Weight Reduction (DBCOND0043475)
Identifiers
- Synonyms
- Reduction, Weight / Lost weight / Loss of weight / Wt loss / Losing wt / Weight loss finding (finding) / Weight loss / Weight decreasing (finding) / Weight decreased (finding)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Orlistat A reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.- Pancreatic triacylglycerol lipasetarget
- Fatty acid synthasetarget
- Gastric triacylglycerol lipasetarget
- Cytochrome P450 3A4enzyme
- Cytosolic phospholipase A2enzyme
- Albumincarrier
- Fatty acid synthaseenzyme
- Cannabinoid receptor 1target
Topiramate An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.- Gamma-aminobutyric acid receptor subunit alpha-1target
- Voltage-gated sodium channel alpha subunittarget
- Carbonic anhydrase 2target
- Carbonic anhydrase 4target
- Kainate receptorstarget
- Cytochrome P450 2C19enzyme
- Cytochrome P450 3A4enzyme
- Carbonic anhydrase 1target
- Carbonic anhydrase 3target
- Voltage gated L-type calcium channeltarget
- Voltage-dependent R-type calcium channeltarget
- Albumincarrier
- ATP-dependent translocase ABCB1transporter
- 5'-AMP-activated protein kinasetransporter
- Glutamate receptor ionotropic, kainate 1target
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT05412797 Use of a DeskCycle to Reduce Sedentary Behavior During the Workday No drug interventions prevention Not Available completed NCT02749305 Comparative Effectiveness of Bariatric Surgery With PROMs No drug interventions supportive_care Not Available unknown_status NCT02364128 Improving Patient Decisions About Bariatric Surgery No drug interventions other 2 completed NCT04392752 Fitness Study 2020 No drug interventions basic_science Not Available unknown_status NCT02620059 A Lifestyle Program on Healthy Weight in Postpartum Period No drug interventions prevention Not Available completed NCT05921565 M-POWER Feasibility Study No drug interventions treatment Not Available completed NCT00877240 The Influence of an Intervention Program on Altering Health Behavioral Patterns Among IDF's Staff No drug interventions Not Available Not Available withdrawn NCT01030354 Effects of Protein-Enriched Meal on Liver, Kidney or Bone: a Randomized Controlled Trial No drug interventions treatment 2 / 3 completed NCT04149756 Persistent Weight Maintenance for 6 Months After 3 Months of Active Weight Loss No drug interventions Not Available Not Available unknown_status NCT02769585 Efficacy of Self-hypnosis for Weight Loss in Type 2 Diabetics No drug interventions treatment Not Available completed NCT03534336 Behavioral Economics-Based Online Lifestyle Balance Program No drug interventions treatment Not Available completed NCT06553963 Athlete Biochemical Monitoring and Nutritional Support No drug interventions prevention Not Available not_yet_recruiting NCT04910620 The Evaluation of TCI378 and TCI507 Probiotics on Weight-lowering Efficacy in Adults No drug interventions treatment 4 unknown_status NCT01923350 Avoiding Diabetes After Pregnancy Trial No drug interventions prevention Not Available completed NCT05981508 Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program No drug interventions treatment Not Available recruiting NCT05059938 MyFitnessPal Pilot Study No drug interventions treatment Not Available withdrawn NCT02227043 Study Of Weight Development Over Time No drug interventions Not Available Not Available completed