Systemic Inflammatory Response Syndrome (SIRS) (DBCOND0053489)

Identifiers

Synonyms
Systemic Inflammatory Response Syndrome / SIRS / Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction / Sepsis syndrome (disorder) / Sepsis syndrome / Systemic inflammatory response syndrome (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03401190
CM4620 Injectable Emulsion Versus Supportive Care in Patients With Acute Pancreatitis and SIRStreatment2completed
NCT03001687
Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic PatientsNo drug interventionspreventionNot Availableunknown_status
NCT02518087
Increased Adsorption Membranes During Cardiopulmonary BypassNo drug interventionstreatmentNot Availablecompleted
NCT02927054
Effect of Education on Resident Physician Knowledge of SepsisNo drug interventionshealth_services_researchNot Availablecompleted
NCT00994877
Thromboelastography in in Patients With SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02279147
Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation.treatment1 / 2unknown_status
NCT03283345
Effect of Menstrual Cycle on Traumatic Systemic ResponseNo drug interventionshealth_services_researchNot Availableunknown_status
NCT05725798
Perioperative Sitagliptin Medication for Reduction of the Inflammatory Response Associated With Cardiopulmonary BypassNot AvailableNot Availablecompleted
NCT00459511
The Importance of Adrenomedullin (AM) on ACTH-Cortisol-Glucose AxisNo drug interventionsNot AvailableNot Availablecompleted
NCT05470907
Registry for Hemoperfusion of Covid-19 ICU PatientsNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00893932
Leptin: a Therapeutic Option for Treating Catabolic States and Malnutrition in Critically Ill PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01708759
IL8 Monitoring and Its Correlation With 251-gene PolymorphismNo drug interventionsNot AvailableNot Availablecompleted
NCT03369275
Cellular Immunotherapy for Septic Shocktreatment2unknown_status
NCT02957175
Immunophenotyping of Patients With Postoperative SIRSNo drug interventionsNot AvailableNot Availableunknown_status
NCT01731106
Cerebral Autoregulation in Non Neurological Critical Patients.No drug interventionsNot AvailableNot Availableterminated
NCT03125941
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomytreatment4completed
NCT04033224
Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan FailureNo drug interventionsNot AvailableNot Availablerecruiting
NCT05663216
Determinants of Vascular Leakage During Systemic Inflammatory Response SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT03617796
Prognostic Value of CD64 Marker for Patients in Intensive Care UnitNo drug interventionsNot AvailableNot Availableunknown_status
NCT01579396
High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac SurgeryNo drug interventionstreatmentNot Availablewithdrawn
NCT00417235
Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU PatientsNo drug interventionsprevention4completed
NCT01998139
Endothelial Microparticles as a Biomarker for Diagnosis and Prognosis in Early SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT05229822
Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel ObstructionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01388725
Comparison the Value of Several Biomarkers of SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT02866825
Studying Complement Inhibition in Complex Cardiac Surgerytreatment2completed
NCT05469048
Near Patient Molecular Testing in SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00739557
A Pilot Study to Evaluate the Systemic Inflammatory Response of Thoracoabdominal Aortic Aneurysm Repair.No drug interventionsNot AvailableNot Availablewithdrawn
NCT00159926
Cleansing of Suction Blood in Cardiac Surgery for Reduced Inflammatory ResponseNo drug interventionstreatment3terminated
NCT01592526
Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy VolunteersNo drug interventionsbasic_science0completed
NCT04681066
A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRStreatment2completed
NCT01322074
Systemic Inflammation Versus Acute Pain in Total Knee Arthroplasty (TKA)No drug interventionsNot AvailableNot Availablecompleted
NCT01296074
Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory ResponsepreventionNot Availablecompleted
NCT03145220
Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)treatment2unknown_status
NCT02903082
Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome?No drug interventionsNot AvailableNot Availableterminated
NCT03939273
The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart SurgerytreatmentNot Availableunknown_status
NCT00254176
Cysteine Supplementation in Critically Ill NeonatesNo drug interventionstreatment2 / 3unknown_status
NCT04624776
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arresttreatment2completed
NCT02077491
The Effect of Protein and Resistance Training on Muscle Mass in Acutely Ill Old Medical PatientsNo drug interventionspreventionNot Availablecompleted
NCT02455180
Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patientstreatment4completed
NCT06028789
AOrtic Surgery: Systemic Inflammatory Response Versus SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT00293592
Dexamethasone for Cardiac Surgery TrialtreatmentNot Availablecompleted
NCT02324140
Inflammatory Response in Aortic Valve ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT02321072
Optimal Oxygenation in the Intensive Care Unitsupportive_care4completed
NCT00448968
The Utility of Ischemia Modified Albumin (IMA) in SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00438269
Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infectiontreatment2completed
NCT05637281
Clinical Efficacy of Indomethacin in Early Treatment of Acute PancreatitistreatmentNot Availablerecruiting
NCT00519350
Towards a High-fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ DamageNo drug interventionsNot AvailableNot Availablecompleted
NCT02820090
The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the MechanismNo drug interventionsNot AvailableNot Availableunknown_status
NCT02728921
The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgerytreatment4completed
NCT02852902
Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study.No drug interventionsNot AvailableNot Availablecompleted
NCT00021502
Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS)treatment3completed
NCT04687384
Systemic and Peritoneal Inflammatory Response In Robotic-assisted And Laparoscopic Surgery for Colon CancerNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06122987
Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shocktreatment4recruiting
NCT03407287
Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid StatusNo drug interventionsNot AvailableNot Availableterminated
NCT02193477
Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal SurgeryNo drug interventionspreventionNot Availablecompleted
NCT00708747
Biseko Versus Albumin in Systemic Inflammatory Response Syndrome (SIRS) Patientstreatment4completed
NCT02055105
Modulation of Molecular Fingerprinting in Pediatric SepsisNo drug interventionsdiagnosticNot Availableunknown_status
NCT02399397
Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokineticstreatment4completed
NCT00490828
Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgeryprevention4completed
NCT00706771
Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Studytreatment2completed
NCT02308371
PPV to Guide Fluid Management in the PICUNo drug interventionsdiagnosticNot Availablecompleted
NCT03066388
Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid ResponsivenessNo drug interventionsdiagnosticNot Availableterminated
NCT01904188
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?No drug interventionsNot AvailableNot Availablerecruiting
NCT00875888
High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic ShockNo drug interventionstreatmentNot Availableterminated
NCT00427388
Steroids In caRdiac Surgery Trial (SIRS Trial)treatment4unknown_status
NCT03427307
Serum Level of Lipopolysaccharide-binding Protein (LBP) and Atherosclerosis in Hemodialysis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06057207
Perioperative Adiponectin and Postoperative Inflammatory Response After Major Abdominal SurgeryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05979207
Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. FalciparumNo drug interventionstreatment1completed
NCT01020409
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT03085615
Feeding the Critically Ill During Phases of Altered Redox StatusNo drug interventionssupportive_careNot Availablecompleted
NCT03863015
IL-6 Inhibition for Modulating Inflammation After Cardiac Arresttreatment2completed
NCT01636232
Vitamin D and Critically Ill PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01042132
Intramedullary Femoral Reaming, Human StudyNo drug interventionstreatmentNot Availablecompleted
NCT02563652
Can Biomarkers Aid in the Prediction of Postoperative Pain and Circulatory Instability After Major Abdominal Surgery?No drug interventionsNot AvailableNot Availablecompleted
NCT00219375
Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in JapanNo drug interventionstreatment4completed
NCT01167075
A Study in Critically Ill Patients Investigating Tolerability and Efficacy of Low-volume Pharmaconutrition (Intestamin)No drug interventionssupportive_careNot Availablecompleted
NCT05969275
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shocktreatment2recruiting
NCT01157299
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCONo drug interventionsNot AvailableNot Availableunknown_status
NCT00708799
Efficacy of Macrolide Immunomodulation in Severe Sepsis.No drug interventionstreatment2terminated
NCT02668406
Study to Obtain Blood and Voided Urine Samples to Improve the Diagnosis of MelioidosisNo drug interventionsNot AvailableNot Availablecompleted
NCT06052436
Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2)No drug interventionstreatment1 / 2recruiting
NCT03876041
Evaluation of Corticosteroid in Systemic Inflammatory Response Syndromeother4completed
NCT05608096
European Registry for Hemadsorption in Sepsis With the Seraph FilterNo drug interventionsNot AvailableNot Availablerecruiting
NCT02902939
Myeloid-Derived Supressor Cells in Cardiac Surgery PatientsNo drug interventionsdiagnosticNot Availablecompleted
NCT05172739
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLCNo drug interventionsbasic_science4recruiting
NCT02320539
MicroRNA Diagnostics in Subarachnoid Hemorrhage 2No drug interventionsNot AvailableNot Availablecompleted
NCT01838525
Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00563030
Bands in Peripheral Blood After Coronary Artery Bypass Grafting With and Without Cardiopulmonary BypassNo drug interventionsNot AvailableNot Availablecompleted
NCT01752348
Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals.No drug interventionsbasic_scienceNot Availablecompleted
NCT02898948
Procalcitonin (PCT) as a Diagnostic Marker of Bacterial Infection in the Patients Admitted for Fever and/or Inflammatory Syndrome to the Internal Medicine DepartmentNot AvailableNot Availablecompleted
NCT06477757
Inflammatory Response and Oxidative Stress in Cardiac Surgery: Min. Invasive vs. Conventional Extracorporeal CirculationNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT03314831
The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT03604731
Persistent Multiorgan Failure in Intensive Care UnitsNo drug interventionsNot AvailableNot Availablecompleted
NCT04580680
Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT)No drug interventionsNot AvailableNot Availablerecruiting
NCT06195267
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Sivelestat) VItreatmentNot Availablenot_yet_recruiting
NCT00356746
Inflammatory Response During Anesthesia and SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00773110
Study of Albumin to Reduce Inflammation Following Surgerytreatment2terminated
NCT02568410
Platelets as Regulators of Inflammation in Cardiac SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT03589495
Safety and Efficacy of Adding Intravenous N-acetyl Cysteine in Colon Surgeriesprevention4completed
NCT03807414
Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05213923
ED Tracking Sheet ImplementationNo drug interventionstreatmentNot Availablecompleted
NCT01236703
Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICUNo drug interventionsNot AvailableNot Availablecompleted
NCT00554021
Infections Related Central Venous CathetersNo drug interventionsNot AvailableNot Availablecompleted
NCT05023954
mSEP: Testing of Physiological and Immune-metabolic Blood Markers for Maternal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02922998
CD64 and Antibiotics in Human SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02083198
Effects of IV Chloride Content on OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT00389337
Sepsis: Prognosis and Evaluation of Early Diagnosis and Intervention (SPEEDI Study)No drug interventionsNot AvailableNot Availableunknown_status
NCT04289506
Validation of Molecular and Protein Biomarkers in SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05142813
A Blood Test to Diagnose Sepsis in Symptomatic Adults and ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT05591924
Early Severe Illness TrAnslational BioLogy InformaticS in HumansNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03876535
Performance Evaluation of the Nanomix eLab® CRP, PCT, and LAC Assays With the Nanomix eLab SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT01493492
Urinary Proteomics Analysis for Sepsis and PrognosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03884595
Early Identification of Sepsis in ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT02052895
Utility of Presepsin in Distinguishing Between Sepsis and SIRSNo drug interventionsNot AvailableNot Availablecompleted
NCT03661450
Evaluation of CDSS in Detection of SIRS and Sepsis in Pediatric PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04901338
Cytokine Hemoadsorption in ECMO PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03784521
Efficacy of Intravenous In-line Filter in Patient Undergoing Cardiac SurgeryNo drug interventionspreventionNot Availablecompleted
NCT05703802
Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.No drug interventionsNot AvailableNot Availablecompleted
NCT02079597
The Role of Ninjurin-1 During Systemic InflammationNo drug interventionsNot AvailableNot Availablecompleted
NCT02704871
The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRSNo drug interventionsNot AvailableNot Availableterminated
NCT01410578
The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUONo drug interventionsNot AvailableNot Availablecompleted
NCT01585909
Evaluation of Intestinal Brush Border Enzyme Function in Critically Ill PatientsNo drug interventionsdiagnosticNot Availablecompleted
NCT03126032
Early Detection of Glycocalyx Damage in Emergency Room PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01333657
The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney InjuriesNo drug interventionsNot AvailableNot Availablecompleted
NCT01493466
Serum Proteomics Analysis for SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01155674
Innate Immune Functions of Immature NeutrophilsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00736827
BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02002676
Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01686776
A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSANo drug interventionsother3completed
NCT04724044
Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumoniatreatment3completed
NCT04254744
SIRS in Cyanotic and Acyanotic Children in Cardiac SurgeryNot AvailableNot Availablecompleted
NCT01649440
Sepsis MetabolomicsNo drug interventionsNot AvailableNot Availablecompleted
NCT04117568
The Role of Emergency Neutrophils and Glycans in Postoperative and Septic PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT01169168
Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU)No drug interventionsNot AvailableNot Availableunknown_status
NCT03082469
Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine RemovalNo drug interventionstreatment4unknown_status
NCT01378169
SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICUNo drug interventionsNot AvailableNot Availablecompleted
NCT00736723
NT-proBNP in ICU Postoperative/Posttraumatic Patients With ShockNo drug interventionsNot AvailableNot Availablecompleted
NCT02127502
VENUS: Septic Gene Expression Using SeptiCyteNo drug interventionsNot AvailableNot Availablecompleted
NCT01921049
Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT01724463
Electronic Application of a Severe Sepsis Screening Tool and Management BundleNo drug interventionsNot AvailableNot Availableunknown_status
NCT03493880
The Analysis of Immuno-Nutrition Index in Advanced Gastric Cancer Receiving Preoperative TreatmentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02728401
Genotypes and Phenotypes in Pediatric SIRS and SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT03288610
Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin LevelNo drug interventionsNot AvailableNot Availablecompleted
NCT02871895
Application of Biomarkers Change to Predict Outcome of Patient With Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02755155
Optimization of Therapeutic Human Serum Albumin Infusion in Selected Critically Ill Patientstreatment4terminated
NCT01293500
Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial)No drug interventionstreatmentNot Availableterminated
NCT01801839
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02887274
Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01469676
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary FunctionNo drug interventionspreventionNot Availablecompleted
NCT01906229
Lung and Systemic Inflammation in the Critically Ill PatientNo drug interventionsNot AvailableNot Availableterminated
NCT01494389
The Changes of CD4+T Lymphocyte Subsets in Septic PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01624246
Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearancetreatment1completed
NCT01392508
IMproved PREdiction of Severe Sepsis in the Emergency DepartmentNo drug interventionsNot AvailableNot Availablecompleted