Acetohydroxamic acid is a synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea.
- Mechanism
- Curator reviewed
Acetohydroxamic Acid reversibly inhibits the bacterial enzyme urease. This inhibits the hydrolysis of urea and production of ammonia in urine infected with urea-splitting organisms, leading to a decrease in pH and ammonia levels. As antimicrobial agents are more effective in such conditions, the effectiveness of these agents is amplified, resulting in a higher cure rate.
- Primary indication
- Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.Curator reviewed · 1 structured indication
- Formula / weight
- C2H5NO2 · 75.0666 g/mol (avg)
- First approval
- United States, 1983
- Also known as
- Acetic acid, oxime · Acetohydroxamate · Acetohydroximic acid · Acetylhydroxamic acid · Cetohyroxamic acid
- Brand names
Resolves to
RRUDCFGSUDOHDG-UHFFFAOYSA-NSMILESCC(=O)NOWhat you can answer from here — as of September 11, 2026
Which drugs share a target with Acetohydroxamic acid, and which of those have an active Phase 3 trial?
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