Hearth Failure With Reduced Ejection Fraction (HFrEF)

Hearth Failure With Reduced Ejection Fraction (HFrEF) is the indication for 1 drug in DrugBank. It is covered by 1 curated, structured indication.

Also known as
Heart Failure, Systolic · Reduced Ejection Fraction Heart Failure · Systolic Heart Failure · Heart Failure With Reduced Ejection Fraction · Heart Failure With Reduced Ejection Fraction (HF-rEF)
Classified under
Indicated drugs

Resolves to

Vocabularies
MeSHM0502059ICD-10I50.1SNOMED CT155376009MedDRA10024120UMLSC0023212

What you can answer from here — as of November 01, 2026

1Indicated drugWith each drug's targets and mechanism
Listed above
1Structured indicationPopulation, line of therapy, route and combination as fields, not prose
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210Clinical trialsPhase, status and sponsor resolved per trial
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Which approved drugs for Hearth Failure With Reduced Ejection Fraction (HFrEF) share a target, and which companies have late-stage candidates against it?

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