Lymecycline is a tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections. It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy.
- Mechanism
- Curator reviewed · 3 references
Normally, the ribosome synthesizes proteins through the binding of aminoacyl-tRNA to the mRNA-ribosome complex. Lymecycline binds to the 30S ribosomal subunit, preventing amino-acyl tRNA from binding to the A site of the ribosome, which prevents the elongation of polypeptide chains. This results in bacteriostatic actions, treating various infections.
- Primary indication
- Lymecycline is used for the treatment of acne in addition to other susceptible infections; propionibacterium is often the cause of acne.Curator reviewed · 2 structured indications
- Formula / weight
- C29H38N4O10 · 602.6328 g/mol (avg)
- Also known as
- N-Lysinomethyltetracycline
Resolves to
AHEVKYYGXVEWNO-UEPZRUIBSA-NSMILES[H][C@@]12C[C@@]3([H])C(C(=O)C4=C(O)C=CC=C4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(=O)NCNCCCC[C@H](N)C(O)=O)=C(O)[C@H]2N(C)CWhat you can answer from here — as of September 11, 2026
Which drugs share a target with Lymecycline, and which of those have an active Phase 3 trial?
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