Hearth Failure With Reduced Ejection Fraction (HFrEF) (DBCOND0080197)

Identifiers

Synonyms
Heart Failure Systolic / Reduced ejection fraction heart failure / Heart Failure With Reduced Ejection Fraction (HF-rEF) / Heart Failure, Reduced Ejection Fraction / HFrEF - Heart Failure With Reduced Ejection Fraction / Heart Failure and Reduced Ejection Fraction / Heart Failure With Reduced Ejection Fraction (HFrEF) / Heart Failure With Reduced Ejection Fraction / Heart Failure With Reduced Ejection Fraction, HFrEF / Heart Failure, Systolic / Systolic Heart Failure / Heart Failure With Reduced Ejection Fraction HFrEF / Systolic (congestive) heart failure / Heart failure with reduced ejection fraction (disorder) / Unspecified systolic (congestive) heart failure / Systolic heart failure (disorder) / Left ventricular failure, unspecified / Left ventricular failure / Left ventricular failures / LVF / Left ventricular insufficiency / Failure heart left / Left heart failure / Heart Failure, Left-Sided / Left heart failure (disorder) / Cardiac failure left / Left cardiac failure / Failure left heart

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Ramipril
An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02946853
Junctional AV Ablation in CRT-D: JAVA-CRTNo drug interventionstreatmentNot Availablecompleted
NCT01782677
Bilateral Surgical Resection of Carotid Bodies in Patients With Systolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT02018497
Essential Hypotension and Allostasis RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03534297
Study of Dapansutrile Capsules in Heart Failuretreatment1completed
NCT02156583
Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05884411
Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-ResponseNo drug interventionstreatmentNot Availablerecruiting
NCT01765400
Platelet Inhibition in Patients With Systolic Heart Failuretreatment4completed
NCT03991000
Iron in Patients With Cardiovascular Diseasetreatment3terminated
NCT03755570
How is COGNItive Function Affected by Cardiac Resynchronisation Therapy?No drug interventionsNot AvailableNot Availablesuspended
NCT03871699
Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failuretreatment4unknown_status
NCT01814319
Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failuretreatment2completed
NCT00709241
Psychosocial Patterns and Prognosis in Patients With Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT01735916
MIRACLE EF Clinical StudyNo drug interventionstreatmentNot Availableterminated
NCT03764722
Effectiveness of a Repetitive Use of 24-hour Levosimendan Infusions in Patients With Severe Systolic Heart Failure in Order to Prevent Rehospitalizationstreatment4unknown_status
NCT00348530
Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic CardiomyopathyNo drug interventionstreatment4unknown_status
NCT03036462
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortalitytreatment4completed
NCT02084992
A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT01347567
Heart Failure (HF) Outpatient Monitoring Evaluation (HOME) StudyNo drug interventionsotherNot Availablecompleted
NCT01640769
Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization TherapyNo drug interventionstreatment3unknown_status
NCT02316743
Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical HypothyroidismNo drug interventionstreatment4unknown_status
NCT02223403
Effect of Nitrate-rich Beetroot Juice on Exercise Performance in Heart Failure PatientsNo drug interventionstreatmentNot Availablecompleted
NCT04937790
Effects of Postural Balance Exercises in Patients With Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT01653821
Surgical Removal of Carotid Body in Patients With Systolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT02026102
A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)No drug interventionshealth_services_researchNot Availablecompleted
NCT02958098
My Research Legacy Pilot StudyNo drug interventionsNot AvailableNot Availableterminated
NCT01139697
Hair Cortisol and Testosterone in Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04065893
Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT01646515
Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systolic Heart FailureNo drug interventionstreatment3terminated
NCT05230732
Neuromodulation of Inflammation and Endothelial FunctionNo drug interventionstreatmentNot Availablerecruiting
NCT00833352
Comparison of Right Ventricular Septal and Right Ventricular Apical Pacing in Patients Receiving a CRT-D DeviceNo drug interventionstreatmentNot Availablecompleted
NCT01224899
Surgical Sympathetic Blockade in Heart FailureNo drug interventionstreatment1completed
NCT03446313
Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart)No drug interventionssupportive_careNot Availablecompleted
NCT03157219
Manipal Heart Failure Registry (MHFR)No drug interventionsNot AvailableNot Availableunknown_status
NCT01127334
Pilot Study Using Echocardiography to Evaluate Patients With Heart Failure and Dyssynchrony Who Have a CRT-D DeviceNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01362725
Spinal Cord Stimulation For Heart FailureNo drug interventionstreatment2 / 3completed
NCT02903225
Clinical Value of Heart Rate Variability Indexes to Predict Outcomes After Exercise Training in Chronic Heart FailureNo drug interventionstreatment4completed
NCT00949676
DECIDE-HF: Heart Rate Variability in Heart Failure PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01932294
Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory SupportNo drug interventionsNot AvailableNot Availablecompleted
NCT03984591
A Registry-based Cluster Randomized Trial to Compare the Effect of Spironolactone vs. Eplerenone on Clinical Outcomes in Patients With Symptomatic Systolic Heart FailureNo drug interventionstreatment4enrolling_by_invitation
NCT01566344
Reversal of Cardiomyopathy by Suppression of Frequent Premature Ventricular ComplexesNo drug interventionstreatmentNot Availableunknown_status
NCT02637167
GutHeart: Targeting Gut Microbiota to Treat Heart FailureNo drug interventionstreatment2unknown_status
NCT03041610
Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Reduced Ejection FractionNo drug interventionspreventionNot Availableactive_not_recruiting
NCT04019314
Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)No drug interventionsscreeningNot Availablecompleted
NCT03936608
ECG for Programming in CRTNo drug interventionstreatmentNot Availableterminated
NCT03484780
VisONE Heart Failure Study: PilotNo drug interventionstreatmentNot Availablecompleted
NCT05989503
Initiation of ARNi and SGLT2i in Patients With HFrEFNo drug interventionstreatment4recruiting
NCT03447990
v4 Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491No drug interventionstreatment1 / 2completed
NCT03213821
Safety and Efficacy of High Protein Diet Versus GFR Based Protein Diet in Heart Failure Patients With Renal InsufficiencyNo drug interventionstreatmentNot Availableunknown_status
NCT03057002
UTSW HP [13-C] Pyruvate Injection in HCMNo drug interventionsNot AvailableNot Availablerecruiting
NCT05778084
Effect of Empagliflozin on NT-Pro Brain Natriuretic Peptide in Heart Failure Patients With Reduced Ejection FractionNo drug interventionstreatment4recruiting
NCT06348043
Pumps for Kids, Infants and Neonates (PumpKIN): The Jarvik 2015 Pivotal TrialNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06021587
Interest of Levosimendan Preconditioning for Cardiac Surgery Under CEC in Heart Failure Patients With Impaired Ejection FractionNot AvailableNot Availablerecruiting
NCT06433687
Evaluation of the HekaHeart Platform in Medication Management for Heart Failure PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02113033
VAgal Nerve Stimulation: safeGUARDing Heart Failure PatientsNo drug interventionstreatment2completed
NCT05072054
Comparison of Effects of Atorvastatin Versus Rosuvastatin on Cardiac Function in Heart Failure Patientstreatment4unknown_status
NCT05602454
Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)No drug interventionstreatmentNot Availablerecruiting
NCT06369298
Study of JK07 in Patients With Chronic Heart FailureNo drug interventionstreatment2recruiting
NCT05539898
Improving the Criteria for Selecting Patients for Primary Prevention of Sudden Cardiac Death by Arrhythmic Risk StratificationNo drug interventionsdiagnosticNot Availablerecruiting
NCT03894683
Effect of Melatonin on Cardiovascular and Muscle Mass and Function in Patients With Heart Failuretreatment2unknown_status
NCT03803111
Effects of Iron Therapy and Exercise Training in Patients With Heart Failure and Iron DeficiencyNo drug interventionstreatmentNot Availablewithdrawn
NCT06215911
A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)treatment2recruiting
NCT05077293
Building Electronic Tools To Enhance and Reinforce Cardiovascular Recommendations - Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04539093
Endothelial Function in Mechanical Circulatory SupportNo drug interventionsNot AvailableNot Availablecompleted
NCT05757193
Ketone Pharmacokinetic Study in HFrEFNo drug interventionsother1completed
NCT06229678
Ketones, SGLT2, HFrEFbasic_science0recruiting
NCT06035978
Determination of Drug Levels for Pharmacotherapy of Heart Failuretreatment4not_yet_recruiting
NCT06355388
TRAnscutaneous vaGUS Nerve Stimulation in Patients With Chronic Heart FailureNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05642507
Phase Ib/IIa Trial With AC01 in Patients With HFrEFNo drug interventionstreatment1 / 2recruiting
NCT05774509
Treatment of Non-ischemic Cardiomyopathies by Intravenous Extracellular Vesicles of Cardiovascular Progenitor CellsNo drug interventionstreatment1recruiting
NCT04820556
Gut Microbiota in Chronic Noncommunicable DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT03380156
Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function and Arterial Stiffness in HFrEFNo drug interventionstreatmentNot Availablecompleted
NCT03551756
Assessment of Biomarkers in Patients With Decompensated Heart Failure and Underlying Coronary Artery DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT03198585
Empagliflozin in Heart Failure Patients With Reduced Ejection Fractiontreatment2completed
NCT06552637
Synchronized Diaphragmatic Stimulation in Symptomatic Heart FailureNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03289637
Supplementation With Vitamin D to Patients With Heart Failure (D-Heart).No drug interventionstreatmentNot Availableunknown_status
NCT05971732
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)treatment4recruiting
NCT06249932
Empagliflozin in Heart Failure With Reduced Ejection Fraction and End Stage Renal Diseasetreatment4not_yet_recruiting
NCT06427200
Efficacy and Safety of Lactoferrin in Heart Failure Patientstreatment4not_yet_recruiting
NCT04210375
Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)No drug interventionstreatment1completed
NCT05806970
Email Nudges to Improve GDMT (MRA) Adherence in Heart FailureNo drug interventionshealth_services_researchNot Availablewithdrawn
NCT06299436
Hemodynamic Assessment of underLying myocyTe Function in Right Heart FailureNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06501313
PhotobiomoduLation for pAtientS With Advanced hEart failuReNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03387813
Hemodynamic-GUIDEd Management of Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT02661217
Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Eventsupportive_care4completed
NCT04160624
Transcatheter Aortic Valve Replacement With Extracorporeal Life System SupportNo drug interventionstreatmentNot Availableunknown_status
NCT03479424
Home Outpatient Monitoring and Engagement to Predict HF ExacerbationNo drug interventionsNot AvailableNot Availableterminated
NCT06361524
Gut Microbiome Profiling in Patients With Chronic Heart FailureNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05990296
Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure CareNo drug interventionshealth_services_researchNot Availablerecruiting
NCT03945058
Neuromodulation of Inflammation and Vascular Function in Systolic Heart FailureNo drug interventionstreatmentNot Availableterminated
NCT04514458
Pragmatic Trial of Messaging to Providers About Treatment of Heart FailureNo drug interventionssupportive_careNot Availablecompleted
NCT05855135
Assessment of Combined CCM and ICD Device in HFrEFNo drug interventionstreatmentNot Availablerecruiting
NCT04398563
Heart Failure in Norway: Clinical Characteristics, Mortality and Health Care Resource UseNo drug interventionsNot AvailableNot Availableunknown_status
NCT05344963
Deformation Imaging by Strain in Chronic Heart Failure Over Gliflozins: an Echocardiographic Register on Sodium-GLucose coTransporter-2 InhibitorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04200586
The Effects of SGLTi on Diabetic Cardiomyopathytreatment4unknown_status
NCT05689086
A Virtual Heart Failure Optimization Program for Guideline Directed Medical Therapy and Cardiac RehabilitationNo drug interventionsNot AvailableNot Availablerecruiting
NCT03228030
Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover TrialNo drug interventionstreatment1completed
NCT06241430
The CardioClip StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04249648
Hyperkalaemia and Its Impact on Therapy With RAASiNo drug interventionsNot AvailableNot Availablerecruiting
NCT03574857
Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic Resistancetreatment4terminated
NCT06481657
The Effect of Oxygen Supplementation in Training in Heart Failure Patients on Aerobic Performance and Quality of LifeNo drug interventionsotherNot Availablecompleted
NCT05348226
The ENVI Study: Effect of Entresto on Left Ventricular Remodelling on Cardiac MRINo drug interventionsNot AvailableNot Availablecompleted
NCT06068166
Thoracic Epidural Anesthesia Reduces Mortality and Rehospitalization for Patients With Heart Failure With Reduced Ejection FractionNo drug interventionstreatmentNot Availablecompleted
NCT05974566
Efficacy and Safety of Finerenone in Heart Failure With Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05001165
Dashboard Activated Services and Tele-Health for Heart FailureNo drug interventionshealth_services_researchNot Availablecompleted
NCT04420065
Effects of Preferential Left Ventricular Pacing on Ventriculoarterial Coupling and Clinical Course of Heart FailureNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03870074
CPET Predicts Long-term Survival and Positive Response to CRTNo drug interventionsNot AvailableNot Availablecompleted
NCT02695420
Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection Fractiontreatment2completed
NCT05275920
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)No drug interventionssupportive_careNot Availablecompleted
NCT06195982
Ketones in Heart Failure With Reduced Ejection FractionNo drug interventionstreatment2enrolling_by_invitation
NCT04371731
A Single-centre Research Study to Evaluate the Care4Today® Heart Failure Platform.No drug interventionspreventionNot Availablecompleted
NCT05752760
Pilot Study Lp299v Supplementation in Chronic Heart FailureNo drug interventionsbasic_scienceNot Availablerecruiting
NCT05348460
Effects of a Single Oral Dose of KETone Ester ON Exercise Performance in Patients With Chronic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT06321094
Effect of Vericiguat on Endpoint Events in Acute Coronary Syndrome( ACS)Patients With Ejection Fraction <45%treatment4recruiting
NCT06516562
Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05278962
HF Patients With LVADs Being Treated With SGLT2iNo drug interventionstreatment4recruiting
NCT03209180
Immediate Release Versus Slow Release Carvedilol in Heart Failuretreatment4unknown_status
NCT03701880
Early Use of Ivabradine in Heart FailuretreatmentNot Availableunknown_status
NCT06128980
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced CardiomyopathyNo drug interventionstreatment2 / 3not_yet_recruiting
NCT06273280
Renal-based Optimization of QUADruple Therapy in Patients With Heart Failure With Reduced Ejection Fraction.No drug interventionstreatmentNot Availableactive_not_recruiting
NCT04736329
Telmisartan Versus Enalapril in Heart Failure With Reduced Ejection Fraction Patients With Moderately Impaired Kidney FunctionstreatmentNot Availablecompleted
NCT05952089
A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failuretreatment1completed
NCT05592392
RECOVER-HF Pilot Study of SDS in Heart FailureNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05152940
ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEFNo drug interventionstreatment4recruiting
NCT03951740
Validation of Two Wrist-worn Devices for the Assessment of Energy Expenditure in Cardiac Patients.No drug interventionsotherNot Availablecompleted
NCT04237701
Real-Time Monitoring of Heart Failure Across the Yale New Haven Health SystemNo drug interventionsNot AvailableNot Availablerecruiting
NCT05827172
AF Ablation for HF With Reduced EFNo drug interventionstreatmentNot Availablecompleted
NCT05751772
Improving Knowledge in Heart Failure Inpatient With Therapeutic EducationNo drug interventionshealth_services_researchNot Availableterminated
NCT03644446
Bisoprolol Plasma Residual Concentrations in Chronic Heart FailureNo drug interventionsNot AvailableNot Availableunknown_status
NCT03345446
Circulating RNAs in Acute Congestive Heart FailureNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06543446
Comparative Effectiveness of Prophylactic ICD Versus Non-ICD TherapyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06029712
Heart Failure Polypill at a Safety Net HospitalNo drug interventionstreatment2active_not_recruiting
NCT05580510
" Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "No drug interventionstreatment2 / 3not_yet_recruiting
NCT06344910
PRagmatic Study Of Messaging to Providers of Patients With Heart Failure in Amsterdam UMCNo drug interventionsNot AvailableNot Availablerecruiting
NCT05833581
Consistently Assess Signs and Symptom of Heart FailureNo drug interventionsotherNot Availablerecruiting
NCT06233695
Gender-based Differences in the Outcome of Treatment With Aldosterone Antagonists in Patients With Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT05284955
Screening for Advanced Heart Failure IN Stable outPatientS - The SAINTS Study (SAINTS B)No drug interventionstreatment4recruiting
NCT06286423
Colchicine in Acutely Decompensated HFREFNo drug interventionstreatment4recruiting
NCT03119623
Comparing ARNI With ACE Inhibitor on Endothelial FunctionNo drug interventionstreatment4withdrawn
NCT03082508
A Pivotal Trial to Establish the Efficacy and Safety of Algisyl in Patients With Moderate to Severe Heart FailureNo drug interventionstreatmentNot Availableunknown_status
NCT06359938
Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEFNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03746938
First in Humans to Evaluate Collagen Patches With Stem Cells in Patients With Ischemic Left Ventricular DysfunctionNo drug interventionstreatment1unknown_status
NCT03780803
Effect of Home Rehabilitation on State of Patients With PAH, HFREF and IHDNo drug interventionsotherNot Availablecompleted
NCT06330103
Efficacy of AI EF Screening by Using Smartphone Application Recorded PLAX View Cardiac Ultrasound Video ClipsNo drug interventionsdiagnosticNot Availablecompleted
NCT06398964
Effects of 2-week Ketosis on the Heart's Ketone Body Consumption, Utilization, and Energetic Efficiency in Patients With Chronic Heart FailureNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04638764
Resistance Training in Cardiovascular Disease PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT04600921
Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III StudyNo drug interventionstreatment3terminated
NCT04974021
Iron Intravenous Therapy in Reducing the Burden of Severe Arrhythmias in Heart Failure With Reduced Ejection FractionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04900584
Optimize Heart Failure Care During TRANSitional Period in Patients With Acute Heart Failure.No drug interventionstreatmentNot Availableunknown_status
NCT05299879
Screening for Advanced Heart Failure IN Stable ouTpatientS - The SAINTS StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03877887
Finding Gab in the Treatment of Heart Failure in Assiut University HospitalNo drug interventionsNot AvailableNot Availableunknown_status
NCT05942287
The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.No drug interventionstreatmentNot Availablerecruiting
NCT03480633
Biomechanical Precision Medicine Registry for Patients With and Without Heart FailureNo drug interventionsNot AvailableNot Availablerecruiting
NCT06534151
VITAL - the Heart Failure With Reduced Ejection Fraction Sub-studyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05637853
Telemonitored Fast Track Medical Sequencing for Heart Failure With Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03061747
Multi-centre Observational Registry on Patients With Implantable Devices Remotely MonitoredNo drug interventionsNot AvailableNot Availableunknown_status
NCT05632198
The Effect of Uncertainty in Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT05609097
PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT06576297
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT05409183
Effectiveness of CRD-740 in Heart FailureNo drug interventionstreatment2terminated
NCT06316661
CMR Assessment of Cardiac Microvascular Dysfunction in Patients With HFpEFNo drug interventionsNot AvailableNot Availablerecruiting
NCT04455828
Wearable Remote Monitoring of Heart Rate and Respiratory Rate for Heart FailureNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04921293
Comparison Between Endogenous and Exogenous Ketosis in Patients With Non-ischemic Chronic Heart Failure With Reduced Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT03791593
EVOlocumab in Stable Heart Failure With Reduced Ejection Fraction of Ischemic Etiology: EVO-HF PilotNo drug interventionstreatment2completed
NCT05564793
Improving CRT Outcome With Non-Invasive Cardiac MappingNo drug interventionsdiagnosticNot Availablerecruiting
NCT03072693
Daily Ambulatory Remote Monitoring System For Post-Dischage Management Of ADHFNo drug interventionstreatmentNot Availableunknown_status
NCT06382571
Factors Associated With Sub - Targeted Therapeutic Dose Of Renin - Angiotensin Blockage Among Chronic Heart Failure With Reduced Ejection Fraction PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06455878
Mobile Applet for Weight Management in Obese Heart Failure PatientsNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06526988
Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart FailureNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT03332888
Safety of HMA-CD20 in Patients With HFrEFNo drug interventionstreatment2unknown_status
NCT03334188
Electronic Health Record-leveraged, Patient-centered, Intensification of Chronic Care for HFNo drug interventionsotherNot Availablecompleted
NCT05888688
The Sarcopenia StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04705337
Levosimendan In Ambulatory Heart Failure PatientsNo drug interventionstreatment4not_yet_recruiting
NCT04342832
Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial FibrillationNo drug interventionstreatmentNot Availableunknown_status
NCT03235700
Hyperemic Efficacy of IV Adenosine in HFrEFNo drug interventionsdiagnosticNot Availableunknown_status
NCT04141800
Spanish Study of Hyperkalaemia Incidence and Prognosis in Patients With Heart Failure and Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablecompleted
NCT05795400
Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid CardiomyopathyNo drug interventionstreatmentNot Availablerecruiting
NCT05987670
Triple Cardiovascular Disease Detection With an Artificial Intelligence-enabled StethoscopeNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT06423599
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart FailureNo drug interventionstreatment2 / 3recruiting
NCT03816306
Six Months Clinical and Echocardiographic Outcome of ARNI LCZ696 Therapy in HFrEF PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04281849
Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) ProgramNo drug interventionstreatmentNot Availablecompleted
NCT04112849
Electronic S3 Prediction of Hospital Readmissions for HF ExacerbationNo drug interventionsNot AvailableNot Availablecompleted
NCT06078436
Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEFNo drug interventionstreatmentNot Availablerecruiting
NCT05021419
Efficacy of a Streamlined Heart Failure Optimization ProtocolNo drug interventionstreatmentNot Availableunknown_status
NCT05828719
Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular DysfunctionNo drug interventionstreatmentNot Availablerecruiting
NCT04903717
Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor AntagonistsNo drug interventionstreatmentNot Availablecompleted
NCT05992116
Iron Deficiency in Patients With Heart Failure and Reduced and Mildly Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04112316
Developing Oral LT3 Therapy for Heart Failure - HFrEFNo drug interventionstreatment1 / 2completed
NCT05623358
PHARM Optimal-HF PilotNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT05650658
Left vs Left Randomized Clinical TrialNo drug interventionstreatmentNot Availablerecruiting
NCT04197635
Short-term Effects of Dapagliflozin on Peak VO2 in HFrEFNo drug interventionstreatment4completed
NCT05004363
Lokelma for RAAS Maximisation in CKD & Heart Failure.No drug interventionstreatment3recruiting
NCT06384963
Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEFNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05737186
SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal InsufficiencyNo drug interventionstreatment4terminated
NCT06103539
Pacertool Early Feasibility Study - Safety and PerformanceNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05575557
Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing TreatmentNo drug interventionstreatmentNot Availablerecruiting
NCT06103565
EHR Nudges to Improve Quality of Care in HFNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05583773
SHengXIaN-QuYu DEcoction in the Treatment of Heart Failure With Reduced Ejection FractionNo drug interventionstreatment4recruiting
NCT06479876
Home-Based Cardiac Rehabilitation for Patients With Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT06299176
Whole Heart Radiotherapy for End-stage Heart FailureNo drug interventionstreatment1not_yet_recruiting
NCT04391491
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06442280
SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HFNo drug interventionstreatment4not_yet_recruiting
NCT04498780
Hemodynamic Effects of ARNI on Noninvasive Pressure-volume Analysis in Patients With Chronic Heart FailureNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03136029
Exercise and NO in HFrEFNo drug interventionsbasic_science0recruiting
NCT06488989
Left Bundle Branch Area Pacing in Patients With Heart FailureNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03099889
WHISH-2-Prevent Heart FailureNo drug interventionspreventionNot Availableunknown_status
NCT01922089
Safety and Tolerability of Initiating LCZ696 in Heart Failure PatientsNo drug interventionstreatment2completed
NCT06342492
Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead FailureNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03759392
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart FailureNo drug interventionstreatment3completed
NCT06278844
Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDicationNo drug interventionstreatmentNot Availablerecruiting
NCT04547244
CRTd Responders OptimizationNo drug interventionsNot AvailableNot Availablecompleted
NCT05981144
Exploration of Clonal Hematopoiesis of Indeterminate Potential in Non-ischemic Heart Failure With Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablecompleted
NCT05770167
Effects of Dapagliflozin on Cardiorespiratory Parameters in Heart FailureNo drug interventionsNot AvailableNot Availablerecruiting
NCT03359967
Changes in Intrathoracic Impedance During Sacubitril/Valsartan TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT03141567
LYmphangiogenesis FacTors in Heart Failure StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT05134701
Dapagliflozin Post Marketing Surveillance in HF and CKDNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04590001
Effect of the MobiusHD® in Patients With Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT03524001
Bifocal Right Ventricular PAcing in Right Bundle Branch blocK and Heart Failure With Reduced Ejection Fraction. The Study Tests the Superiority of Right Ventricular Bifocal Stimulation Over VVI Implantable Defibrillator in Right Bundle Branch Block and Heart Failure.No drug interventionstreatmentNot Availableterminated
NCT04803968
The Effect of Combined Upper and Lower Extremity Endurance Training in Patients With ICDNo drug interventionstreatmentNot Availableunknown_status
NCT05365568
Left Bundle Branch Area Pacing for Cardiac Resynchronization Therapy: A Randomized StudyNo drug interventionstreatmentNot Availablerecruiting
NCT03614169
Direct HIS-pacing as an Alternative to BiV-pacing in Symptomatic HFrEF Patients With True LBBBNo drug interventionstreatmentNot Availablecompleted
NCT04676646
Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving SpironolactoneNo drug interventionstreatment4completed
NCT05916612
Influence of Right Ventricular Function on Changes in Exercise Capacity After LVADNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06551012
Neuromuscular Fatigability in Individuals With Heart FailureNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT03317314
Cardiopulmonary Interactions in Patients With Heart FailureNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01035255
This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart FailureNo drug interventionstreatment3terminated
NCT06405555
Midodrine in Heart Failure With Reduced Ejection Fraction With HypotensionNo drug interventionstreatment2 / 3not_yet_recruiting
NCT05824923
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart FailureNo drug interventionstreatment3recruiting
NCT06174623
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic ResistanceNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05799638
Strategy, Efficacy and Safety of Medication Usage in Heart Failure Patients Who Were Intolerable to GDMTNo drug interventionsNot AvailableNot Availablecompleted
NCT05204238
Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE)No drug interventionsNot AvailableNot Availableunknown_status
NCT05250011
Observation of Italian Patients With Heart Failure Being Treated With Dapagliflozin in Clinical PracticeNot AvailableNot Availablecompleted
NCT06528366
Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT05973591
The Impact of Ivabradine on Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy (NIDCM) on Current Medical Therapy EraNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06108076
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and DiabetesNo drug interventionstreatment0recruiting
NCT02970669
Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.No drug interventionsother4completed
NCT02690974
Description of Tolerability of LCZ696 (Sacubitril / Valsartan) in Heart Failure With Reduced Ejection Fraction (HFrEF) Treated in Real Life Settingsupportive_care4completed
NCT06065280
Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT05427370
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)No drug interventionstreatmentNot Availablerecruiting
NCT06478901
Precision of AI-Based Cardiac Ultrasound for LVEF in the ElderlyNo drug interventionsNot AvailableNot Availablecompleted
NCT06240403
Digoxin and Senolysis in Heart Failure and Diabetes MellitusNo drug interventionstreatment2not_yet_recruiting
NCT02099903
Renal Denervation in Patients With Heart Failure Secondary to Chagas DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT03089502
Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related CardiotoxicityNo drug interventionstreatmentNot Availableterminated
NCT04902079
Observational and Prospective Registry on Cardiac Contractility Modulation (CCM) TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04839133
Robotic-assisted Exercise Training in Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT04529577
His-bundle Pacing vs. Right Ventricular Apical Pacing in Patients With Reduced Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT05647577
The Relationship Between Inflammatory ARTritis and CArdiac DIseAseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01553045
Reasons for Variations in Health Related Quality of Life and Symptom Burden in Patients With Atrial FibrillationNo drug interventionsNot AvailableNot Availableunknown_status
NCT02998697
Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemiatreatment2 / 3completed
NCT05933083
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac RehabilitationNo drug interventionstreatmentNot Availablerecruiting
NCT04703361
Effects of Ketones and Niacin in Heart Failure Patientstreatment2completed
NCT05475028
Network Medicine Approaches to Classify Heart Failure With PReserved Ejection Fraction by Signatures of DNA Methylation and Point-of-carE Risk calculaTors (PRESMET)No drug interventionsNot AvailableNot Availablecompleted
NCT02044211
Blended Collaborative Care for Heart Failure and Co-Morbid DepressionNo drug interventionstreatment2 / 3completed
NCT03227393
The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBGNo drug interventionssupportive_careNot Availablewithdrawn
NCT03677271
A Novel Home-based Physical Activity Intervention for Stable Chronic Heart Failure PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT03492788
Optimizing CRT With ECGINo drug interventionstreatmentNot Availableterminated
NCT04522609
Electrostimulation of Skeletal Muscles in Patients Listed for a Heart TransplantNo drug interventionspreventionNot Availableunknown_status
NCT02960685
Telesonography for Visually Estimating Ejection FractionNo drug interventionsNot AvailableNot Availableunknown_status
NCT03387215
Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failuretreatment1 / 2completed
NCT05632432
Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT02810132
Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failuretreatment2completed
NCT03640000
Acute Changes in Bioimpedance During Cardiac Resynchronization TherapyNo drug interventionsdiagnosticNot Availableunknown_status
NCT03917459
COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failuretreatment3completed
NCT04872959
TRANSFORM Heart Failure With Reduced Ejection FractionNo drug interventionstreatmentNot Availablewithdrawn
NCT05702970
Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiencytreatment4not_yet_recruiting
NCT03423342
Nicotinamide Riboside in Systolic Heart FailureNo drug interventionsother1 / 2completed
NCT04703842
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection FractionNo drug interventionstreatment1 / 2recruiting
NCT05988749
Digital Remote Home Monitoring for Heart FailureNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT03079518
Intravenous Iron in paTients With Heart failURe and Reduced Ejection fracTion (HFREF) pLus Iron dEficiencytreatment2completed
NCT04064541
Virtual Visits to Optimize Research Trial Offerings to HF PatientsNo drug interventionshealth_services_researchNot Availablecompleted
NCT01872234
MADIT ASIA Cardiac Resynchronization TrialNo drug interventionstreatment3terminated
NCT04145635
The Aortix CRS Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT01129635
Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance ImagingNo drug interventionstreatmentNot Availablecompleted
NCT04743063
Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and FrailtyNot AvailableNot Availableunknown_status
NCT03387163
Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart FailureNot AvailableNot Availablecompleted
NCT06434025
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiencytreatment3not_yet_recruiting
NCT03511248
Effect of Dietary Nitrate Ingestion in Heart FailureNo drug interventionstreatment2suspended
NCT03830957
Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blockersupportive_careNot Availableunknown_status
NCT05928026
Financial Support in an Underserved and Low-Income Population With Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT01514773
Patient and Physician Survey Determinants of Appropriate ICD UtilizationNo drug interventionsNot AvailableNot Availablecompleted
NCT04112576
Physiological Signals, Activity and Posture for Surface Mounted Insertable Cardiac Monitor in Heart Failure StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02946476
Prognostic Impact of Noncardiac Comorbidities in Heart Failure PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03062176
Interleukin-1 Blockade for the Treatment of Heart Failure in Patients With Advanced Chronic Kidney Diseasetreatment2withdrawn
NCT04763460
Effects of CRT Optimization as Assessed by Cardiac MRNo drug interventionstreatmentNot Availablerecruiting
NCT04611594
Fluid Restriction in Patients With Heart FailureNo drug interventionstreatmentNot Availableunknown_status
NCT02973594
Pulse Reduction On Beta-blocker and Ivabradine Therapybasic_science4completed
NCT02334891
Kyoto Congestive Heart Failure StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06332391
Paced Heart Rate Acceleration for Cardiac ConditioningNo drug interventionstreatmentNot Availablerecruiting
NCT05278429
Robotic-assisted Exercise Training in Heart Failure With Reduced Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT04636892
Evaluating Infrasonic HemodynographyNo drug interventionsdiagnosticNot Availablerecruiting
NCT03305692
ECG Belt vs. Echocardiographic Optimization of CRTNo drug interventionstreatmentNot Availablecompleted
NCT02797340
Metformin Pharmacokinetics in Patients With Chronic and Acute Heart FailureNo drug interventionsother4unknown_status
NCT04325867
Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19No drug interventionshealth_services_researchNot Availableunknown_status
NCT03797001
Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2No drug interventionstreatment2recruiting
NCT04528004
Mechanistic Studies of Nicotinamide Riboside in Human Heart FailureNo drug interventionsbasic_science0recruiting
NCT03398369
Mechanistic Clinical Trial of Advanced Imaging for CRTNo drug interventionstreatmentNot Availablerecruiting
NCT03122769
Cardiac Uptake of Metformin, Visualized by Positron Emission TomographyNo drug interventionstreatment1completed
NCT06336746
Effects of Steep Trendelenburg and Pneumoperitoneum on Cardiac Performance.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01577446
Narrow QRS Ischemic Patients Treated With Cardiac Resynchronization Therapy (NARROW CRT)No drug interventionstreatmentNot Availablecompleted
NCT04420481
Growth Hormone in Ischemic Heart FailureNo drug interventionstreatment3completed
NCT06121323
Physiological Effects of Lactate in Individuals With Chronic Heart FailureNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04179643
NAN-101 in Patients With Class III Heart FailureNo drug interventionstreatment1recruiting
NCT03553303
Pharmacodynamic Effects of Sacubitril/Valsartan on Natriuretic Peptides, Angiotensin and NeprilysinNo drug interventionstreatment4unknown_status
NCT04083690
Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT RecipientsNo drug interventionstreatmentNot Availablerecruiting
NCT03537079
Hypoxic Conditioning in Heart FailureNo drug interventionstreatmentNot Availableunknown_status
NCT03034551
Mobile App With Patient Financial Incentives for Adherence to Heart Failure Medications & Daily Self-WeighingNo drug interventionsotherNot Availablewithdrawn
NCT05989945
HIDRAdenitis Suppurativa and HEART DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02026505
Evaluation of Cardiotoxic Effects of BortezomibNo drug interventionsNot AvailableNot Availablecompleted
NCT03351283
Effect of Sodium Intake on Brain Natriuretic Peptide Levels in Patients With Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT05589428
Low-salt Bread in Heart Failure, Pilot StudyNo drug interventionssupportive_careNot Availablecompleted
NCT03183011
Cardiac Magnetic Resonance Imaging After Cardiac Resynchronization TherapyNo drug interventionsdiagnosticNot Availableunknown_status
NCT03903107
The Fluoroless-CSP Trial Using Electroanatomic MappingNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT03073356
Ketones in Heart Failure - Effects on Cardiac EfficiencyNo drug interventionstreatment2completed
NCT03627585
Reprogramming to Prevent Progressive Pacemaker-induced RemodellingNo drug interventionstreatmentNot Availablecompleted
NCT04201015
Optimising Pacing for Contractility 2No drug interventionstreatment2 / 3recruiting
NCT04992832
Multi-intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Heart Failure With Reduced Ejection Fraction(PRIME-HFrEF Study)No drug interventionstreatment1 / 2completed
NCT05677100
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT02579200
Inspiratory Muscle Training for Breathless Patients With Chronic Obstructive Pulmonary Disease and Heart FailureNo drug interventionstreatment4unknown_status
NCT02080000
R-wave Optimisation in Cardiac Resynchronisation Therapy StudyNo drug interventionstreatmentNot Availablecompleted
NCT03220659
Optimising Pacemaker Therapy Using Multi-point Pacing (the OPT-MPP Study)No drug interventionstreatmentNot Availablecompleted
NCT04803175
Sacubitril/Valsartan Versus Valsartan in Heart Failure With Improved Ejection FractionNo drug interventionsNot AvailableNot Availablerecruiting
NCT02997670
Quartet Lead With Defibrillator Multisite Algorithmic Cardiac Resynchronisation Therapy OptimisationNo drug interventionstreatmentNot Availablewithdrawn
NCT05140642
Safety and Efficacy Study of AI LVEFNo drug interventionsdiagnosticNot Availablecompleted
NCT02438306
CardiAMP™ Cell Therapy for Heart Failure TrialNo drug interventionstreatment3active_not_recruiting
NCT05396313
Prediction of Mortality After CIED Implantation (PM-CIED)No drug interventionsNot AvailableNot Availablerecruiting
NCT04950218
The Psoriasis Echo StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02920918
Treatment of Diabetes in Patients With Systolic Heart FailureNo drug interventionstreatment4completed
NCT05802563
Machine Learning Enabled Time Series Analysis in MedicineNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03425422
ANTHEM-HFrEF Pivotal StudyNo drug interventionstreatmentNot Availableterminated
NCT02401126
Effects of Dietary Nitrate Supplementation on Cardiorespiratory Control in Chronic Heart FailureNo drug interventionstreatment4completed
NCT04570865
Dapagliflozin And Pulmonary Artery Hemodynamics in Heart Failure With Reduced Ejection Fraction Patients With CardioMEMS®No drug interventionstreatment4unknown_status
NCT05726565
Impact of Cardiac Rehabilitation on Acute Heart Failure Patients With Cognitive ImpairmentNo drug interventionsNot AvailableNot Availablecompleted
NCT04264182
STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD SupportNo drug interventionstreatmentNot Availableterminated
NCT06324682
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System PacingNo drug interventionsNot AvailableNot Availablerecruiting
NCT05195931
Cardiac Output in Heart Failure Patients With Mechanical PumpsNo drug interventionsNot AvailableNot Availableterminated
NCT06009276
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness StatusNo drug interventionsNot AvailableNot Availablerecruiting
NCT03374891
A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillatorsNo drug interventionssupportive_careNot Availablecompleted
NCT05008692
Apple-CPET Ted Rogers Understanding Exacerbations of Heart FailureNo drug interventionsNot AvailableNot Availablerecruiting
NCT03392740
Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.No drug interventionsprevention4withdrawn
NCT05387967
Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection FractionNo drug interventionstreatment4completed
NCT02862067
SGLT2 Inhibition in Diabetes and Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT03768804
SyncAV Study: Investigation of the Efficacy of the SyncAV Fusion Pacing Algorithm on ExerciseNo drug interventionstreatmentNot Availableunknown_status
NCT06084468
Cardiac Structure and Function in Patients With Cystic FibrosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03573869
Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE)No drug interventionstreatmentNot Availableunknown_status
NCT03086746
VItamin D as a Novel Determinant of Injurious Cardiac Remodelling After acuTE Myocardial InfarctionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04701112
Acute Hemodynamic Effects of Pacing the His Bundle in Heart FailureNo drug interventionsdiagnosticNot Availablesuspended
NCT03183323
Implementation of Telerehabilitation In Support of HOme-based Physical Exercise for Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT05925608
Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells (CardiALLO)No drug interventionstreatment1enrolling_by_invitation
NCT06450522
Post-Discharge Pharmacist-led Rapid Medication Optimization for Heart Failure (Post-Discharge PHARM-HF)No drug interventionshealth_services_researchNot Availablerecruiting
NCT05277415
Translational and Clinical Aspects of Metabolic, Anabolic and Endothelial Dysfunction in Heart Failuretreatment1 / 2completed
NCT05179070
Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection FractionNo drug interventionstreatment4unknown_status
NCT04331769
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF StudyNo drug interventionstreatmentNot Availablerecruiting
NCT05420012
The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and InflammationNo drug interventionstreatment4active_not_recruiting
NCT03877237
DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection FractionNo drug interventionstreatment3completed
NCT05328752
Safety and Tolerability Study of XXB750 in Heart Failure Participants With Reduced or Mildly Reduced Ejection Fraction (HFrEF/HFmrEF)No drug interventionstreatment1completed
NCT04860596
The Effectiveness of Collaborative Health Management Model on Heart Failure PatientNo drug interventionssupportive_careNot Availableunknown_status
NCT04180696
Mid-Q Response StudyNo drug interventionstreatmentNot Availablecompleted
NCT05136820
Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter StudyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04304560
Value of SGLT2 Inhibitor (Dapagliflozin) as an Added Therapy in Diabetic Patients With Heart Failure With Reduced Ejection Fraction; Randomized Controlled Clinical TrialNo drug interventionstreatment2unknown_status
NCT02874794
Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fractiontreatment4completed
NCT06002386
Vsling™ III: Clinical Evaluation of the Vsling™ Device for Ventricular Repair in Patients With Heart FailureNo drug interventionsdevice_feasibilityNot Availablenot_yet_recruiting
NCT06166823
Electronic Medical Record Alerts to Optimize Medical Therapy in Heart Failure and Reduced Ejection FractionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02468232
Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fractiontreatment3completed
NCT02389933
Multiple Patient Program to Ensure Access to LCZ696 Treatment to Patients Diagnosed With Heart Failure With Reduced Ejection Fraction (HF-rEF)No drug interventionsNot AvailableNot Availableno_longer_available