NCT03314324
A Study of Patient Preference Between ODM-201 and Enzalutamide in Men With Metastatic Castrate-resistant Prostate Cancer other 2 active_not_recruiting NCT04188587
177Lu-PSMA-I＆T PSMA Radioligand Therapy in Metastatic Castration-Resistant Prostate Cancer No drug interventions treatment 2 unknown_status NCT03177187
Combination Study of AZD5069 and Enzalutamide. health_services_research 1 / 2 terminated NCT01681433
OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone treatment 2 terminated NCT02426333
Optimizing Abiraterone Therapy No drug interventions Not Available Not Available completed NCT04056754
Study of Abiraterone Acetate in Subjects With Metastatic Castration Resistant Prostate Cancer treatment 3 completed NCT02044354
Patient Preference Between Cabazitaxel and Docetaxel in Metastatic Castrate-resistant Prostate Cancer other 3 unknown_status NCT02047253
Phase 2 Trial of Carfilzomib for Metastatic Castration-resistant Prostate Cancer Following Treatment treatment 2 completed NCT06228053
Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer treatment 2 recruiting NCT02111577
Phase III Study of DCVAC/PCa Added to Standard Chemotherapy for Men With Metastatic Castration Resistant Prostate Cancer treatment 3 completed NCT03778047
A Study Evaluating Enzalutamide Pharmacokinetics and Pharmacodynamics, and Related Changes After Drug Switch treatment 1 completed NCT02288247
A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone treatment 3 completed NCT06520345
The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT-GLOBAL) treatment 3 not_yet_recruiting NCT02266745
A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts treatment 2 active_not_recruiting NCT06136598
A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001) treatment 1 active_not_recruiting NCT04853498
A Study to Evaluate the Tolerance and Pharmacokinetics of TQB3720 Tablets No drug interventions treatment 1 unknown_status NCT02787005
Study of Pembrolizumab (MK-3475) in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)(MK-3475-199/KEYNOTE-199) treatment 2 completed NCT05005728
XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 2 recruiting NCT04268628
A Study of Pharmacodynamic and Genetic Parameters of Abira-DES Study Participants (NCT02217566) - Participants With Metastatic Castration-Resistant Prostate Cancer Treated With Abiraterone Acetate Following Unresponsive Treatment With Diethylstilbestrol No drug interventions Not Available Not Available completed NCT02991911
A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer treatment 1 completed NCT04458311
Abiraterone Acetate in Combination With Tildrakizumab health_services_research 1 / 2 terminated NCT04256993
PRECISE, a Study to Gather More Information About Bone Fractures and Survival in Castration-resistant PRostate Cancer (CRPC) patiEnts Treated With Radium-223 in Routine Clinical practIce in SwedEn Not Available Not Available completed NCT05081193
Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer treatment 2 recruiting NCT05766371
Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer treatment 2 recruiting NCT04846478
Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC treatment 1 active_not_recruiting NCT04869488
A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer treatment 2 unknown_status NCT01541007
A Study Looking at Novel Scheduling of Cabazitaxel for Patients With Metastatic Prostate Cancer treatment 2 completed NCT05588609
Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers treatment 2 recruiting NCT05558956
Total Body PET-CT Imaging of Prostate Cancer Using Illuccix diagnostic 0 recruiting NCT03568656
Study to Evaluate CCS1477 in Advanced Tumours treatment 1 / 2 recruiting NCT01663415
A Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Naïve, Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer treatment 2 withdrawn NCT05113537
Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer treatment 1 / 2 recruiting NCT04486937
SC10914 Monotherapy for the mCRPC With g/s BRCA Mutation No drug interventions treatment 1 / 2 unknown_status NCT05888532
64Cu-GRIP B in Patients With Advanced Malignancies diagnostic 1 / 2 recruiting NCT06383052
A Phase 1/2 Study of 177Lu-NYM032 Injection in mCRPC treatment 1 / 2 recruiting NCT05369000
Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer (mCRPC) Resistant Prostate Cancer treatment 1 / 2 recruiting NCT05219500
Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST). No drug interventions treatment 2 recruiting NCT05603559
177Lu-P17-087/177Lu-P17-088 in Patients With Metastatic Castration-resistant Prostate Cancer treatment 0 completed NCT04227275
A Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 terminated NCT03780075
Lu177-EB-PSMA617 Radionuclide Treatment in Patients With Metastatic Castration-resistant Prostate Cancer treatment 1 unknown_status NCT05725070
Phase 0/1 Study of 212Pb-NG001 in mCRPC No drug interventions treatment 0 completed NCT05917470
A Clinical Study of ONCT-534 in Subjects With Metastatic Castration-resistant Prostate Cancer. No drug interventions treatment 1 / 2 recruiting NCT06531499
A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study treatment 1 not_yet_recruiting NCT05245006
PET Imaging Study of 89Zr-DFO-YS5 in Men With Prostate Cancer No drug interventions diagnostic 1 recruiting NCT06052306
A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Men With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC) No drug interventions treatment 1 recruiting NCT05519449
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01) No drug interventions treatment 1 recruiting NCT06303713
LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer treatment 1 recruiting NCT05241613
A Study of AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer No drug interventions treatment 1 terminated NCT03570619
Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations treatment 2 completed NCT06067841
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer No drug interventions treatment 1 recruiting NCT02441517
A Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer After Docetaxel and/or Cabazitaxel Treatment treatment 4 terminated NCT04556617
PLX2853 in Combination With Abiraterone Acetate and Prednisone and in Combination With Olaparib in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) treatment 1 / 2 terminated NCT01972217
Ph II Study to Evaluate Olaparib With Abiraterone in Treating Metastatic Castration Resistant Prostate Cancer. treatment 2 completed NCT04769817
ProsTIC Registry of Men Treated With PSMA Theranostics No drug interventions Not Available Not Available recruiting NCT02095717
Multicenter Study Comparing Taxotere Plus Curcumin Versus Taxotere Plus Placebo Combination in First-line Treatment of Prostate Cancer Metastatic Castration Resistant (CURTAXEL) treatment 2 terminated NCT03414034
Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer treatment 2 completed NCT02952534
A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency treatment 2 completed NCT04408924
Abemaciclib (LY2835219) in Men With Heavily Treated Metastatic Castration-Resistant Prostate Cancer treatment 2 completed NCT04068896
Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy No drug interventions treatment 1 / 2 completed NCT02123758
A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer treatment 1 active_not_recruiting NCT03137758
A Phase I Study of PCUR-101 in Combination With Androgen Suppression Therapy in the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer treatment 1 terminated NCT03692663
Study of Anti-PSMA CAR NK Cell (TABP EIC) in Metastatic Castration-Resistant Prostate Cancer treatment 0 unknown_status NCT06193486
Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC treatment 1 recruiting NCT01818986
Sipuleucel-T and Stereotactic Ablative Body Radiation (SABR) for Metastatic Castrate-resistant Prostate Cancer (mCRPC) treatment 2 completed NCT04801186
Retrospective Study to Describe the Real-world Treatment Patterns and Associated Clinical Outcomes in Patients With Metastatic Castration-resistant Prostates Cancer No drug interventions Not Available Not Available completed NCT05405439
To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer treatment 1 / 2 terminated NCT02655822
Phase 1/1b Study to Evaluate the Safety and Tolerability of Ciforadenant Alone and in Combination With Atezolizumab in Advanced Cancers treatment 1 completed NCT06492122
Study With [225Ac]Ac-FL-020 in mCRPC Participants No drug interventions treatment 1 not_yet_recruiting NCT05720130
Phase Ib/IIa Dose Escalation and Expansion Study of [²¹²Pb]Pb-ADVC001 in Metastatic Castration Resistant Prostate Cancer (TheraPb - Phase I/II Study). No drug interventions treatment 1 / 2 recruiting NCT02424448
Study to Determine the Feasibility, Evaluability and Variability in Markers of Drug Action in Castration Resistant Prostate Cancer No drug interventions Not Available Not Available completed NCT02125357
Sequencing Abiraterone and Enzalutamide in mCRPC other 2 completed NCT01540526
Pharmacodynamic Study With FLT-PET/CT in Patients With Prostate/Other Solid Malignancies Treated With High Dose Axitinib treatment 1 completed NCT04647526
Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment treatment 3 active_not_recruiting NCT06229366
[Ac-225]-PSMA-62 Trial in Biochemically Recurrent and Metastatic Castration Resistant Prostate Cancer No drug interventions treatment 1 recruiting NCT04575766
A Study of FT-7051 in Men With MCRPC No drug interventions treatment 1 terminated NCT01750866
Cabazitaxel in Men 75 Years of Age or Older With Castration-Resistant Prostate Cancer treatment 2 withdrawn NCT01090765
A Phase I/II Study of TRC105 in Metastatic Castrate Resistant Prostate Cancer (CRPC) treatment 1 / 2 completed NCT06221774
Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological Tumors treatment 1 / 2 not_yet_recruiting NCT04703920
Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer treatment 1 recruiting NCT06402331
FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) No drug interventions treatment 2 / 3 recruiting NCT06318273
A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer No drug interventions treatment 1 recruiting NCT03531827
Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment treatment 2 terminated NCT05544227
Phase 1 Trial of SYNC-T - Immunotherapy for Advanced/Metastatic Castration-Resistant Prostate Cancer No drug interventions treatment 1 active_not_recruiting NCT05650476
Pre-approval Single-patient Expanded Access for Talazoparib (PF-06944076) Not Available Not Available available NCT04000776
3TMPO (Triple-Tracer Strategy Against Metastatic Prostate Cancer No drug interventions Not Available Not Available completed NCT05570994
177Lu-HTK03170 in mCRPC With PSMA Positive Disease treatment 1 / 2 recruiting NCT04754191
Enfortumab Vedotin as Monotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 2 recruiting NCT06056791
Study of INKmune in Patients With mCRPC (CaRe Prostate) No drug interventions treatment 1 / 2 recruiting NCT05489991
A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) No drug interventions treatment 1 / 2 terminated NCT06401980
Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC) treatment 2 not_yet_recruiting NCT04109729
Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer treatment 1 / 2 recruiting NCT04751929
Abemaciclib With or Without Atezolizumab for mCRPC treatment 2 active_not_recruiting NCT02987829
Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients No drug interventions treatment 1 / 2 completed NCT04879589
Phase 1 Study of ATRS-2002 in Healthy Male Adults treatment 1 withdrawn NCT06250244
177Lu-LNC1011 in Patients With Metastatic Castration-resistant Prostate Cancer treatment Not Available recruiting NCT02566772
Study of TAS3681 in Metastatic Castration Resistant Prostate Cancer No drug interventions treatment 1 completed NCT02471469
Personalizing Enzalutamide Therapy by Understanding the Relation Between Tumor mRNAs, miRNAs and Treatment Response Not Available Not Available completed NCT02705469
A Study of ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer No drug interventions treatment 1 completed NCT03042312
Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy treatment 2 terminated NCT06480110
Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate Cancer treatment 1 / 2 recruiting NCT04629781
Open-label Dose Escalation Phase 1b Trial of a New Micellar Docetaxel Compound in Patients With mCRPC treatment 1 terminated NCT03176381
Tissue Predictors of Abiraterone Benefit No drug interventions Not Available Not Available completed NCT05413850
Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection treatment 1 / 2 recruiting NCT04986423
ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer treatment 2 recruiting NCT05613738
177Lu-PSMA-EB-01 in Patients With Metastatic Castration-resistant Prostate Cancer treatment Not Available recruiting NCT02141438
Observational Study for the Evaluation of Long-term Safety of Radium-223 Used for the Treatment of Metastatic Castration Resistant Prostate Cancer Not Available Not Available active_not_recruiting NCT06380738
Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed) No drug interventions Not Available Not Available recruiting NCT02987543
Study of Olaparib (Lynparza™) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study) treatment 3 completed NCT05533203
Safety of Prodencel in the Treatment of Metastatic Castration-resistant Prostate Cancer (mCRPC) No drug interventions treatment 1 unknown_status NCT03328364
A Registry Based Study Evaluating Overall Survival and Treatment Length in mCRPC Patients Treated With Enzalutamide in Sweden Not Available Not Available completed NCT04179864
A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate Cancer treatment 1 / 2 active_not_recruiting NCT05252364
A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in Patients With Metastatic Castration-Resistant Prostate Cancer No drug interventions treatment 1 completed NCT05327621
Pamiparib in mCRPC With HRD or BRCA1/2 Mutation treatment 2 recruiting NCT06514521
Post Marketing Study on Pluvicto in Korea No drug interventions Not Available Not Available not_yet_recruiting NCT02286921
Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance treatment 2 completed NCT01517802
A Study That Provides Long-term Safety Follow-up and Examines Long-term Exposure to Abiraterone Acetate treatment 3 completed NCT04038502
Carboplatin or Olaparib for BRcA Deficient Prostate Cancer health_services_research 2 recruiting NCT05823402
Use of SPECT-CT for Comparison of Dosimetry Methods in PSMA-targeted Radioligand Therapy (SPECTacular Study) No drug interventions diagnostic Not Available recruiting NCT02744287
Safety and Activity Study of PSCA-Targeted CAR-T Cells (BPX-601) in Subjects With Selected Advanced Solid Tumors treatment 1 / 2 suspended NCT03835533
Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations treatment 1 completed NCT03454451
CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers treatment 1 completed NCT03658447
PRINCE (PSMA-lutetium Radionuclide Therapy and ImmuNotherapy in Prostate CancEr) treatment 1 / 2 completed NCT04249947
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC) treatment 1 active_not_recruiting NCT04158245
18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies other 2 completed NCT06029998
Bortezomib in Patients With Metastatic Castration-Resistant Prostate Cancer With PTEN Deletion treatment 2 recruiting NCT06100705
Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC treatment 2 recruiting NCT06031805
PRostate Olaparib Real World Evidence Study No drug interventions Not Available Not Available recruiting NCT05156905
Study of Docetaxel Combined With Cirmtuzumab in Metastatic Castration Resistant Prostate Cancer treatment 1 recruiting NCT05176483
Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors treatment 1 recruiting NCT02607228
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 (Alobresib) as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer treatment 1 / 2 terminated NCT05489211
Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03) treatment 2 recruiting NCT04104893
A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation treatment 2 recruiting NCT06099093
Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan diagnostic 4 recruiting NCT03236688
Detection of ARv7 in the Plasma of Men With Advanced Metastatic Castrate Resistant Prostate Cancer (MCRP) No drug interventions Not Available Not Available suspended NCT05011188
FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 / 2 recruiting NCT04676607
SHR7390 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer No drug interventions treatment 2 completed NCT05673109
A Study of AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer No drug interventions treatment 1 terminated NCT05955209
Clinical Study on the Efficacy and Safety of RC48-ADC in the Treatment of Metastatic Castration Resistant Prostate Cancer (mCRPC) treatment 2 not_yet_recruiting NCT06242509
Intestinal Akkermansia Muciniphila in Prostate Cancer No drug interventions Not Available Not Available not_yet_recruiting NCT02711956
A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 1 / 2 completed NCT03774056
A Study Evaluating Tolerability, Pharmacokinetics, and Preliminary Efficacy of HC-1119 in Patients. treatment 1 completed NCT03041285
Idronoxil Suppository Combine With Radiotherapy for Metastatic Prostate Cancer treatment 1 terminated NCT05655715
Checkpoint Inhibitors and SBRT for mCRPC treatment 2 recruiting NCT01942837
Study of Enzalutamide in Patients With Castration-resistant Prostate Cancer treatment 2 completed NCT04726332
Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101) treatment 1 terminated NCT03737370
Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer treatment 1 active_not_recruiting NCT05177770
Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer treatment 2 terminated NCT03752099
To Evaluate Safety and Tolerability of VERU-111 in Men With Advanced Metastatic Castration Resistant Prostate Cancer treatment 1 / 2 terminated NCT04887506
TAVT-45 (Abiraterone Acetate) Granules in Patients With Prostate Cancer treatment 3 completed NCT04844749
Efficacy Evaluation of VERU-111 for mCRPC in Patients Who Have Failed at Least One Androgen Receptor Targeting Agent treatment 3 terminated NCT06104449
A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-005) treatment 1 active_not_recruiting NCT06529549
Efficacy and Safety of Organoid-Based Drug Sensitivity Screening to Guide the Treatment of mCRPC Patients Progressed After First-line Treatment No drug interventions Not Available Not Available recruiting NCT01732549
A Proof of Concept Study of Maintenance Therapy With Tasquinimod in Patients With Metastatic Castrate-resistant Prostate Cancer Who Are Not Progressing After a First Line Docetaxel Based Chemotherapy treatment 2 terminated NCT05762536
Docetaxel or Cabazitaxel With or Without Darolutamide in mCRPC treatment 2 recruiting NCT03829436
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers treatment 1 completed NCT01594918
Phase I Cabazitaxel, Mitoxantrone, and Prednisone Metastatic Castration-Resistant Prostate Cancer treatment 1 completed NCT06517719
Real-world Experience With Lutetium Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer No drug interventions Not Available Not Available not_yet_recruiting NCT03437941
Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With mCRPC treatment 1 / 2 completed NCT03792841
Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC treatment 1 completed NCT02975934
A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency treatment 3 active_not_recruiting NCT04676334
CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib treatment 3 completed NCT03230734
Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer treatment 2 recruiting NCT04740034
A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma No drug interventions treatment 1 completed NCT05171816
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort) treatment 3 active_not_recruiting NCT05125016
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer treatment 1 / 2 recruiting NCT03729596
MGC018 With or Without MGA012 in Advanced Solid Tumors treatment 1 / 2 terminated NCT04179396
Study of Oral Rucaparib With Other Anticancer Agents in Metastatic Castration Resistant Prostate Cancer Patients (RAMP) treatment 1 completed NCT02405858
A Study of Abiraterone Acetate in Metastatic Castration-Resistant Prostate Cancer Participants Who Responded Poorly to the First-line Combined Androgen Blockade Therapy treatment 4 completed NCT02008058
Observational Longitudinal Study of Pain in Men With Metastatic Castrate-Resistant Prostate Cancer No drug interventions Not Available Not Available completed NCT04927663
11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression No drug interventions diagnostic 1 recruiting NCT00730639
A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies treatment 1 completed NCT06439225
Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes treatment 3 not_yet_recruiting NCT03761225
Masitinib Plus Docetaxel in Metastatic Castration-resistant Prostate Cancer treatment 3 completed NCT06329830
177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancer treatment 1 / 2 not_yet_recruiting NCT04509557
[177Lu]Ludotadipep Treatment in Patients With Metastatic Castration-resistant Prostate Cancer. treatment 1 completed NCT05457257
Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations treatment 4 active_not_recruiting NCT03845166
A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors treatment 1 active_not_recruiting NCT03085966
Autologous Immune Cell Therapy in Combination With LHRH-a in Patients With mCRPC No drug interventions treatment 1 / 2 unknown_status NCT02495974
European Observational Study of Enzalutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC) Not Available Not Available completed NCT05340374
Cabazitaxel in Combination With 177Lu-PSMA-617 in Metastatic Castration-resistant Prostate Cancer treatment 1 / 2 recruiting NCT00428220
A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study. treatment Not Available completed NCT03732820
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer treatment 3 active_not_recruiting NCT01606982
Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy Not Available Not Available approved_for_marketing NCT02116582
A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer treatment 4 completed NCT02091531
Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients treatment 2 completed NCT02861573
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365) treatment 1 / 2 recruiting NCT03641560
A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based Chemotherapy treatment 4 completed NCT04060394
Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC treatment 1 / 2 completed NCT01650194
A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients treatment 2 completed NCT05613894
Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 1 recruiting NCT06568562
XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 2 not_yet_recruiting NCT04253262
A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer treatment 1 / 2 active_not_recruiting NCT05301062
A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels Not Available Not Available terminated NCT04666129
Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer treatment 1 active_not_recruiting NCT03682289
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors treatment 2 recruiting NCT05458544
[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application treatment 1 / 2 recruiting NCT06533644
A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castrate-Resistant Prostate Cancer No drug interventions treatment 1 not_yet_recruiting NCT04634344
Assess the Safety, Tolerability, PK and Anti-tumor Efficacy of DZD2269 in Patients With MCRPC No drug interventions treatment 1 terminated NCT04631601
Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC) treatment 1 / 2 terminated NCT06228404
Clinical Study of Safety and Efficacy of Enhanced PSMA CAR- T in Refractory CRPC No drug interventions treatment 0 recruiting NCT03776968
A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics treatment 1 completed NCT05700669
Study To Assess Safety And Efficacy Of AsiDNA In Combination With Olaparib In Participants With Recurrent Solid Tumors treatment 1 / 2 recruiting NCT05521412
EValuation of radIOLigand Treatment in mEn With Metastatic Castration-resistant Prostate Cancer With [161Tb]Tb-PSMA-I&T No drug interventions treatment 1 / 2 active_not_recruiting NCT04225910
Clinical Trial of Ac225-PSMA Radioligand Therapy of Metastatic Castration-resistant Prostate Cancer No drug interventions treatment 0 unknown_status NCT05124795
IMU-935 in Patients With Progressive, Metastatic Castration Resistant Prostate Cancer No drug interventions treatment 1 terminated NCT03403595
177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer treatment 1 unknown_status NCT05401214
Pre-approval Access Single Patient Request for Niraparib / Abiraterone Acetate Combination (Nira/AA Combination) Not Available Not Available approved_for_marketing NCT03770455
Avelumab Plus 2nd-generation ADT in African American Subjects With mCRPC treatment 2 terminated NCT05127850
MENCORE-2: Audio Recordings to Improve Decision-making in Advanced Prostate Cancer No drug interventions health_services_research Not Available completed NCT03454750
Radiometabolic Therapy (RMT) With 177Lu PSMA 617 in Advanced Castration Resistant Prostate Cancer (CRPC) treatment 2 active_not_recruiting NCT05262608
The Study of Olaparib in Newly Diagnosed mCRPC Patients With HRR Gene Mutation treatment 2 unknown_status NCT05682443
ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC treatment 1 / 2 recruiting NCT04586543
Clinical Trial of Selegiline Plus Docetaxel for the Treatment of Metastatic, Castrate-resistant Prostate Adenocarcinoma treatment 2 recruiting NCT04363164
Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression treatment 2 recruiting NCT03012321
Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects treatment 2 active_not_recruiting NCT04419402
Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer treatment 2 active_not_recruiting NCT06155084
A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients No drug interventions treatment 1 recruiting NCT04925284
Study of XB002 in Subjects With Solid Tumors (JEWEL-101) treatment 1 active_not_recruiting NCT04237584
A Study Comparing ARB With Radium-223 vs ARB Therapy With Placebo and the Effect Upon Survival for mCRPC Patients treatment 3 terminated NCT05383079
Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men With Metastatic Castration-Resistant Prostate Cancer treatment 1 / 2 recruiting NCT05116579
Circulating Tumor DNA (ctDNA) Monitoring in the Assessment and Prediction of the Efficacy of PARP Inhibitors (PARPi) No drug interventions Not Available Not Available recruiting NCT06190899
Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer treatment 1 / 2 recruiting NCT02232230
A Multicenter Trial Enrolling Men With Advanced Prostate Cancer Who Are to Receive Combination Radiation and Sipuleucel-T Not Available Not Available completed NCT01977651
A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide treatment 4 completed NCT04089553
An Open-label, Phase II Study of AZD4635 in Patients With Prostate Cancer treatment 2 completed NCT02130947
Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer Receiving Abiraterone or Enzalutamide No drug interventions supportive_care Not Available withdrawn NCT05983198
A Phase I/II, Open-label, Multi-center Study of [225Ac]Ac-PSMA-R2 in Men With PSMA-positive Prostate Cancer With or Without Prior 177Lu-PSMA Radioligand Therapy. No drug interventions treatment 1 / 2 recruiting NCT06377683
Clinical Evaluation of 177Lu-DansyI-PSMA (LNC1011) in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 1 recruiting NCT04516161
EPIX, a Study to Gather More Information About Characteristics of Patients and Other Factors Which May Contribute to Survival Over a Long Period of Time in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Treated With Radium-223 (Xofigo) Not Available Not Available completed NCT03071328
INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers other 0 completed NCT05701007
Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in Finland Not Available Not Available completed NCT02740985
A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies treatment 1 completed NCT06344715
Phase 1 Study Evaluating Safety and Tolerability of SL-T10, GX-I7, and Pembrolizumab Triple Combination in mCRPC. treatment 1 recruiting NCT06134232
Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T treatment 3 not_yet_recruiting NCT03549000
A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies. No drug interventions treatment 1 terminated NCT06551324
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1). treatment 3 not_yet_recruiting NCT03903835
ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer treatment 3 recruiting NCT03972657
A Trial to Find Out if REGN5678 is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors treatment 1 / 2 recruiting NCT05107674
A Study of NX-1607 in Adults With Advanced Malignancies treatment 1 recruiting NCT06237491
The Safety and Dosimetry Study of 177Lu-LNC1003 Injection treatment 1 not_yet_recruiting NCT05208229
The Role of WB-MRI in the Evaluation of Prostate Cancer Patients Treated With Lutetium - Prostate Specific Membrane Antigen (Lu-PSMA) No drug interventions Not Available Not Available terminated NCT05032040
A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies treatment 2 recruiting NCT06046040
TmPSMA-02 in mCRPC No drug interventions treatment 1 recruiting NCT03899467
The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC treatment 2 completed NCT02907372
Impact of New Generation Hormono-therapy on Cognitive Functions in Elderly Patients Treated for a Metastatic Prostate Cancer No drug interventions diagnostic Not Available completed NCT06241846
A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC No drug interventions treatment 2 recruiting NCT05658003
A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer treatment 2 active_not_recruiting NCT03896984
Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second Line Treatment With Novel Anti-Hormone Therapy or RadIum-223 (Xofigo). Not Available Not Available completed NCT05579184
[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application_2 treatment 2 active_not_recruiting NCT03460977
Mevrometostat Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma treatment 1 recruiting NCT03724747
Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Antitumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate Alone and in Combination With Darolutamide, in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 active_not_recruiting NCT06004661
Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function treatment 2 recruiting NCT03030885
Use of an Experimental Radiopharmaceutical (131I-MIP-1095) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC) treatment 1 completed NCT03074032
Safety, Tolerability and Pharmacokinetics of ONC1-0013B in Patients With Progressive Metastatic Castration-resistant Prostate Cancer No drug interventions treatment 1 completed NCT06334432
Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT04825652
177Lu-PSMA-617 Managed Access Program for mCRPC Patients Not Available Not Available no_longer_available NCT03811652
A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors No drug interventions treatment 1 completed NCT00684970
Phase IIB Clinical Trial of Hamsa-1™ in Metastatic Castration Resistant Prostate Cancer (CRPC) No drug interventions treatment 2 unknown_status NCT05670106
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC treatment 2 active_not_recruiting NCT04015622
PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA treatment 2 recruiting NCT04597125
Investigation of Radium-223 Dichloride (Xofigo), a Treatment That Gives Off Radiation That Helps Kill Cancer Cells, Compared to a Treatment That Inactivates Hormones (New Antihormonal Therapy, NAH) in Patients With Prostate Cancer That Has Spread to the Bone Getting Worse on or After Earlier NAH treatment 4 active_not_recruiting NCT03712930
Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency treatment 2 terminated NCT06126731
Combination Study of Antibiotics With Enzalutamide (PROMIZE) treatment 1 / 2 recruiting NCT04862091
Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA® in Patients With Metastatic Castration-resistant Prostate Cancer treatment 2 completed NCT05425862
Pidnarulex and Talazoparib in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 suspended NCT01692262
Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer. screening 1 completed NCT03207867
A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma treatment 2 terminated NCT04052204
Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors treatment 1 / 2 terminated NCT04691804
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer treatment 3 recruiting NCT02826772
Safety, Tolerability, and PK of GT0918 (Proxalutamide) in Subjects With Metastatic Castrate Prostate Cancer treatment 1 completed NCT03480646
ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 / 2 unknown_status NCT05806814
Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer treatment 1 recruiting NCT06136650
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) treatment 3 recruiting NCT02649790
Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications treatment 1 / 2 active_not_recruiting NCT03874884
177Lu-PSMA-617 Therapy and Olaparib in Patients With Metastatic Castration Resistant Prostate Cancer treatment 1 recruiting NCT06249750
Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer treatment 2 recruiting