Progressive Desmoids Tumors (DBCOND0064220)
Identifiers
- Synonyms
- Not Available
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Nirogacestat A gamma-secretase inhibitor used to treat desmoid tumors- Presenilin-1target
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2C19enzyme
- Cytochrome P450 2D6enzyme
- Cytochrome P450 2B6enzyme
- Albumincarrier
- alpha1-acid glycoproteincarrier
- ATP-dependent translocase ABCB1transporter
- Cytochrome P450 2C8enzyme
- Presenilin-2target
- Gamma-secretase subunit APH-1Atarget
- Gamma-secretase subunit PEN-2target
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT01876082 PAZOPANIB Efficacy and Tolerance in Desmoids Tumors No drug interventions treatment 2 completed