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DB01604ApprovedWithdrawnSmall molecule
Pivampicillin is an ampicillin prodrug used to treat a variety of infections. Pivalate ester analog of ampicillin.
- Mechanism
- Curator reviewed
Ampicillin (the active metabolite of pivampicillin) has a bactericidal action resulting from inhibition of cell wall mucopeptide biosynthesis.
- Primary indication
- or the treatment of respiratory tract infections (including acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia); ear, nose and throat infections; gynecological infections; urinary tract infections (including acute uncomplicated gonococcal urethritis) when caused by...Curator reviewed · 1 structured indication
- Formula / weight
- C22H29N3O6S · 463.547 g/mol (avg)
- First approval
- Canada, 1984
- Also known as
- Ampicillin pivaloyloxymethyl ester · Pivaloylampicillin · Pivaloyloxymethyl ampicillinate
- Code names
- MK-191
Resolves to
Clinical / RWD
Structure
InChIKey
ZEMIJUDPLILVNQ-ZXFNITATSA-NSMILES[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(=O)OCOC(=O)C(C)(C)CTargets
What you can answer from here — as of September 13, 2026
2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Pivampicillin, and which of those have an active Phase 3 trial?