available recruiting NCT05787535
HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor treatment 1 recruiting NCT02024035
Protocole Advanced RadioTherapy ORL No drug interventions Not Available Not Available completed NCT03236935
Phase Ib of L-NMMA and Pembrolizumab treatment 1 active_not_recruiting NCT05065086
Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence No drug interventions Not Available Not Available unknown_status NCT04121286
A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China No drug interventions treatment 1 recruiting NCT05054439
A Clinical Study of SI-B001 in Combination With Paclitaxel in the Treatment of Recurrent and Metastatic HNSCC treatment 2 recruiting NCT05400239
SOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome No drug interventions Not Available Not Available recruiting NCT02004639
Trismus Prevention, Diagnosis and Management: Radiotherapy Planning, Early Detection, and Physical Therapy Intervention No drug interventions prevention Not Available unknown_status NCT06575322
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma Not Available Not Available recruiting NCT05075122
Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With Pembrolizumab treatment 2 recruiting NCT02143622
Study of Efficacy and Safety of LJM716 and Cetuximab in Head and Neck Squamous Cell Carcinoma Patients treatment 1 / 2 withdrawn NCT04762225
RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma No drug interventions treatment 1 terminated NCT05747625
(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma diagnostic 1 recruiting NCT04634825
Enoblituzumab Plus Retifanlimab or Tebotelimab in Head and Neck Cancer treatment 2 terminated NCT05343325
The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC treatment 2 recruiting NCT02345330
Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC) treatment 2 terminated NCT05220748
RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCC treatment 1 withdrawn NCT06338657
FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer treatment 1 recruiting NCT03212157
GlucoCEST MRI in Oncology No drug interventions basic_science Not Available completed NCT05280457
HPV 16-positive and/or HPV 18-positive Recurrent and/or For Patients With Metastatic Head and Neck Cancer to Evaluate GX-188E DNA Vaccination, GX-I7 and Nivolumab Combination Therapy treatment 2 recruiting NCT04442126
A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors No drug interventions treatment 1 / 2 terminated NCT03524326
Testing Lenvatinib and Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma and Cutaneous Squamous Cell Carcinoma treatment 1 completed NCT03070366
Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC No drug interventions treatment 2 active_not_recruiting NCT04525066
Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma treatment 2 completed NCT05859074
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer treatment 1 active_not_recruiting NCT05576974
A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY) diagnostic 2 recruiting NCT06525220
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer treatment 3 recruiting NCT03666273
Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1. treatment 1 completed NCT03916627
Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients treatment 2 recruiting NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors treatment 2 recruiting NCT03953976
INRT-AIR: A Prospective Phase II Study of Involved Nodal Radiation Therapy No drug interventions treatment 2 completed NCT05286060
Trial of the Combination of GX-188E Vaccination, GX-I7 and Pembrolizumab in Patients With Advanced, Resectable HPV Type 16 and/or 18 Positive Head and Neck Cancer treatment 2 recruiting NCT05286294
Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders treatment 2 recruiting NCT04675294
Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03) treatment 2 active_not_recruiting NCT03383094
Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer treatment 2 recruiting NCT05047094
A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC treatment Not Available recruiting NCT05351762
Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC treatment 2 unknown_status NCT05437380
Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC No drug interventions diagnostic Not Available recruiting NCT03942380
Cell-free Tumor DNA in Head and Neck Cancer Patients No drug interventions diagnostic Not Available recruiting NCT03735680
A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer diagnostic 2 completed NCT01950689
NIMRAD (A Randomised Placebo-controlled Trial of Synchronous NIMorazole Versus RADiotherapy Alone in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Not Suitable for Synchronous Chemotherapy or Cetuximab) treatment 3 completed NCT02126189
The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute Head and Neck Cancer Study No drug interventions Not Available Not Available unknown_status NCT05516589
Neoadjuvant Chemotherapy, Tislelizumab With Afatinib for HNSCC treatment 2 recruiting NCT04564989
Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC No drug interventions Not Available Not Available recruiting NCT06332092
FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT03655444
Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy treatment 1 / 2 terminated NCT03435640
REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies treatment 1 / 2 terminated NCT06082167
Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma treatment 2 / 3 recruiting NCT04074967
Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab treatment 1 / 2 active_not_recruiting NCT05446467
Pembrolizumab in Combination With Low-dose PFas Neoadjuvant Treatment for Locally Advanced HNSCC treatment 2 recruiting NCT05229601
A Study of HFB301001 in Adult Patients With Advanced Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT04213404
Ribociclib and Spartalizumab in R/M HNSCC treatment 1 active_not_recruiting NCT04032704
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors treatment 2 terminated NCT05538572
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors No drug interventions treatment 1 completed NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors diagnostic 2 recruiting NCT04946968
Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers treatment 2 recruiting NCT06183268
Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy No drug interventions supportive_care Not Available recruiting NCT05136768
Sintilimab Combined With Chemotherapy and SBRT in Limited Metastatic Head and Neck Squamous Cell Carcinoma (LM-HNSCC) treatment 2 not_yet_recruiting NCT03212469
A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer treatment 1 / 2 active_not_recruiting NCT01172769
Efficacy Study of Temsirolimus to Treat Head and Neck Cancer treatment 2 completed NCT06006169
A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (Non-nasopharyngeal Carcinoma) and Other Solid Tumors No drug interventions treatment 2 recruiting NCT01807546
Oral Rigosertib for Squamous Cell Carcinoma treatment 2 completed NCT01469546
Phase II Trial Evaluating Axitinib In Patients With Unresectable, Recurrent Or Metastatic Head And Neck Cancer treatment 2 completed NCT05784012
Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma treatment 1 / 2 recruiting NCT03247712
Neoadjuvant Immunoradiotherapy in Head & Neck Cancer treatment 1 / 2 active_not_recruiting NCT05217212
Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer? No drug interventions Not Available Not Available recruiting NCT00805012
Docetaxel and S-1 in Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 2 terminated NCT03421912
Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR) No drug interventions supportive_care Not Available completed NCT05031910
Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality No drug interventions treatment Not Available recruiting NCT02538510
Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery treatment 1 / 2 completed NCT03476681
Study of NEO-201 in Solid Tumors Expansion Cohorts treatment 1 / 2 recruiting NCT04297995
Evaluate the Efficacy and Safety of HLX10 in Combination With HLX07 in Patients With Advanced Head and Neck Tumors treatment 2 active_not_recruiting NCT06413095
PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS basic_science 0 completed NCT06102395
Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC treatment 3 recruiting NCT02268695
Platinum-Cetuximab Combined With Docetaxel or With 5FU in Patients With Recurrent/Metastatic HNSCC treatment 2 completed NCT06087614
Dose Escalation Using Hypoxia-adjusted Radiotherapy treatment 2 recruiting NCT04452214
A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors treatment 1 completed NCT01864850
Non Inferiority Trial of Standard RT Versus Hypofractionated Split Course in Elderly Vulnerable Patients With HNSCC No drug interventions other 3 completed NCT04831450
Phase 2 Trial of Maintenance Cemiplimab for Head and Neck Squamous Cell Carcinoma (HNSCC) treatment 2 withdrawn NCT01824823
Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of Recurrence treatment 2 terminated NCT04253808
Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes No drug interventions supportive_care Not Available completed NCT03340038
Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps No drug interventions health_services_research Not Available completed NCT04096638
Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors treatment 1 active_not_recruiting NCT03953443
Expression & Epigenetic Silencing of MicroRNA for Predicting Therapeutic Response and Prognosis of HPV-negative HNSCC No drug interventions Not Available Not Available active_not_recruiting NCT06494943
Induction IBI110 and Sintilimab With Chemotherapy In LA HNSCC treatment 1 active_not_recruiting NCT06540443
Pilot Study of MPB-2043 Enhanced MRI for Nodal Staging in Head and Neck Squamous Cell Carcinomas No drug interventions diagnostic 1 not_yet_recruiting NCT05581004
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT05768139
First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors treatment 1 / 2 recruiting NCT05814666
Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC treatment 2 recruiting NCT06259552
A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors No drug interventions treatment 1 recruiting NCT03719690
Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy treatment 2 completed NCT05980702
4 Courses vs 2 Courses of Pembrolizumab Combined With Carboplatin and Albumin-binding Paclitaxel of Neoadjuvant Therapy in HNSCC treatment 2 recruiting NCT00609284
Randomized Trial of Concomitant Chemotherapy in Patients With Locally Advanced HNSCC Treated by Radiotherapy-erbitux treatment 3 completed NCT04370587
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors treatment 1 / 2 recruiting NCT04272333
Intratumoral Microdosing of Motolimod in HNSCC basic_science 0 terminated NCT04279509
Selecting Chemotherapy With High-throughput Drug Screen Assay Using Patient Derived Organoids in Patients With Refractory Solid Tumours (SCORE) No drug interventions diagnostic Not Available unknown_status NCT04157985
Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors treatment 3 recruiting NCT05980000
Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma treatment 2 recruiting NCT03740100
Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations treatment 2 terminated NCT06190275
Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma No drug interventions treatment Not Available recruiting NCT06446570
Phase II Study of Durvalumab(MEDI4736) + Tremelimumab in Pulmonary Sarcomatoid Carcinoma treatment 2 completed NCT06366906
10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma No drug interventions Not Available Not Available completed NCT04141449
A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation No drug interventions health_services_research 2 recruiting NCT03422536
Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma treatment 2 completed NCT05831917
MRI - Guided Adaptive RadioTHerapy for Dysphagia in Head and Neck Cancer No drug interventions treatment Not Available recruiting NCT04340258
Trial Combining Pembrolizumab and Cesium 131 Brachytherapy With Salvage Surgery in HNSCC treatment 1 / 2 active_not_recruiting NCT04042935
Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC supportive_care 1 completed NCT02433626
Study of COTI-2 as Monotherapy or Combination Therapy for the Treatment of Malignancies treatment 1 unknown_status NCT04169074
Immune Modulation by Abemaciclib in HNSCC. (AIM Trial) treatment 2 recruiting NCT05902520
Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors No drug interventions treatment 1 recruiting NCT03107182
Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer treatment 2 active_not_recruiting NCT05337631
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy No drug interventions Not Available Not Available recruiting NCT03367780
Dose-Effect Relation of Salivary Gland Irradiation No drug interventions Not Available Not Available completed NCT05602792
A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors treatment 1 / 2 recruiting NCT03480672
Postoperative aRCH With Cisplatin Versus aRCH With Cisplatin and Pembrolizumab in Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT04354246
COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies treatment 1 recruiting NCT05192655
Artificial Intelligence in Functional Imaging for Individualized Treatment of Head and Neck Squamous Cell Carcinoma Patients No drug interventions Not Available Not Available recruiting NCT03292250
Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)] prevention 2 completed NCT04997902
Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) treatment 1 / 2 recruiting NCT03356587
A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy prevention 2 unknown_status NCT02999087
Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH) treatment 3 active_not_recruiting NCT02998385
Chemo-radiotherapy Versus Radiotherapy in the Treatment of Salivary Glands and Nasal Tumors (IMRT or Protontherapy) treatment 3 recruiting NCT05980715
PD-1 Inhibitor Therapy Versus Radiotherapy in pCR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy No drug interventions treatment 3 recruiting NCT03917537
WGA in Platinum-refractory HNSCC Underwent Nivolumab No drug interventions Not Available Not Available unknown_status NCT03726775
Trial Evaluating the Tolerance and Safety of Durvalumab - RT Combination for Treatment in SCCHN treatment 2 active_not_recruiting NCT03652142
Predictive Biomarkers for Response to Nivolumab in Head and Neck Squamous Cell Carcinoma Not Available Not Available unknown_status NCT06016699
Immunological Function After Radiation With Either Proton or Photon Therapy No drug interventions Not Available Not Available recruiting NCT04892849
Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy No drug interventions Not Available Not Available recruiting NCT04114136
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies treatment 2 recruiting NCT06090318
Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss treatment 1 / 2 withdrawn NCT02216617
Evaluation of the Tolerance of Afatinib in Combination With Docetaxel and Cisplatin in LAHNSCC Induction Chemotherapy treatment 1 completed NCT02216916
Phase II Trial of HM781-36B in Patients With Metastatic/Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) After Failure of or Unfit for Platinum-containing Therapy treatment 2 unknown_status NCT06107686
A Study of YL202 in Selected Patients With Advanced Solid Tumors No drug interventions treatment 2 active_not_recruiting NCT05877430
Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer treatment 1 / 2 recruiting NCT05831930
The Effect of Nitozumab in the Treatment of Head and Neck Squamous Cell Carcinoma No drug interventions treatment 0 recruiting NCT06016920
Safety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma treatment 1 / 2 recruiting NCT04811027
Combination Study With Eftilagimod Alpha (a Soluble LAG-3 Fusion Protein) and Pembrolizumab in Patients With Recurrent or Metastatic HNSCC treatment 2 active_not_recruiting NCT04606940
Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN) No drug interventions Not Available Not Available completed NCT04861467
Camrelizumab as a Maintenance Therapy After Chemoradiation in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT03625323
Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC treatment 2 active_not_recruiting NCT02069158
Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid Tumor treatment 1 completed NCT00002774
Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer treatment 2 completed NCT01783158
Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma No drug interventions Not Available Not Available completed NCT04597476
A Randomized, Double-blind Study to Evaluate the Clinical Effect and Safety of Fucoidan in Patients With Squamous Cell Carcinomas of the Head and Neck No drug interventions supportive_care 2 recruiting NCT01166542
Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers treatment 3 completed NCT00753038
Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Head and Neck Carcinoma treatment 2 completed NCT01268878
Hematologic Toxicity Observation of the Docetaxel+ Cisplatin+ Fluorouracil (TPF)Medical Protocol No drug interventions Not Available Not Available completed NCT00408252
Efficacy of SU 011248 in Head And Neck Carcinoma treatment 2 terminated NCT01233843
Chemoradiotherapy HNSCC, Randomized Study, Docetaxel,Cisplatin, 5FU,Erbitux. treatment 3 completed NCT03673735
Maintenance Immune Check-point Inhibitor Following Post-operative Chemo-radiation in Subjects With HPV-negative HNSCC treatment 3 withdrawn NCT01289522
Chemotherapy With Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer treatment 2 completed NCT06003231
A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2 treatment 2 recruiting NCT02277184
Ficlatuzumab, Cisplatin and IMRT in Locally Advanced Head and Neck Squamous Cell Carcinoma other 1 terminated NCT01876693
A Prospective Study of Prophylactic Gastrostomy in Head and Neck Cancer Patients Undergoing Chemoradiotherapy No drug interventions treatment Not Available terminated NCT02113878
Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck treatment 1 completed NCT03485209
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors treatment 2 recruiting NCT05845632
Time to Treatment and Disease-free Survival of Patients With High-risk Head-neck Cutaneous Squamous Cell Carcinoma No drug interventions Not Available Not Available active_not_recruiting NCT03088059
Biomarker-based Study in R/M SCCHN treatment 2 active_not_recruiting NCT01417936
Sym004 in SCCHN Patients Failing Anti-EGFR Based Therapy treatment 2 completed NCT00982696
Treatment of Advanced Head and Neck Cancer No drug interventions treatment 2 terminated NCT00957086
Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer treatment 3 active_not_recruiting NCT01080066
A Post Marketing Surveillance Study of Cetuximab in Patients With Squamous Cell Carcinoma of Head and Neck (SCCHN) No drug interventions Not Available Not Available completed NCT02383966
Phase III Trial to Assess Efficacy and Safety of Cetuximab for the Treatment of Chinese Participants With Head and Neck Cancer treatment 3 completed NCT01415674
Research of Biomarkers of Activity and Efficacy of BIBW2992 in Untreated Non-metastatic HNSCC Patients treatment 2 completed NCT02585973
Dose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC treatment 1 completed NCT02938273
Bioimmunoradiotherapy (Cetuximab/RT/Avelumab) treatment 1 completed NCT00412776
Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer treatment 2 / 3 terminated NCT02052960
CetuGEX™ in Comparison to Cetuximab for the Treatment of Patients With Head and Neck Cancer treatment 2 completed NCT01836029
Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT02952989
A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors treatment 1 terminated NCT03799744
Safety,Tolerability,and Efficacy of VCN-01 With Durvalumab in R/M Head and Neck Squamous Cell Carcinoma treatment 1 unknown_status NCT02753140
Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy treatment 2 unknown_status NCT02655068
Phase III Trial of PET/CT vs. CTSurveilance for Head and Neck Cancer No drug interventions diagnostic 3 terminated NCT02658214
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors treatment 1 completed NCT01115790
A Phase 1 Study in Participants With Advanced Cancer treatment 1 completed NCT03735290
A Study to Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer treatment 1 terminated NCT03291002
Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC treatment 1 unknown_status NCT02289209
Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck treatment 2 active_not_recruiting NCT03788785
Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer No drug interventions supportive_care Not Available completed NCT02101034
PD 0332991 and Cetuximab in Patients With Incurable SCCHN treatment 1 / 2 completed NCT02242916
State of the Art Photon Therapy Versus Particle Therapy for Recurrent Head & Neck Tumors; a Planning Study No drug interventions Not Available Not Available completed NCT03109158
NC-6004 With 5-FU and Cetuximab for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treatment 1 / 2 completed NCT03540563
ctDNA as a Biomarker for Treatment Response in HNSCC No drug interventions diagnostic Not Available completed NCT01606566
A Study to Evaluate the Safety and Efficacy of Amphinex Induced PCI of Bleomycin for Recurrent Head and Neck Cancer. treatment 2 terminated NCT02822482
Copanlisib in Association With Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinomas Harboring a PI3KCA Mutation/Amplification and/or a PTEN Loss treatment 1 / 2 terminated NCT01588431
Bevacizumab/Ph 2 for Locally Advanced Head and Neck Cancer treatment 2 completed NCT01307267
A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab treatment 1 completed NCT03715946
Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer treatment 2 active_not_recruiting NCT03509012
Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors treatment 1 active_not_recruiting NCT01538381
Neoadjuvant Afatinib Window Study in Squamous Cell Carcinoma of the Head and Neck treatment 2 completed NCT02438995
Super-Selective Intraarterial Infusion of Cetuximab (Erbitux) With or Without Radiation Therapy for the Treatment of Unresectable Recurrent Squamous Cell Carcinoma of the Head and Neck treatment 1 terminated NCT03620123
A Randomized Phase II Study on the Optimization of Immunotherapy in Squamous Carcinoma of the Head and Neck treatment 2 completed NCT05724329
Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01) treatment 2 active_not_recruiting NCT06297811
Myeloprotection With Trilaciclib in Pan-cancer Population prevention 2 not_yet_recruiting NCT06235918
Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma treatment 2 recruiting NCT04992559
A Study of Toripalimab as Consolidation Therapy After Postoperative Chemoradiotherapy in HNSCC treatment 2 recruiting NCT05233436
PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors treatment 1 terminated NCT05582265
Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I) treatment 3 recruiting NCT06469008
A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors No drug interventions treatment 1 recruiting NCT05070247
A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors treatment 1 / 2 recruiting NCT04844073
A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer No drug interventions treatment 1 / 2 recruiting