Adult Onset Still's Disease (DBCOND0136303)

Identifiers

Synonyms

Adult's Still Disease / Adult-Onset Still´s Disease / Adult-Onset Still Disease / Adult Onset Still Disease / Adult-Onset Still's Disease / Still's disease adult onset / Still's Disease, Adult-Onset / Adult onset Still's disease / Still Disease, Adult-Onset / AOSD / Adult onset Still's disease (disorder) / Juvenile rheumatoid arthritis with systemic onset / Still's disease / Systemic onset juvenile chronic arthritis (disorder) / Juvenile-Onset Still Disease

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Canakinumab	An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA).	Interleukin-1 betatarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01002781	Efficacy and Safety of Tocilizumab in Adult's Still Disease	Tocilizumab	treatment	2	unknown_status
NCT02204293	Canakinumab for Treatment of Adult-onset Still's Disease	Canakinumab	treatment	2	terminated
NCT03276650	Admission of Adult-onset Still Disease Patients in the ICU	No drug interventions	Not Available	Not Available	completed
NCT03311854	A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)	Emapalumab	treatment	2	completed
NCT04750863	Evaluation of Adult Onset Still Disease Classification Criteria and Differential Diagnosis at Eighteen Months of Follow-up	No drug interventions	Not Available	Not Available	completed
NCT03651193	Multi-center Registration Study of Adult Onset Still's Disease in Chinese Population	No drug interventions	Not Available	Not Available	unknown_status
NCT04402086	Rheumatology Patient Registry and Biorepository	No drug interventions	Not Available	Not Available	recruiting
NCT05432960	Efficacy and Safety Clinical Study of RPH-104 in Adult Onset Still's Disease (AOSD)	Goflikicept	treatment	3	withdrawn
NCT01033656	Treatment of Refractory Adult-onset Still's Disease With Anakinra: a Randomized Study	Anakinra Azathioprine Leflunomide Methotrexate	treatment	2	completed
NCT04717635	Study of Efficacy and Safety of Canakinumab in Japanese Patients With AOSD	Canakinumab	treatment	3	active_not_recruiting
NCT04752371	A Study to Evaluate Camoteskimab in Participants With Still's Disease	Camoteskimab	treatment	1	terminated
NCT06497491	An Efficacy and Safety Study of GNR-086 (canakinumab Biosimilar) and Ilaris® in Patients with Adult-onset Still's Disease	Canakinumab	treatment	3	recruiting
NCT03510442	Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions	No drug interventions	Not Available	Not Available	recruiting
NCT06405152	Assessment of Macrophage Activation syndromE in STill's Disease	No drug interventions	Not Available	Not Available	recruiting
NCT03265132	A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Still's Disease (SJIA and AOSD)	Anakinra	treatment	3	terminated
NCT05814159	A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)	Anakinra	treatment	3	active_not_recruiting
NCT05715736	Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of APB-R3	No drug interventions	treatment	1	completed
NCT02143986	Glycosylated Ferritin in Macrophagic Activation Syndromes	No drug interventions	Not Available	Not Available	unknown_status
NCT05927454	Acostill ( RaDiCo Cohort) (RaDiCo Acostill)	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT00094900	Interleukin-1 Trap to Treat Autoinflammatory Diseases	Rilonacept	treatment	2	completed
NCT02398435	Therapeutic Use of Tadekinig Alfa in Adult-onset Still's Disease	Tadekinig alfa	treatment	2	completed