7-Hydroxystaurosporine

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DB01933InvestigationalSmall molecule

7-Hydroxystaurosporine: Overview.

Mechanism: Pharmacologically active on Cyclin-dependent kinase 2, Cyclin-dependent kinase 6, and Cyclin-dependent kinase 4
Curator reviewed
Formula / weight: C₂₈H₂₆N₄O₄ · 482.5304 g/mol (avg)
Code names: KRX-0601 · NSC-638850 · UCN-01

Resolves to

Compound

UNII7BU5H4V94ACAS112953-11-4ChEMBLCHEMBL1236539PubChem72271

Structure

InChIKeyPBCZSGKMGDDXIJ-HQCWYSJUSA-NSMILES[H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4[C@@H](O)NC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13

Targets

P24941CDK2Q00534CDK6P11802CDK4O14757CHEK1O15530PDPK1

What you can answer from here — as of September 13, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

39Drug interactionsStructured to mechanism, not free text

18Clinical trialsPhase, status and sponsor resolved per trial

25+ReferencesStructured and connected to the statements they support

Which drugs share a target with 7-Hydroxystaurosporine, and which of those have an active Phase 3 trial?

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