induction of Intraoperative Hypotension (DBCOND0106166)

Identifiers

Synonyms

Hypotension on induction / Induction of intra-operative hypotension / Procedural hypotension

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Nitroglycerin	A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures.	Atrial natriuretic peptide receptor 1target Aldehyde dehydrogenase, mitochondrialenzyme Epidermal growth factor receptortarget Guanylate cyclase soluble subunit alpha-1target Guanylate cyclase soluble subunit beta-1target
Nitroprusside	A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.	Atrial natriuretic peptide receptor 1target Cytochrome P450 1A1enzyme Guanylate cyclase soluble subunit alpha-1target Guanylate cyclase soluble subunit beta-1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05960604	Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients	No drug interventions	Not Available	Not Available	recruiting
NCT05415436	Analyzing the Relationship Between Speed Propofol is Given and Low Blood Pressure	No drug interventions	other	3	active_not_recruiting
NCT05884918	Intraoperative Hypotension in High-risk Patients Undergoing Surgery	No drug interventions	Not Available	Not Available	recruiting
NCT06316817	FloPatch for Prevention of Hypotension After Induction of General Anesthesia	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT04682717	Perfusion Index as a Predictor of Postinduction Hypotension of General Anesthesia in Geriatric Patients	No drug interventions	Not Available	Not Available	completed
NCT05239234	Ultrasonographic Predictors of Hypotension After Induction	No drug interventions	Not Available	Not Available	completed
NCT04238234	IVC Ultrasonography Versus Plethysmographic Variability Index for Prediction of General Anesthesia Induction Hypotension	No drug interventions	Not Available	Not Available	unknown_status
NCT04991220	Evaluation of the Changes of Pleth Variability Index During Preoxygenation for Predicting Hypotension	No drug interventions	screening	Not Available	unknown_status
NCT04658576	Pre-operative Ultrasonographic Evaluation of Caval Aorta Diameter Index as a Predictor for Post-induction Hypotension	No drug interventions	Not Available	Not Available	completed
NCT04291794	Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion	Propofol	prevention	4	unknown_status
NCT04603469	Hypotension in Children With Down Syndrome With Anesthesia Induction	No drug interventions	Not Available	Not Available	completed
NCT05424510	PoCUS Guided Fluids to Prevent Post-induction Hypotension	No drug interventions	prevention	Not Available	completed
NCT05536323	Bolus Versus Continuous Remimazolam for Anesthetic Induction	Remimazolam	other	Not Available	not_yet_recruiting
NCT03580590	Efficacy of Oral Diltiazem on the Intraoperative Bleeding in Functional Endoscopic Sinus Surgery	Diltiazem Tranexamic acid	prevention	0	unknown_status
NCT06426784	Perfusion Index as a Predictor of Hypotension Following Sub-arachnoid Block Among Patients Undergoing Lower Segment Caesarean Section	No drug interventions	Not Available	Not Available	recruiting
NCT05756933	Arterial Waveform Analysis for Predicting Post-induction Hypotension	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05891951	Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery	No drug interventions	prevention	Not Available	recruiting
NCT03439007	Anesthesia-induced Hypotension and Fluid Responsiveness	No drug interventions	Not Available	Not Available	completed
NCT03787732	Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation	No drug interventions	prevention	4	completed
NCT05497700	Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension	Ephedrine Norepinephrine	treatment	3	unknown_status
NCT05842759	Avoiding Postinduction Hypotension: the Clinical ZERO-HYPOTENSION Proof-of-concept Study	No drug interventions	treatment	Not Available	completed
NCT04573842	Ultrasound Assessment of the Subclavian Vein for Predicting Hypotension in Children After Anaesthesia Induction	No drug interventions	Not Available	Not Available	completed
NCT01669434	Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery	Benazepril Captopril Enalapril Fosinopril Lisinopril Moexipril Perindopril Quinapril Ramipril Trandolapril	treatment	4	completed
NCT05969886	Ventricular-Arterial Coupling: A Predictor of Post-Induction Hypotension	No drug interventions	Not Available	Not Available	recruiting
NCT05355974	Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure	Gluconic Acid Magnesium chloride Norepinephrine Potassium chloride Sodium acetate Sodium chloride	treatment	3	completed
NCT04051073	Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.	No drug interventions	prevention	3	completed
NCT04299776	CirQPOD Shoulder Study	No drug interventions	prevention	Not Available	withdrawn
NCT03237429	The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia	No drug interventions	Not Available	Not Available	unknown_status