Remikiren

Star0

DB00212ExperimentalSmall molecule

Remikiren is an orally active, high specificity renin inhibitor.

Mechanism: Several in vivo experiments have shown that remikiren is specific for renin and does not decrease arterial pressure by an unrelated mechanism.
Curator reviewed
Primary indication: For the treatment of hypertension and heart failureCurator reviewed
Formula / weight: C₃₃H₅₀N₄O₆S · 630.838 g/mol (avg)
Code names: RO-42-5892

Resolves to

Compound

UNIILC7FBL96A4CAS126222-34-2ChEMBLCHEMBL31601ChEBI8803PubChem6324659KEGGC07465

Clinical / RWD

ATCC09XA01PharmGKBPA164774779

Structure

InChIKeyUXIGZRQVLGFTOU-VQXQMPIVSA-NSMILESCC(C)(C)S(=O)(=O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1

Targets

P00797REN

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

637Drug interactionsStructured to mechanism, not free text

1ATC codeIncluding every combination product, plus 6 drug categories

13+ReferencesStructured and connected to the statements they support

Which drugs share a target with Remikiren, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account