Ataxia-Telangiectasia (A-T) (DBCOND0074226)

Identifiers

Synonyms

Ataxia-Telangiectasia / Ataxia Telangiectasia (AT) / Ataxia Telangiectasia / Ataxia-telangiectasia syndrome (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02246491	Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia	No drug interventions	basic_science	Not Available	terminated
NCT00187057	Study for Treatment of Cancer in Children With Ataxia-telangiectasia	Asparaginase Escherichia coli Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Doxorubicin Etoposide Mercaptopurine Methotrexate Prednisone Procarbazine Vinblastine Vincristine	treatment	Not Available	completed
NCT02733679	Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone	Metformin Pioglitazone	treatment	4	completed
NCT01793168	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	No drug interventions	Not Available	Not Available	recruiting
NCT00656409	Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)	No drug interventions	basic_science	3	completed
NCT03563053	Extension Treatment Using EryDex System in Patients With AT Who Participated in the ATTeST-IEDAT-02-2015 Study	No drug interventions	treatment	3	terminated
NCT06193200	Evaluate the Neurological Effects of EryDex on Subjects With A-T	Dexamethasone	treatment	3	recruiting
NCT06324877	Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	Nicotinamide riboside	health_services_research	Not Available	not_yet_recruiting
NCT03357978	Susceptibility to Infections, Tumor Risk and Liver Disease in Patients With Ataxia Telangiectasia	No drug interventions	diagnostic	Not Available	unknown_status
NCT02309632	Pancreatic Cancer Screening of High-Risk Individuals in Arkansas	No drug interventions	screening	Not Available	withdrawn
NCT00951886	The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally	No drug interventions	Not Available	Not Available	unknown_status
NCT05692622	Home-based Complex Intervention for Children With Ataxia Telangiectasia	No drug interventions	treatment	Not Available	recruiting
NCT04870866	NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia	Nicotinamide	treatment	2	active_not_recruiting
NCT04991701	A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia	No drug interventions	Not Available	Not Available	unknown_status
NCT04605523	Neurofilament Light- Chain in Ataxia Telangiectasia	No drug interventions	Not Available	Not Available	unknown_status
NCT01075438	Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients	Streptococcus pneumoniae type 1 capsular polysaccharide antigen Streptococcus pneumoniae type 10a capsular polysaccharide antigen Streptococcus pneumoniae type 11a capsular polysaccharide antigen Streptococcus pneumoniae type 12f capsular polysaccharide antigen Streptococcus pneumoniae type 14 capsular polysaccharide antigen Streptococcus pneumoniae type 15b capsular polysaccharide antigen Streptococcus pneumoniae type 17f capsular polysaccharide antigen Streptococcus pneumoniae type 18c capsular polysaccharide antigen Streptococcus pneumoniae type 19a capsular polysaccharide antigen Streptococcus pneumoniae type 19f capsular polysaccharide antigen Streptococcus pneumoniae type 2 capsular polysaccharide antigen Streptococcus pneumoniae type 20 capsular polysaccharide antigen Streptococcus pneumoniae type 22f capsular polysaccharide antigen Streptococcus pneumoniae type 23f capsular polysaccharide antigen Streptococcus pneumoniae type 3 capsular polysaccharide antigen Streptococcus pneumoniae type 33f capsular polysaccharide antigen Streptococcus pneumoniae type 4 capsular polysaccharide antigen Streptococcus pneumoniae type 5 capsular polysaccharide antigen Streptococcus pneumoniae type 6b capsular polysaccharide antigen Streptococcus pneumoniae type 7f capsular polysaccharide antigen Streptococcus pneumoniae type 8 capsular polysaccharide antigen Streptococcus pneumoniae type 9n capsular polysaccharide antigen Streptococcus pneumoniae type 9v capsular polysaccharide antigen	Not Available	Not Available	unknown_status
NCT00640003	Baclofen Treatment of Ataxia Telangiectasia	Baclofen Butyric Acid	treatment	0	completed
NCT05531890	Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects	Betamethasone GTX-102	other	1	unknown_status
NCT04513002	Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis	No drug interventions	health_services_research	2	completed
NCT04887311	MBM-01 (Tempol) for the Treatment of Ataxia Telangiectasia	Tempol	treatment	2	unknown_status
NCT03759678	N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)	L-Acetylleucine Trenonacog alfa	treatment	2	recruiting
NCT02345200	Body Composition and Hormonal Status in Ataxia Telangiectasia	No drug interventions	supportive_care	Not Available	completed
NCT05252819	Whole Body MRI for Cancer Surveillance in A-T	No drug interventions	Not Available	Not Available	completed
NCT05692596	The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics	No drug interventions	Not Available	Not Available	recruiting
NCT02345135	Susceptibility to Infections in Ataxia Telangiectasia	No drug interventions	supportive_care	Not Available	completed
NCT02285348	Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T	No drug interventions	diagnostic	Not Available	completed
NCT04037189	Treatment of Leukemia and Lymphoma in Children With Ataxia Telangiectasia	No drug interventions	Not Available	Not Available	unknown_status
NCT05471310	Videoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia	No drug interventions	Not Available	Not Available	completed
NCT03962114	Effects of Vitamin B3 in Patients With Ataxia Telangiectasia	No drug interventions	treatment	2	completed
NCT01942850	International Ataxia Rating Scale in Younger Patients	No drug interventions	Not Available	Not Available	completed
NCT01052623	Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)	Clonidine Estradiol Estradiol valerate Somatotropin	diagnostic	4	unknown_status