NCT05216328
Prevention of Opioid-induced Constipation in Patients With Advanced Cancer prevention 4 recruiting NCT01901302
Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation treatment 3 terminated NCT01696643
Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation treatment 3 terminated NCT04404933
Study of Opioid-Induced Constipation 2 Project No drug interventions Not Available Not Available completed NCT03720613
Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain Not Available Not Available recruiting NCT01645371
Assessing a Stool Symptom Screener in Patients With Chronic Opioid-Induced Constipation No drug interventions Not Available Not Available completed NCT01382797
ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC) treatment 2 completed NCT01186770
A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain treatment 3 completed NCT00858754
Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects treatment 4 withdrawn NCT00672477
Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness treatment 4 completed NCT01117051
Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation treatment 3 terminated NCT01623609
Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol basic_science 1 completed NCT02813356
Naloxegol US PMR CV Safety. Not Available Not Available active_not_recruiting NCT05149833
European Study of Opioid Induced Constipation No drug interventions Not Available Not Available recruiting NCT03687268
Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation treatment 3 unknown_status NCT05133076
Safety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based Medications treatment 2 recruiting NCT04350112
Study of Opioid-Induced Constipation 1 Project No drug interventions Not Available Not Available completed NCT02270983
Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain treatment 2 completed NCT01965652
Long Term Safety of Naldemedine treatment 3 completed NCT01901328
Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation treatment 3 terminated NCT01443403
A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy treatment 2 completed NCT01100151
ALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC) treatment 2 completed NCT01050595
Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit treatment 3 unknown_status NCT01040637
A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation treatment 1 / 2 completed NCT00399659
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain. treatment 3 terminated NCT01207427
Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain treatment 2 completed NCT02813369
Naloxegol Health Outcome Post Authorisation Safety Study Not Available Not Available terminated NCT01957046
A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC). No drug interventions treatment 4 completed NCT03060512
To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation treatment 4 completed NCT01812733
Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives No drug interventions Not Available Not Available completed NCT01109511
A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy prevention 4 completed NCT01401985
A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC) treatment 2 completed NCT05770960
Colonic Motor Patterns in Healthy Volunteers treatment 4 completed NCT04173858
Evaluation of the Quality of Life of Patients With Opioid-induced Constipation Under Treatment With Naloxegol Not Available Not Available completed NCT02574819
Study of Methylnaltrexone in Opioid-Induced Constipation Patients treatment 2 / 3 unknown_status NCT01993940
Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation treatment 3 completed NCT01965158
Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation treatment 3 completed NCT01901341
The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation treatment 3 terminated NCT01368562
Compassionate Use Study of Methylnaltrexone treatment Not Available completed NCT01384292
Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain treatment 3 terminated NCT00672139
Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness treatment 4 completed NCT00640146
Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures treatment 2 completed NCT00414024
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain. treatment 3 terminated NCT00984334
Naloxone SR Capsules in Patients With Opioid Induced Constipation treatment 2 completed NCT02813148
Naloxegol Drug Utilization Post Authorisation Safety Study Not Available Not Available completed NCT01459926
A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation treatment 2 completed NCT03638440
Real World Observational Study of Naloxegol for Patients With Cancer Pain Diagnosed With OIC. Not Available Not Available completed NCT01309841
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation treatment 3 completed NCT00600119
A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC) treatment 2 completed NCT05588323
Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids supportive_care 1 / 2 recruiting NCT01336205
Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation treatment 3 completed NCT01323790
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation treatment 3 completed NCT01395524
A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation treatment 3 completed NCT01333540
A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation treatment 2 completed