NCT03138421
Central Pain Study for ABX-1431 treatment 1 completed NCT05909761
Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy Not Available Not Available recruiting NCT05199688
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) treatment 3 recruiting NCT06561009
Safety and Efficacy of BAFFR CART for Relapsed/ Refractory Neuromyelitis Optica Spectrum Disorder No drug interventions treatment 1 / 2 not_yet_recruiting NCT06502015
Biomarkers in Autoimmune Disease of Nervous System No drug interventions Not Available Not Available not_yet_recruiting NCT05284175
A Study of Orelabrutinib in Patients With AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder treatment Not Available unknown_status NCT05017142
Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD) No drug interventions Not Available Not Available recruiting NCT03819413
Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital No drug interventions Not Available Not Available completed NCT02276963
Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses treatment 1 completed NCT06497374
FcRn Antagonists (Efgartigimod) for Acute NMOSD Attack treatment 2 not_yet_recruiting NCT01623076
The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders No drug interventions Not Available Not Available recruiting NCT05504694
Ofatumumab in AQP4-IgG Seropositive NMOSD treatment 1 / 2 recruiting NCT04201262
An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD treatment 3 active_not_recruiting NCT04886492
CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD) No drug interventions Not Available Not Available enrolling_by_invitation NCT05966467
Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies No drug interventions Not Available Not Available recruiting NCT01777412
Efficacy of Bevacizumab (Avastin) in Treatment of Acute NMO Exacerbations treatment 1 completed NCT01500681
Maintenance Plasma Exchange for Neuromyelitis Optica No drug interventions Not Available Not Available completed NCT03605238
Treatment of Relapsed and/or Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20 No drug interventions treatment 1 withdrawn NCT06374264
Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder No drug interventions treatment Not Available not_yet_recruiting NCT03900221
French Registry for Monitoring Pregnancies for Multiple Sclerosis No drug interventions Not Available Not Available recruiting NCT01845584
Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy. treatment 2 completed NCT05891379
Inebilizumab in Acute Neuromyelitis Optica Spectrum Disorders Not Available Not Available not_yet_recruiting NCT05414487
Effects of Ofatumumab Treatment on Immune Cells and Meningeal Lymphatic Drainage in Patients With Demyelinating Diseases Not Available Not Available recruiting NCT05346354
Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD treatment 2 / 3 recruiting NCT01892345
A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study) treatment 3 terminated NCT05551598
Efficacy and Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Neuromyelitis Optica Spectrum Disorder (NMOSD) treatment 2 completed NCT02893111
Efficacy and Safety of Bortezomib as add-on Treatment in Relapsing Neuromyelitis Optica Spectrum Disorder treatment 2 completed NCT06180278
Long-term, Open-label, Safety Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorder (NMOSD) treatment 4 recruiting NCT04256252
Rituximab at Low dosE for neuromyelitiS optiCa spectrUm disordEr (RESCUE) treatment 4 completed NCT04155424
A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder treatment 2 / 3 terminated NCT05549258
Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder treatment 2 recruiting NCT04660539
A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD) treatment 3 completed NCT04561557
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System treatment 0 recruiting NCT06474520
Efficacy and Safety of Calculus Bovis Sativus (CBS) for Idiopathic Inflammatory Demyelinating Disease (CBSinIIDD) treatment Not Available not_yet_recruiting NCT04064944
Comparison of the Efficacy and Safety of Immunoadsorption and Plasma Exchange for Acute Attack of Refractory Neuromyelitis Optica Spectrum Disorders No drug interventions treatment 2 not_yet_recruiting NCT02003144
An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients treatment 3 completed NCT05269667
A Study In Neuromyelitis Optica Spectrum Disorder (NMOSD) With Satralizumab As An Intervention treatment 4 terminated NCT05314010
A Study of MIL62 in Patients With Neuromyelitis Optica Spectrum Disorder (NMOSD) No drug interventions treatment 3 recruiting NCT03002038
Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients treatment 2 / 3 completed NCT05403138
Safety and Efficacy of Daratumumab in Patients With Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorders treatment 2 / 3 recruiting NCT02028884
Efficacy and Safety Study of Satralizumab (SA237) as Add-on Therapy to Treat Participants With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD) treatment 3 completed NCT02073279
Efficacy and Safety Study of Satralizumab (SA237) as Monotherapy to Treat Participants With Neuromyelitis Optica (NMO) and Neuromyelitis Optica Spectrum Disorder (NMOSD) treatment 3 completed NCT03062579
A Longitudinal Study of ACTEMRA® (Tocilizumab) as Monotherapy in Highly Active NMOSD treatment 1 / 2 completed NCT02809079
Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients treatment 4 unknown_status NCT03350633
Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders treatment 2 / 3 completed NCT06413654
A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD) No drug interventions treatment 2 / 3 recruiting NCT06212245
A Clinical Research Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorders treatment 4 not_yet_recruiting NCT06485232
Universal CAR-T Cells in Patients With Refractory Autoimmune Diseases of the Nervous System. No drug interventions treatment 0 not_yet_recruiting NCT04670770
An Open Label Study of the Effects of SHR1459 in NMOSDs Patients treatment 2 completed NCT03330418
A Phase III Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Neuromyelitis Optica Spectrum Disorders No drug interventions treatment 3 recruiting NCT05871658
Efficacy of Electroacupuncture in NMOSD Patients With Pain: Study Protocol No drug interventions treatment Not Available completed NCT02836327
Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders No drug interventions Not Available Not Available unknown_status NCT06249438
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy No drug interventions treatment 1 recruiting NCT02850705
The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS) No drug interventions Not Available Not Available completed NCT04146285
A Phase I Clinical Trial of BAT4406F Injection in Patients With Neuromyelitis Optica Spectrum Disorders No drug interventions treatment 1 recruiting NCT05204459
MS-ResearchBiomarkerS No drug interventions Not Available Not Available recruiting NCT05730699
Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE) treatment 3 recruiting NCT04101058
Treatment Response Among Chinese Neuromyelitis Optica Spectrum Disorders No drug interventions Not Available Not Available unknown_status NCT02021825
Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders treatment 4 unknown_status NCT06541626
Sun Yat-Sen Cohort of CNS Idiopathic Inflammatory Demyelinating Diseases No drug interventions Not Available Not Available recruiting NCT02889965
The French Multiple Sclerosis Registry No drug interventions Not Available Not Available unknown_status NCT06068829
Inebilizumab and Rituximab in Neuromyelitis Optica Spectrum Disorders Not Available Not Available not_yet_recruiting NCT04388072
An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit No drug interventions Not Available Not Available completed NCT05414890
Sensitivity and Specificity of TSA-CBA for Autoantibodies Against Neural Antigen Determination No drug interventions Not Available Not Available unknown_status NCT06443333
National, Multicentric Registry Study on Neuroimmunological Diseases in China No drug interventions Not Available Not Available recruiting NCT05896605
Monitoring of Azathioprine Metabolite Concentrations and Cytokine Levels in Neuromyelitis Optica Spectrum Disorder treatment 4 completed NCT05154370
China National Registry of Neuro-Inflammatory Diseases No drug interventions Not Available Not Available recruiting NCT05432713
A Study of LP-168 in Healthy Volunteers No drug interventions treatment 1 completed NCT04106830
Clinical and Imaging Patterns of Neuroinflammation Diseases in China (CLUE) Not Available Not Available recruiting NCT03829566
Autologous Transplant To End NMO Spectrum Disorder treatment 2 / 3 withdrawn NCT06548620
A Study of RD06-04 in Patients With Active Autoimmune Diseases No drug interventions treatment 0 not_yet_recruiting NCT06280755
Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. No drug interventions Not Available Not Available not_yet_recruiting NCT03766347
Pediatric NMOSD Observational Study No drug interventions Not Available Not Available completed NCT05145361
Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder (NMOSD) No drug interventions treatment 0 recruiting NCT04355611
Epidemiological Characteristics of COVID-19 in Patients With MS or NMO No drug interventions Not Available Not Available completed NCT05974293
A Phase IIb Study of Nabiximols for Spasticity Due to Neuromyelitis Optica Spectrum Disorders treatment 2 not_yet_recruiting NCT05004493
Biorepository and Registry for Plasma Exchange Patients No drug interventions Not Available Not Available recruiting NCT04227470
A Study of HBM9161 in NMOSD Patients treatment 1 completed NCT05154734
Efficacy and Safety of Belimumab in Neuromyelitis Optica Spectrum Disorders basic_science 1 / 2 completed NCT05792462
Efficacy and Safety of Baricitinib in Neuromyelitis Optica Spectrum Disorders basic_science 1 / 2 recruiting NCT05840055
ACT With NMOSD Patients and Caregivers Pilot Study No drug interventions supportive_care Not Available recruiting NCT04822623
Imaging Evaluation of Central Nervous Autoimmune Diseases No drug interventions Not Available Not Available unknown_status