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DB00919ApprovedVet approvedWithdrawnSmall molecule
Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. An antibiotic produced by Streptomyces spectabilis.
- Mechanism
- Curator reviewed
Spectinomycin is an inhibitor of protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit. It is bactericidal in its action.
- Primary indication
- For use in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae.Curator reviewed
- Formula / weight
- C14H24N2O7 · 332.3496 g/mol (avg)
- First approval
- Canada, 1972 · United States, 1971
- Code names
- Antibiotic 2233wp · CHX-3101
Resolves to
Clinical / RWD
Structure
InChIKey
UNFWWIHTNXNPBV-WXKVUWSESA-NSMILES[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]1([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]1([H])O2Targets
What you can answer from here — as of September 12, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Spectinomycin, and which of those have an active Phase 3 trial?