Diabetic Peripheral Neuropathy (DPN) (DBCOND0049986)

Identifiers

Synonyms
Diabetic Neuropathy Peripheral / Peripheral Diabetic Neuropathy / Diabetic Peripheral Neuropathy / Peripheral neuropathy due to diabetes mellitus (disorder) / Diabetic neuropathy / Diabetic Neuropathies / Neuropathy due to diabetes mellitus (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Capsaicin
A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Mepivacaine
A local anesthetic used for local or regional analgesia or anesthesia.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03440203
Prevalence of Peripheral Neuropathy and Its Impact on Activities of Daily Living in Patients With Type 2 DiabetesNo drug interventionsNot AvailableNot Availablecompleted
NCT03847779
Microcirculatory Vasomotor Changes in Type 2 Diabetes With Peripheral NeuropathyNo drug interventionsdiagnosticNot Availablecompleted
NCT03685253
Nicotinamide Riboside for Diabetic Neuropathytreatment1 / 2suspended
NCT06201611
Evaluating a Nitric Oxide Generator, Nebivolol as a Disease Modifier in Patients With Diabetic Neuropathy.treatment2 / 3not_yet_recruiting
NCT05558878
Effect of Ambroxol in Diabetic Peripheral NeuropathytreatmentNot Availableunknown_status
NCT03354806
Peripheral Analgesia in Painful Diabetic NeuropathyNo drug interventionssupportive_careNot Availablewithdrawn
NCT03988413
Study on Safety, Absorption and Metabolism of SYHA1402 Tablets in Healthy PeopleNo drug interventionstreatment1completed
NCT05299918
Diabetic Neuropathy Rapid Screening Test in Turkish Patients With Type 2 Diabetes: SudoscanNo drug interventionsNot AvailableNot Availablecompleted
NCT03725917
Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot UlcersNo drug interventionspreventionNot Availableunknown_status
NCT04841720
A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tabletstreatment1unknown_status
NCT04253860
Effect of Transcutaneous Electrical Nerve Stimulation in Diabetic NeuropathyNo drug interventionstreatment3terminated
NCT03888872
Effect of High Tone Power Therapy on Neurophysiological Measures and Function Outcome in Patients With Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT03676595
Video Game Balance Training for Patients With Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT03455543
Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT05642143
Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic NeuropathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05921097
Comparison of Histamine and Local Heating for Evoking the Axon-reflex Flare Response in DiabetesNo drug interventionsNot AvailableNot Availablecompleted
NCT06463015
Posterior Tibial Nerve PRF for Diabetic Neuropathic PainNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05977465
Empagliflozin in Treatment of Peripheral Diabetic Neuropathytreatment1 / 2completed
NCT05461274
Determining Patterns In Trial Experiences of Diabetic Neuropathy PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03907189
Ambulation as a Factor on Oscillating ThermometryNo drug interventionsNot AvailableNot Availableunknown_status
NCT06131918
Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathytreatment2completed
NCT03113448
0.075% Capsaicin Lotion for the Treatment of Painful Diabetic Neuropathytreatment3completed
NCT06066944
Effects of Self-Thai Foot Massage on Pain, Range of Motion and Functional Disability in Type 2 DMNo drug interventionsotherNot Availablenot_yet_recruiting
NCT05491850
Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical TrialNo drug interventionstreatmentNot Availablecompleted
NCT01293461
Safety and Pharmacokinetics of CBX129801 in Patients With Type 1 Diabetestreatment1 / 2completed
NCT04561609
Transcutaneous Application of Gaseous CO2No drug interventionstreatmentNot Availableunknown_status
NCT06495424
Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral NeuropathyNot AvailableNot Availablenot_yet_recruiting
NCT01247558
Administrative Claims Analysis of Metanx® in Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT04832464
BRACE(Balance, Resistance, Aerobic and Cognitive Exercise) Protocol for Diabetic).Peripheral Neuropathic Patients.No drug interventionstreatmentNot Availableunknown_status
NCT03865953
Oral LAT8881 in Neuropathic PainNo drug interventionstreatment2completed
NCT05319275
Study of Acetyllevocarnitine Hydrochloride Tablets in Chinese Patients With Paresthesias Caused by DPNNo drug interventionstreatment3completed
NCT05965336
Walking Function in Diabetic Peripheral NeuropathyNo drug interventionsbasic_scienceNot Availablerecruiting
NCT06074562
A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic PainNo drug interventionstreatment2recruiting
NCT06519942
Muscle and Bone in Patients with Diabetes Mellitus and NeuropathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06591780
Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral NeuropathyNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT05162690
Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathytreatment2 / 3unknown_status
NCT02927951
The Effect of Pregabalin on Pain Related to Walking in Patients With Diabetic Peripheral Neuropathytreatment3completed
NCT06303453
Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy.No drug interventionstreatmentNot Availablerecruiting
NCT00933998
Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®No drug interventionstreatmentNot Availablecompleted
NCT00623961
Validation Study of Neuropathic PainNo drug interventionsNot AvailableNot Availablecompleted
NCT02947828
Polyneuropathy in Diabetes Mellitus Type 2No drug interventionsNot AvailableNot Availablecompleted
NCT03077893
Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT04658693
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral NeuropathyNo drug interventionsdevice_feasibilityNot Availablerecruiting
NCT04688671
Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic PainNo drug interventionstreatment2completed
NCT03767478
Neuromuscular Electrical Stimulation For The Treatment of Diabetic NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT05521737
Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT00861952
Neuragen for Peripheral Diabetic NeuropathyNo drug interventionstreatment3withdrawn
NCT03983200
Effect of Rotating Magnetic Therapy on Diabetic Peripheral NeuropathytreatmentNot Availableunknown_status
NCT03450200
Effectiveness of Exercises in Patient With Diabetic Peripheral NeuropathyNo drug interventionssupportive_careNot Availablecompleted
NCT01469559
Safety Study of Intranasal Insulin in Type 1 Diabetes and Diabetic Peripheral Neuropathyprevention2completed
NCT06287736
Spinal Cord Stimulation and Small Fiber Peripheral NeuropathyNo drug interventionsotherNot Availablerecruiting
NCT04453618
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of SYHA1402 in Healthy SubjectsNo drug interventionstreatment1unknown_status
NCT03356041
The Role of a Clinical Pharmacist in Lifestyle Modification in Type 2 Diabetic Patients With Peripheral NeuropathyNo drug interventionssupportive_careNot Availableunknown_status
NCT06130917
Effects of Multisystem Exercise on Balance, Postural Stability, Mobility and Pain in Patients With DPN.No drug interventionstreatmentNot Availablecompleted
NCT05565924
Alter-G Training on Gait and Balance in Diabetic Neuropathy PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00855439
Evaluation of Exenatide in Patients With Diabetic NeuropathytreatmentNot Availablecompleted
NCT04440839
Implementation of Telemedicine for Patient With Lower Extremity WoundsNo drug interventionstreatmentNot Availablecompleted
NCT04543422
Green Tea Extracts for Mild-to-moderate Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT01893125
Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Diabetic Peripheral Neuropathytreatment2completed
NCT02461225
Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot PainNo drug interventionstreatmentNot Availablecompleted
NCT01512030
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02104466
Group Acupuncture Treatment Effects for Painful Diabetic Neuropathy (GATE-PDN)No drug interventionstreatmentNot Availablecompleted
NCT06483620
Cross-cultural Adaptation and Validity of the Arabic-translated NEUROPATHY-SPECIFIC QUALITY OF LIFE QuestionnaireNo drug interventionsNot AvailableNot Availablerecruiting
NCT05347420
Diagnostic Accuracy of Quantitative Neuropad Test for Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00159731
Safety of Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathytreatment4completed
NCT01040962
Fall Risk Assessment in People With Diabetic NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT05281562
Immunonutrition for Diabetic Foot Ulcerstreatment2 / 3terminated
NCT06479629
The Effect of Piracetam on Diabetic Peripheral Neuropathy Patientstreatment4not_yet_recruiting
NCT01990092
The Nutritional Benefits of Metanx in Patients With Diabetic Peripheral Neuropathy (MEDIAN)No drug interventionssupportive_careNot Availableunknown_status
NCT02039544
A Study of Xuebi Formula for Diabetic Peripheral Neuropathy(Qi-deficiency and Blood-stasis)No drug interventionstreatmentNot Availableunknown_status
NCT01474772
Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN)treatment3completed
NCT06041412
The Effect of Related Blood Markers on Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06191614
DEXINEURO® Tab on Blood Glucose Reduction in Patients With Type 2 Diabetes Accompanied by Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT01086150
Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathytreatment2 / 3completed
NCT06033508
Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients With and Without PolyneuropathyNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05660538
Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)treatment2completed
NCT01087203
A Study Of The Analgesic (Pain-Relief) Effects Of Tanezumab In Adult Patients With Diabetic Peripheral Neuropathytreatment2terminated
NCT03250403
Efficacy of Platelet Rich Plasma Injection in Diabetic NeuropathytreatmentNot Availablecompleted
NCT01735903
Objective Measures of Nerve Integrity, Posture, Gait and Blood Flow, After Nerve DecompressionNo drug interventionsNot AvailableNot Availablerecruiting
NCT01681290
Safety and Efficacy of CBX129801 in Patients With Type 1 Diabetestreatment2completed
NCT02728687
Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathytreatment1 / 2completed
NCT06330233
Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04455633
Efficacy, Safety, and PK of LX9211 in Patients With Diabetic Peripheral Neuropathic PainNo drug interventionstreatment2completed
NCT00476151
A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathytreatment2completed
NCT00641953
IMX-150 Cream for Diabetic Neuropathytreatment2completed
NCT06048653
Effect of Non-invasive Vagus Nerve Stimulation on Cognitive Functions in Diabetic Polyneuropathy PatientsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04257877
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)No drug interventionsNot AvailableNot Availablerecruiting
NCT04217005
Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory FeedbackNo drug interventionssupportive_careNot Availablerecruiting
NCT05580705
Effects of Vibration Therapy in Addition to Routine Physical Therapy in Patients With Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT02332005
12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled StudyNo drug interventionstreatment2 / 3completed
NCT00891683
Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral NeuropathyNo drug interventionstreatment2completed
NCT04408261
BuqitongluO Granule for Qi Deficiency and Blood Stasis SyndromeNo drug interventionstreatment2unknown_status
NCT01533428
A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN)treatment3completed
NCT02328911
Laser Therapy for Diabetic Peripheral Neuropathic PainNo drug interventionstreatment2withdrawn
NCT03913793
Aerobic Training in Post-MI Patients With DPNNo drug interventionssupportive_careNot Availablecompleted
NCT05863793
Clinical Study of Acupuncture in the Treatment of Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT05993871
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06400888
Needle-Free Subcutaneous Injector and Conventional Intramuscular Injection of Mecobalamin in Diabetes Peripheral NeuropathyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06397209
Comparative Effects of Propioceptive Neuromascular Facilitation and Neural Flossing in Diabetic NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT03447756
Titration Study of ABX-1431treatment1completed
NCT05613556
Monitoring Physiologic Parameters in Individuals With Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT04638556
Effect of Circulating lncRNAs on Type 2 Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04543032
Sensorimotor Training and Gait in Diabetic PolyneuropathyNo drug interventionstreatmentNot Availablecompleted
NCT03252132
Resistance Training in Patients With Diabetic NeuropathyNo drug interventionsotherNot Availablecompleted
NCT04873232
A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathytreatment3recruiting
NCT04807452
Strength And Balance Training on Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT04605900
Impact of Therapeutic Footwear and Plantar Orthoses on Diabetic Neuropathic Foot in Quality of Life and FunctionalityNo drug interventionssupportive_careNot Availablecompleted
NCT01041859
A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathytreatment3completed
NCT02308059
Ultrasonographic Evaluation of Diabetic NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT01620775
MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic PainNo drug interventionsbasic_scienceNot Availableterminated
NCT03712475
Pharmacokinetics of Two Formulation of Pregabalintreatment4completed
NCT04720170
Exploratory Study of the Efficacy of Standard of Care Revascularization of the Lower ExtremityNo drug interventionstreatmentNot Availableunknown_status
NCT05296642
Exercise Induced Hypoalgesia DiabetesNo drug interventionsdiagnosticNot Availablewithdrawn
NCT06041399
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathyprevention4recruiting
NCT01368549
Metanx® P.L.U.S. Program (Progress Through Learning, Understanding & Support)No drug interventionsNot AvailableNot Availableunknown_status
NCT02387749
Effect Of Mesenchymal Stem Cells Transfusion on the Diabetic Peripheral Neuropathy Patients .No drug interventionstreatmentNot Availablecompleted
NCT06074913
Early Warning of Diabetic Peripheral Neuropathy by Using Infrared Thermography and the Effectiveness of Electroacupuncture in Its PreventionNo drug interventionspreventionNot Availablerecruiting
NCT02337218
Electrical Stimulation for Improving Balance in DiabetesNo drug interventionstreatmentNot Availablecompleted
NCT05921019
Laser Acupuncture on Diabetes-induced Peripheral NeuropathyNo drug interventionstreatmentNot Availablerecruiting
NCT03909841
Neuropathic Pain in Elderly People With Diabetes: Impact on Quality of Life and CognitionNo drug interventionsNot AvailableNot Availablecompleted
NCT00614341
Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label StudyNo drug interventionstreatment4completed
NCT05118217
Microvascular Dysfunction in Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06579716
Whole-Body Vibration Versus Kineso Tape on Nerve Conduction in Patient With Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT05041816
Peripheral Nerve Responses to Focal Vibration and Implications in Pain and Mobility for Patients With Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablewithdrawn
NCT00712439
Safety and Efficacy of Gabapentin in Diabetic Peripheral Neuropathytreatment2completed
NCT00835757
Diffusion Tensor Imaging of Sural Nerves in Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT05389566
Diabetes, Falls, and FracturesNo drug interventionsNot AvailableNot Availablecompleted
NCT01496365
Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathytreatment2completed
NCT06262074
Effect of Structured Training Program in Diabetic PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT03219320
Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathysupportive_care2completed
NCT02056431
Balancing Treatment Outcomes and Medication Burden Among Patients With Symptomatic Diabetic Peripheral NeuropathyNo drug interventionssupportive_careNot Availablecompleted
NCT04457531
LiuWeiLuoBi Granule for the Treatment of Diabetic Peripheral NeuropathyNo drug interventionstreatment0recruiting
NCT04846673
Pregabalin and Alpha-lipoic Acid Combination Versus Each Monotherapy in Patients With Diabetic Peripheral Neuropathytreatment4unknown_status
NCT06544876
Balance Control and Recovery in Diabetes Peripheral NeuropathyNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04555876
Effect of High Tone External Muscle Stimulation on Peripheral Arterial DiseaseNo drug interventionssupportive_careNot Availableunknown_status
NCT04222660
Corneal Nerves Function and StructureNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT02127762
The Effect of Mindfulness Based Stress Reduction in Patients With Painful Diabetic Peripheral NeuropathyNo drug interventionssupportive_careNot Availablecompleted
NCT05848180
Ankle Proprioceptive Training In Patients With Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT01695629
In Vivo Corneal Confocal Microscopy for Non-invasive Assessment of Diabetic Peripheral NeuropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT04006392
An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy PainNo drug interventionstreatmentNot Availableterminated
NCT00553592
Double Blind RCT of Bicifadine SR in Outpatients With Chronic Neuropathic Pain Associated With Diabetestreatment2unknown_status
NCT04984044
Effect of Vitamin D in Patients With Diabetic Peripheral Neuropathy to Alleviate Pain and Improvement of SymptomsNo drug interventionstreatmentNot Availablecompleted
NCT05258240
Effects of Virtual Reality-based Balance Training on Balance of Diabetic Peripheral Neuropathy PatientsNo drug interventionstreatmentNot Availablecompleted
NCT04000867
Treatment for Foot Pain Caused by Diabetic Neuropathy Using Recurrent TransCutaneous Magnetic Stimulation (TCMS)No drug interventionstreatmentNot Availableunknown_status
NCT05414968
A Novel Non-Pharmacological Treatment of Diabetic NeuropathyNo drug interventionsdevice_feasibilityNot Availablerecruiting
NCT01504412
Asian Phase 2 Study for Treatment of Pain Associated With Diabetic Peripheral Neuropathytreatment2completed
NCT03195855
Foot and Ankle Mobilisation in Diabetic Peripheral NeuropathyNo drug interventionstreatmentNot Availablecompleted