Persistent Depressive Disorder (Dysthymia) (DBCOND0128618)

Identifiers

Synonyms
Persistent Depressive Disorder, Dysthymia / Dysthymic Disorder / Dysthymia / Persistent Depressive Disorder / Dysthymia (disorder) / Persistent depressive disorder (disorder) / Depressive personality disorder / Depression, Neurotic / Neurotic depression / Depression neurotic / Depression, unspecified / Depressive illness / Depressive neurosis / Depressive disorder (disorder) / Depressive disorder / Depressive disorders

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Maprotiline
A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
Mirtazapine
A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02458690
eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patientsprevention2completed
NCT00260390
Testosterone Replacement in Middle-Aged Hypogonadal Men With Dysthymia: Parallel Group, Double Blind Randomized Trialtreatment4unknown_status
NCT01852383
Duloxetine Treatment in Elderly With Dysthymiatreatment4completed
NCT00619411
Interpersonal Psychotherapy for Depressed Adolescents and ParentsNo drug interventionstreatment1completed
NCT02739607
Internet-delivered Transdiagnostic Intervention for Anxiety and DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT01385709
The Influence of the Menstrual Cycle on Lithium and Sertraline Blood LevelsNo drug interventionsNot AvailableNot Availablecompleted
NCT04437485
eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risktreatment2completed
NCT01473615
Mindfulness Based Cognitive Therapy for Chronic Pain and Comorbid Unipolar DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT00073359
Effects of Therapist Behavior on the Treatment of Depressed AdolescentsNo drug interventionstreatment1 / 2completed
NCT00096642
Cognitive Behavioral Therapy for Early-Onset DepressionNo drug interventionstreatmentNot Availablecompleted
NCT00688818
Quetiapine in Co-Morbid Depressive and Anxiety DisorderstreatmentNot Availablecompleted
NCT00518986
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depressiontreatment4completed
NCT01542957
Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused InterventionNo drug interventionstreatmentNot Availablecompleted
NCT05118594
Testing a Precision Psychotherapy System for Low-income PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03917550
RECOVERY: A Transdiagnostic Intervention for Anxiety and DepressionNo drug interventionstreatmentNot Availableunknown_status
NCT01942187
A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adultstreatment4withdrawn
NCT00225251
Wellbutrin XL for Dysthymic Disordertreatment4completed
NCT01561105
Improving Depression Care for Elders: Coordinating CenterNo drug interventionstreatmentNot Availablecompleted
NCT01973283
Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adultstreatment4completed
NCT01583400
Enhanced Collaborative Depression Treatment in Primary Care: The RESPECT-D-E TrialNo drug interventionstreatmentNot Availablecompleted
NCT00883519
The Efficacy of Parent Involvement in the Treatment of Adolescent DepressionNo drug interventionstreatment1 / 2completed
NCT00360724
Duloxetine for Chronic Depression: a Double-blind Studytreatment4completed
NCT01892124
Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive SymptomsNo drug interventionspreventionNot Availablecompleted
NCT01528748
Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol DependenceNo drug interventionsNot AvailableNot Availablecompleted
NCT01692574
Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD)No drug interventionstreatmentNot Availablecompleted
NCT03084744
Schema Therapy for Chronic DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT00220701
Escitalopram in the Treatment of Dysthymic Disorder, Double Blindtreatment4completed
NCT01537068
Desvenlafaxine vs. Placebo Treatment of Chronic Depressiontreatment4completed
NCT01948895
Desvenlafaxine Monotherapy in DysthymiatreatmentNot Availablecompleted
NCT03507114
Rumination Focus Cognitive Behavior TherapyNo drug interventionstreatmentNot Availableunknown_status
NCT00592384
Project to Improve Symptoms and Mood in People With Spinal Cord Injurytreatment4completed
NCT04489485
Online System for Identifying and Addressing Teen Depression in Primary CareNo drug interventionsNot AvailableNot Availableunknown_status
NCT01443715
A Stepped Care Model of Adolescent Depression Treatment in Primary CareNo drug interventionstreatment2 / 3completed
NCT00238758
A Study of Omega-3 as a Treatment for Major Depressiontreatment2unknown_status
NCT04235712
Implementation of Harmonized Depression Outcome Measures in a Health SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT00565110
Treating Depression Among Low-Income Patients With CancerNo drug interventionstreatmentNot Availablecompleted
NCT00404755
Dichotic Listening as a Predictor of Medication Response in Depressiontreatment4completed
NCT02112708
Cognitive Behavioral Therapy (REBT/CBT) Evaluation for Dysthymia in the Practice of Clinical Social Work at Primary CareNo drug interventionstreatmentNot Availablecompleted
NCT01447602
A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal BehaviorNo drug interventionstreatment3completed
NCT00296777
Treatment of Depression Following Multiple Brain Teststreatment4completed
NCT03013777
A Trial of Cognitive Behavioral Therapy in Familial DysautonomiaNo drug interventionstreatmentNot Availablecompleted
NCT04235725
Implementation of Harmonized Depression Outcome Measures in a Primary Care Registry and a Mental Health RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT00296725
Dichotic Listening as a Predictor of Medication Response in Depressiontreatment1 / 2completed
NCT03761030
L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adultstreatment4terminated
NCT04664374
Characterizing MyMood Patterns of UseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00482482
Yoga in Unipolar and Bipolar DisordersNo drug interventionstreatmentNot Availablecompleted
NCT02744391
A Study of L-DOPA for Depression and Slowing in Older Adultstreatment4completed
NCT04121091
Pramipexole to Target "Anhedonic Depression"treatment2completed
NCT00579267
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)No drug interventionsNot AvailableNot Availablecompleted
NCT01189812
Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptomstreatment2completed
NCT00234312
Medications for the Treatment of Dysthymic Disorder and Double Depressiontreatment4completed
NCT00296712
Are Two Antidepressants a Good Initial Treatment for Depression?treatment4completed
NCT01882608
Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood DisordersNo drug interventionspreventionNot Availablecompleted
NCT04358900
Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05030272
Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health SettingstreatmentNot Availablerecruiting
NCT06266390
Individualized (fMRI-guided) TMS Treatment for DepressionNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04996433
A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant InpatientsNo drug interventionstreatmentNot Availablerecruiting
NCT05650177
Effects of Mindfulness on Brain Functioning in Depressed PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT06027177
Personalized, Predictive, Precise & Preventive Medicine for Major DepressionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05976945
Imagery Rescripting as Treatment for DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT06311136
Effectiveness of an Ecological Momentary Emotion Regulation InterventionNo drug interventionstreatmentNot Availablerecruiting
NCT04179526
Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing ProblemsNo drug interventionstreatmentNot Availablecompleted
NCT03616665
Feasibility and Effectiveness of a Personalized Inpatient Program for Persistent Depressive DisorderNo drug interventionstreatmentNot Availableunknown_status
NCT01947647
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety DisordersNo drug interventionstreatmentNot Availablecompleted
NCT02752542
Personalized Indications for CBT and Antidepressants in Treating DepressionNo drug interventionstreatment4recruiting
NCT04576741
Blended Mindfulness-Based Intervention for Persistent DepressionNo drug interventionstreatmentNot Availablecompleted
NCT01783080
Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social FunctioningNo drug interventionstreatmentNot Availablecompleted
NCT05221567
Intensive Psychotherapy for Chronic DepressionNo drug interventionstreatmentNot Availablecompleted
NCT05990855
Using Sleep Wearables to Adapt Cognitive-behavioral Therapy for Insomnia in the Context of Depression (CBTiA)No drug interventionstreatmentNot Availablenot_yet_recruiting